Use of autologous platelet derivatives for secondary alveoloplasty in patients with cleft lip and palate: a protocol for a systematic review and meta-analysis

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dc.catalogadoryvc
dc.contributor.authorCampolo González, Andrés Francisco
dc.contributor.authorHeider Contreras, Claudia Andrea
dc.contributor.authorCañete Campos, Ismael Ignacio
dc.contributor.authorVerdugo Paiva, María Francisca
dc.contributor.authorBravo Jeria, Rocío
dc.contributor.authorMorovic, Carmen Gloria
dc.contributor.authorRada Giacamán, Gabriel Alejandro
dc.date.accessioned2024-01-02T19:11:45Z
dc.date.available2024-01-02T19:11:45Z
dc.date.issued2021
dc.descriptionMedRxiv: the preprint server for health sciences
dc.description.abstractObjective: To assess the effectiveness and safety of autologous platelet derivatives, specifically platelet-rich plasma (PRP) or platelet-rich fibrin (PRF), for secondary alveoloplasty in patients with cleft lip and palate. Eligibility criteria: We will include randomized trials evaluating the effect of autologous platelet derivatives on newly bone formed after secondary alveoloplasty in cleft lip and palate patients. Two reviewers will independently screen each study for eligibility, data extraction, and bias assessment using the Cochrane "risk of bias" tool. We will pool the results using meta-analysis and apply the GRADE system to assess the certainty of the evidence for each outcome. Data sources: A comprehensive search will include all relevant randomized controlled trials (RCTs), the ongoing investigation reported in specialty congresses and trials regardless of language or ublication status (published, unpublished, in press, and progress). We will conduct searches in the following databases: Cochrane Central Register of Controlled Trials (CENTRAL), PUBMED, Embase, and LILACS. We will screen trial registries and other sources in order to identify articles that might have been missed in the electronic searches. Ethics and dissemination: As researchers will not access information that could identify an individual participant, obtaining ethical approval was waived.
dc.fechaingreso.objetodigital2024-01-02
dc.fuente.origenORCID
dc.identifier.doi10.1101/2021.06.28.21259643
dc.identifier.urihttps://doi.org/10.1101/2021.06.28.21259643
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75600
dc.identifier.urihttps://www.medrxiv.org/content/10.1101/2021.06.28.21259643v1#page
dc.information.autorucEscuela de Medicina; Campolo González, Andrés Francisco; 0000-0003-3110-5991; 1015697
dc.information.autorucEscuela de Medicina; Heider Contreras, Claudia Andrea; 0000-0003-1111-4380; 238023
dc.information.autorucEscuela de Medicina; Cañete Campos, Ismael Ignacio; 0000-0003-1776-7067; 250759
dc.information.autorucCentro de Evidencias UC; Verdugo Paiva, María Francisca; 0000-0003-0199-9744; 1084579
dc.information.autorucEscuela de Medicina; Rada Giacamán, Gabriel Alejandro; 0000-0003-2435-0710; 11470
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final13
dc.pagina.inicio1
dc.rightsacceso abierto
dc.rights.licenseAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectPlatelet-rich fibrin
dc.subjectPlatelet-rich plasma
dc.subjectSecondary alveoloplasty
dc.subjectCleft lip
dc.subjectCleft palate
dc.subjectAlveolar Bone Grafting
dc.subjectSystematic review
dc.subjectProtocol
dc.subjectMeta-analysis
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleUse of autologous platelet derivatives for secondary alveoloplasty in patients with cleft lip and palate: a protocol for a systematic review and meta-analysis
dc.typepreprint
sipa.codpersvinculados1015697
sipa.codpersvinculados238023
sipa.codpersvinculados250759
sipa.codpersvinculados1084579
sipa.codpersvinculados11470
sipa.trazabilidadORCID;2024-01-01
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