Breast cancer and pregnancy: A comparative analysis of a Chilean cohort
dc.contributor.author | Sánchez, C. | |
dc.contributor.author | Acevedo Claros, Francisco Nicolás | |
dc.contributor.author | Medina, L. | |
dc.contributor.author | Ibáñez, C. | |
dc.contributor.author | Razmilic Valdés, Dravna Nichi | |
dc.contributor.author | Navarro Ortega, María Elena | |
dc.contributor.author | Camus, M. | |
dc.date.accessioned | 2020-01-14T01:29:01Z | |
dc.date.available | 2020-01-14T01:29:01Z | |
dc.date.issued | 2014 | |
dc.description.abstract | Introduction: Recent reports show that pregnancy-associated breast cancer (PABC) survival is similar to that of non-pregnant young patients. We evaluate the characteristics and prognosis of PABC patients treated in our cancer centre. Patients and methods: We identified patients with invasive PABC who were treated between 1999 and May 2013 and compared their characteristics with a no PABC cohort of similar age. Results: The prevalence of PABC was 1% (n = 17). The median age was 35 years (range: 29– 42 years). The initial tumour was suspected clinically in 93% of the cases. Total mastectomy rates were higher in women with PABC (78.6% versus 40.5%, p = 0.02), and more tumours in the PABC group were triple negative, epidermal growth factor type 2 (HER2)–positive, and at advanced stages; however, these differences were not statistically significant. While estimated overall survival at ten years was higher in the non-PABC group (75.5% versus 80.5%, p = 0.043), disease-specific survival (DSS) rate at ten years was not statistically different between groups (83.9% for PABC and 75.5% for unrelated pregnancy BC, p = 0.37). Conclusions: PABC is a rare event. In our cohort, it tended to be more aggressive. Compared with a similar age cohort, the DSS was not worse. | |
dc.identifier.doi | 10.3332/ecancer.2014.434 | |
dc.identifier.issn | 1754-6605 | |
dc.identifier.uri | https://doi.org/10.3332/ecancer.2014.434 | |
dc.identifier.uri | https://repositorio.uc.cl/handle/11534/27465 | |
dc.issue.numero | No. 1 | |
dc.language.iso | en | |
dc.revista | ecancermedicalscience | es_ES |
dc.rights | acceso abierto | |
dc.subject | Breast cancer | es_ES |
dc.subject | Pregnancy | es_ES |
dc.subject | Prognosis | es_ES |
dc.subject | Antineoplastic agent | es_ES |
dc.subject | Epidermal growth factor receptor 2 | es_ES |
dc.subject | Adult | es_ES |
dc.subject | Article | es_ES |
dc.subject | Breast carcinoma | es_ES |
dc.subject | Cancer center | es_ES |
dc.subject | Cancer chemotherapy | es_ES |
dc.subject | Cancer patient | es_ES |
dc.subject | Cancer prognosis | es_ES |
dc.subject | Cancer surgery | es_ES |
dc.subject | Chile | es_ES |
dc.subject | Clinical Article | es_ES |
dc.subject | Cohort analysis | es_ES |
dc.subject | Controlled study | es_ES |
dc.subject | Diagnostic test accuracy study | es_ES |
dc.subject | Disease severity | es_ES |
dc.subject | Disease specific Survival | es_ES |
dc.subject | Female | es_ES |
dc.subject | Histopathology | es_ES |
dc.subject | Human | es_ES |
dc.subject | Immunohistochemistry | es_ES |
dc.subject | Mastectomy | es_ES |
dc.subject | Overall survival | es_ES |
dc.subject | Partial mastectomy | es_ES |
dc.subject | Predictive value | es_ES |
dc.subject | Pregnancy associated breast cancer | es_ES |
dc.subject | Pregnancy disorder | es_ES |
dc.subject | Pregnant woman | es_ES |
dc.subject | Prevalence | es_ES |
dc.subject.ddc | 610 | |
dc.subject.dewey | Medicina y salud | es_ES |
dc.title | Breast cancer and pregnancy: A comparative analysis of a Chilean cohort | es_ES |
dc.type | artículo | |
dc.volumen | Vol. 8 | |
sipa.codpersvinculados | 135644 | |
sipa.codpersvinculados | 119540 | |
sipa.codpersvinculados | 146063 | |
sipa.codpersvinculados | 114040 | |
sipa.codpersvinculados | 100233 | |
sipa.codpersvinculados | 100235 |
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