A methodological survey of the analysis, reporting and interpretation of Absolute Risk ReductiOn in systematic revieWs (ARROW): a study protocol

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dc.contributor.authorAlonso-Coello, Pablo
dc.contributor.authorCarrasco-Labra, Alonso
dc.contributor.authorBrignardello-Petersen, Romina
dc.contributor.authorNeumann Burotto, Gonzalo Ignacio
dc.contributor.authorAkl, Elie A
dc.contributor.authorSun, Xin
dc.contributor.authorJohnston, Bradley C
dc.contributor.authorBriel, Matthias
dc.contributor.authorBusse, Jason W
dc.contributor.authorGlujovsky, Demián
dc.contributor.authorGranados, Carlos E
dc.contributor.authorIorio, Alfonso
dc.contributor.authorIrfan, Affan
dc.contributor.authorGarcía, Laura M
dc.contributor.authorMustafa, Reem A
dc.contributor.authorRamirez-Morera, Anggie
dc.contributor.authorSolà, Iván
dc.contributor.authorTikkinen, Kari A O
dc.contributor.authorEbrahim, Shanil
dc.contributor.authorVandvik, Per O
dc.contributor.authorZhang, Yuqing
dc.contributor.authorSelva, Anna
dc.contributor.authorSanabria, Andrea J
dc.contributor.authorZazueta, Oscar E
dc.contributor.authorVernooij, Robin W M
dc.contributor.authorSchünemann, Holger J
dc.contributor.authorGuyatt, Gordon H
dc.date.accessioned2019-10-16T20:14:47Z
dc.date.available2019-10-16T20:14:47Z
dc.date.issued2013
dc.date.updated2019-10-14T19:08:23Z
dc.description.abstractAbstract Background Clinicians, providers and guideline panels use absolute effects to weigh the advantages and downsides of treatment alternatives. Relative measures have the potential to mislead readers. However, little is known about the reporting of absolute measures in systematic reviews. The objectives of our study are to determine the proportion of systematic reviews that report absolute measures of effect for the most important outcomes, and ascertain how they are analyzed, reported and interpreted. Methods/design We will conduct a methodological survey of systematic reviews published in 2010. We will conduct a 1:1 stratified random sampling of Cochrane vs. non-Cochrane systematic reviews. We will calculate the proportion of systematic reviews reporting at least one absolute estimate of effect for the most patient-important outcome for the comparison of interest. We will conduct multivariable logistic regression analyses with the reporting of an absolute estimate of effect as the dependent variable and pre-specified study characteristics as the independent variables. For systematic reviews reporting an absolute estimate of effect, we will document the methods used for the analysis, reporting and interpretation of the absolute estimate. Discussion Our methodological survey will inform current practices regarding reporting of absolute estimates in systematic reviews. Our findings may influence recommendations on reporting, conduct and interpretation of absolute estimates. Our results are likely to be of interest to systematic review authors, funding agencies, clinicians, guideline developers and journal editors.
dc.fuente.origenBiomed Central
dc.identifier.citationSystematic Reviews. 2013 Dec 13;2(1):113
dc.identifier.doi10.1186/2046-4053-2-113
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/26560
dc.identifier.urihttps://doi.org/10.1186/2046-4053-2-113
dc.issue.numeroNo. 113
dc.language.isoen
dc.pagina.final8
dc.pagina.inicio1
dc.revistaSystematic Reviewses_ES
dc.rightsacceso abierto
dc.rights.holderAlonso-Coello et al.; licensee BioMed Central Ltd.
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.otherMedicina - Métodos estadísticoses_ES
dc.subject.otherMedicinaes_ES
dc.titleA methodological survey of the analysis, reporting and interpretation of Absolute Risk ReductiOn in systematic revieWs (ARROW): a study protocoles_ES
dc.typeartículo
dc.volumenVol. 2
sipa.codpersvinculados13498
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