Perfil clínico y epidemiológico de los casos de tuberculosis atendidos en una red de salud universitaria en Santiago de Chile entre los años 2000-2010

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dc.catalogadorjwg/yvc
dc.contributor.authorMorgado Ahumada, Álvaro Esteban
dc.contributor.authorKöhnenkampf, Ruth
dc.contributor.authorBalcells Marty, María Elvira
dc.contributor.authorNavarrete, Pablo
dc.contributor.authorGarcía Cañete, Patricia Del Carmen
dc.date.accessioned2023-11-10T19:27:00Z
dc.date.available2023-11-10T19:27:00Z
dc.date.issued2012
dc.description.abstractBackground: The incidence and epidemiological profile of tuberculosis (TB) has changed significantly in the recent years in Chile. Aim: To evaluate the clinical and epidemiological characteristics of TB cases diagnosed in the last decade at a university hospital in Santiago. Material and Methods: The Mycobacterium tuberculosis culture registry of the microbiology laboratory was reviewed. Medical records of patients with a positive culture registered between 2000 and 2010 were retrieved and analyzed. Results: Two hundred forty positive Mycobacterium tuberculosis cultures were identified and the medical records of 158 of these patients were accessed for analysis. The median age was 53 years (range: 3 to 89), 55.1% were female and nearly 42% had extra-pulmonary TB. Among known risk factors, 32.9% of patients were older than 65 years, 4.4% were health care workers and 3.9% immigrants. Twenty eight percent (41/145) had some type of immunosuppression at diagnosis: 11.7% HIV infection and 16.6% were using immunosuppressive drugs. In this group, a previous tuberculin skin test was done in only 5 cases (12.2%). Adverse events related to TB treatment were reported in 21.3% of cases (17/80). No cases of fulminant hepatitis or death from this cause were identified. Four of 92 patients that had a complete follow up during treatment, died. Two of these patients were receiving steroids. Conclusions: Almost one third of TB cases occurred among immunosuppressed patients and 42% were extra-pulmonary forms. The prevention of TB reactivation in this group should be strengthened.
dc.fechaingreso.objetodigital2023-11-10
dc.fuente.origenScopus
dc.identifier.doi10.4067/S0034-98872012000700004
dc.identifier.issn0034-9887
dc.identifier.pubmedidPUBMED_ID: 23282696
dc.identifier.scopusidSCOPUS_ID: 84868334571
dc.identifier.urihttp://www.scielo.cl/pdf/rmc/v140n7/art04.pdf
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75295
dc.information.autorucEscuela de Medicina; Balcells Marty Maria Elvira; 0000-0002-7223-9665; 7462
dc.information.autorucEscuela de Medicina; Morgado Ahumada, Álvaro Esteban; S/I; 156282
dc.information.autorucEscuela de Medicina; García Cañete, Patricia Del Carmen; 0000-0002-5983-2392; 73909
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final858
dc.pagina.inicio853
dc.revistaRevista Médica de Chile
dc.rightsacceso abierto
dc.subjectImmunosuppression
dc.subjectMyocbacterium tuberculosis
dc.subjectRisk factors
dc.subjectTuberculosis
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titlePerfil clínico y epidemiológico de los casos de tuberculosis atendidos en una red de salud universitaria en Santiago de Chile entre los años 2000-2010
dc.title.alternativeClinical and epidemiological profile of tuberculosis in a university hospital in Santiago, Chile
dc.typeartículo
dc.volumen140
sipa.codpersvinculados7462
sipa.codpersvinculados156282
sipa.codpersvinculados73909
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