Breast cancer and pregnancy: A comparative analysis of a Chilean cohort

dc.contributor.authorSánchez, C.
dc.contributor.authorAcevedo Claros, Francisco Nicolás
dc.contributor.authorMedina, L.
dc.contributor.authorIbáñez, C.
dc.contributor.authorRazmilic Valdés, Dravna Nichi
dc.contributor.authorNavarro Ortega, María Elena
dc.contributor.authorCamus, M.
dc.date.accessioned2020-01-14T01:29:01Z
dc.date.available2020-01-14T01:29:01Z
dc.date.issued2014
dc.description.abstractIntroduction: Recent reports show that pregnancy-associated breast cancer (PABC) survival is similar to that of non-pregnant young patients. We evaluate the characteristics and prognosis of PABC patients treated in our cancer centre. Patients and methods: We identified patients with invasive PABC who were treated between 1999 and May 2013 and compared their characteristics with a no PABC cohort of similar age. Results: The prevalence of PABC was 1% (n = 17). The median age was 35 years (range: 29– 42 years). The initial tumour was suspected clinically in 93% of the cases. Total mastectomy rates were higher in women with PABC (78.6% versus 40.5%, p = 0.02), and more tumours in the PABC group were triple negative, epidermal growth factor type 2 (HER2)–positive, and at advanced stages; however, these differences were not statistically significant. While estimated overall survival at ten years was higher in the non-PABC group (75.5% versus 80.5%, p = 0.043), disease-specific survival (DSS) rate at ten years was not statistically different between groups (83.9% for PABC and 75.5% for unrelated pregnancy BC, p = 0.37). Conclusions: PABC is a rare event. In our cohort, it tended to be more aggressive. Compared with a similar age cohort, the DSS was not worse.
dc.identifier.doi10.3332/ecancer.2014.434
dc.identifier.issn1754-6605
dc.identifier.urihttps://doi.org/10.3332/ecancer.2014.434
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/27465
dc.issue.numeroNo. 1
dc.language.isoen
dc.revistaecancermedicalsciencees_ES
dc.rightsacceso abierto
dc.subjectBreast canceres_ES
dc.subjectPregnancyes_ES
dc.subjectPrognosises_ES
dc.subjectAntineoplastic agentes_ES
dc.subjectEpidermal growth factor receptor 2es_ES
dc.subjectAdultes_ES
dc.subjectArticlees_ES
dc.subjectBreast carcinomaes_ES
dc.subjectCancer centeres_ES
dc.subjectCancer chemotherapyes_ES
dc.subjectCancer patientes_ES
dc.subjectCancer prognosises_ES
dc.subjectCancer surgeryes_ES
dc.subjectChilees_ES
dc.subjectClinical Articlees_ES
dc.subjectCohort analysises_ES
dc.subjectControlled studyes_ES
dc.subjectDiagnostic test accuracy studyes_ES
dc.subjectDisease severityes_ES
dc.subjectDisease specific Survivales_ES
dc.subjectFemalees_ES
dc.subjectHistopathologyes_ES
dc.subjectHumanes_ES
dc.subjectImmunohistochemistryes_ES
dc.subjectMastectomyes_ES
dc.subjectOverall survivales_ES
dc.subjectPartial mastectomyes_ES
dc.subjectPredictive valuees_ES
dc.subjectPregnancy associated breast canceres_ES
dc.subjectPregnancy disorderes_ES
dc.subjectPregnant womanes_ES
dc.subjectPrevalencees_ES
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleBreast cancer and pregnancy: A comparative analysis of a Chilean cohortes_ES
dc.typeartículo
dc.volumenVol. 8
sipa.codpersvinculados135644
sipa.codpersvinculados119540
sipa.codpersvinculados146063
sipa.codpersvinculados114040
sipa.codpersvinculados100233
sipa.codpersvinculados100235
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