ESBL-Producing <i>Escherichia</i> <i>coli</i> Carrying CTX-M Genes Circulating among Livestock, Dogs, and Wild Mammals in Small-Scale Farms of Central Chile

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dc.contributor.authorBenavides, Julio A.
dc.contributor.authorSalgado-Caxito, Marilia
dc.contributor.authorOpazo-Capurro, Andres
dc.contributor.authorGonzalez Munoz, Paulina
dc.contributor.authorPineiro, Ana
dc.contributor.authorOtto Medina, Macarena
dc.contributor.authorRivas, Lina
dc.contributor.authorMunita, Jose
dc.contributor.authorMillan, Javier
dc.date.accessioned2025-01-20T22:20:56Z
dc.date.available2025-01-20T22:20:56Z
dc.date.issued2021
dc.description.abstractAntibiotic-resistant bacteria of critical importance for global health such as extended-spectrum beta-lactamases-producing (ESBL)-Escherichia coli have been detected in livestock, dogs, and wildlife worldwide. However, the dynamics of ESBL-E. coli between these animals remains poorly understood, particularly in small-scale farms of low and middle-income countries where contact between species can be frequent. We compared the prevalence of fecal carriage of ESBL-E. coli among 332 livestock (207 cows, 15 pigs, 60 horses, 40 sheep, 6 goats, 4 chickens), 82 dogs, and wildlife including 131 European rabbits, 30 rodents, and 12 Andean foxes sharing territory in peri-urban localities of central Chile. The prevalence was lower in livestock (3.0%) and wildlife (0.5%) compared to dogs (24%). Among 47 ESBL-E. coli isolates recovered, CTX-M-group 1 was the main ESBL genotype identified, followed by CTX-M-groups 2, 9, 8, and 25. ERIC-PCR showed no cluster of E. coli clones by either host species nor locality. To our knowledge, this is the first report of ESBL-E. coli among sheep, cattle, dogs, and rodents of Chile, confirming their fecal carriage among domestic and wild animals in small-scale farms. The high prevalence of ESBL-E. coli in dogs encourages further investigation on their role as potential reservoirs of this bacteria in agricultural settings.
dc.fuente.origenWOS
dc.identifier.doi10.3390/antibiotics10050510
dc.identifier.issn2079-6382
dc.identifier.urihttps://doi.org/10.3390/antibiotics10050510
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/94637
dc.identifier.wosidWOS:000653356200001
dc.issue.numero5
dc.language.isoen
dc.revistaAntibiotics-basel
dc.rightsacceso restringido
dc.subjectantimicrobial resistance
dc.subjectbla
dc.subject(CTX-M)
dc.subjectChile
dc.subjectdomestic animals
dc.subjectE
dc.subjectcoli
dc.subjectextended-spectrum beta-lactamases
dc.subjectwildlife
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleESBL-Producing <i>Escherichia</i> <i>coli</i> Carrying CTX-M Genes Circulating among Livestock, Dogs, and Wild Mammals in Small-Scale Farms of Central Chile
dc.typeartículo
dc.volumen10
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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