Predictors of acute coronary syndrome without ST segment elevation and risk stratification in the chest pain unit

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dc.contributor.authorGabrielli, Luigi A.
dc.contributor.authorCastro, Pablo F.
dc.contributor.authorVerdejo, Hugo E.
dc.contributor.authorMcNab, Paul A.
dc.contributor.authorLlevaneras, Silvana A.
dc.contributor.authorMardonez, Jose M.
dc.contributor.authorCorbalan, Ramon L.
dc.date.accessioned2024-01-10T14:22:37Z
dc.date.available2024-01-10T14:22:37Z
dc.date.issued2008
dc.description.abstractBackground: Nearly 10016 of patients with an actual acute coronary syndrome (ACS) are discharged with an inadequate diagnosis. Aim: To select clinical and laboratory predictors to identify patients with a high likelihood of ACS in the Chest Pain Unit. Material and methods: Prospective evaluation of patients consulting in a Chest Pain Unit of a University Hospital. Initial assessment was standardized and included evaluation of pain characteristics, electrocardiogram and Troponin I. Independent predictors of ACS were identified with a multiple logistic regression. Results: In a four years period, 1,168 patients aged 62 +/- 23 years (69% males), were studied. After initial evaluation, 62% of the patients were admitted to the hospital for further testing and in 71% of them, a definite diagnosis of ACS was made. No events were reported by patients directly discharged from the Chest Pain Unit. Independent predictors associated With a higher likelihood of ACS were an abnormal electrocardiogram at the initial evaluation (Odds ratio (OR) 5.37, 95% confidence intervals (CI) 3.61-7.99), two or more cardiovascular risk factors (OR 2.16, 95% CI 1.21-2.84), cervical irradiation of the pain (OR 1.84, 95% CI 1.25-2.69), age over 65 years (OR 1. 73, 95% CI (1.32-2.27) and a Troponin I above the upper normal limit (OR: 5.68, 95% CI 3.72-8.29). Conclusions: Simple clinical findings allow an appropriate identification of patients with a high likelihood of ACS without specialized methods for myocardial ischemia detection (Rev Med Chile 2008; 136: 442-50).
dc.format.extent9 páginas
dc.fuente.origenWOS
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:18769786
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79969
dc.identifier.wosidWOS:000256712400004
dc.information.autorucFacultad de Medicina; Verdejo Pinochet, Hugo Eduardo; S/I; 1001175
dc.issue.numero4
dc.language.isoes
dc.nota.accesoSin adjunto
dc.pagina.final450
dc.pagina.inicio442
dc.publisherSOC MEDICA SANTIAGO
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsregistro bibliográfico
dc.subjectacute coronary syndrome
dc.subjectrisk factors
dc.subjecttroponin T-1
dc.subjectMYOCARDIAL-INFARCTION
dc.subjectCLINICAL PREDICTORS
dc.subjectUNSTABLE ANGINA
dc.subjectEMERGENCY-ROOM
dc.subjectEXERCISE
dc.subjectCENTERS
dc.subjectHISTORY
dc.subjectTRIAL
dc.subjectSCORE
dc.subjectTIMI
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titlePredictors of acute coronary syndrome without ST segment elevation and risk stratification in the chest pain unit
dc.typeartículo
dc.volumen136
sipa.codpersvinculados1001175
sipa.indexWOS
sipa.indexPubmed
sipa.trazabilidadCarga SIPA;09-01-2024
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