Oral rapid test: an alternative to traditional HIV screening in Chile

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dc.catalogadorvzp
dc.contributor.authorIrarrázabal Vargas, Lisette Paola
dc.contributor.authorFerrer Lagunas, Lilian Marcela
dc.contributor.authorCianelli, Rosina
dc.contributor.authorLara, Loreto
dc.contributor.authorReed Reiley, Diane
dc.contributor.authorLevy, Judith
dc.contributor.authorPerez Cortes, Carlos Miguel
dc.date.accessioned2024-07-17T14:54:40Z
dc.date.available2024-07-17T14:54:40Z
dc.date.issued2013
dc.description.abstractObjective. To compare the sensitivity and specificity of an Oral Rapid Test (ORT) to that of the Enzyme-Linked Immunosorbent Assay (ELISA) for HIV testing in Santiago, Chile; to track the number of study participants returning for ELISA testing results; and to analyze the participants' perceptions of the ORT compared to the ELISA.
dc.description.abstractMethods. A total of 497 people were recruited in Santiago, Chile: 153 had previously tested positive for HIV, and 344 were of unknown status. Participants were tested for HIV using both the ELISA and the ORT to examine and compare specificity and sensitivity. Qualitative data were collected from 22 participants to compare perceptions of the testing experience with ORT versus ELISA.
dc.description.abstractResults. The ELISA reported 184 (37%) of the 497 participants as being "positive" for HIV antibodies; the ORT showed 181 (36.4%) as being "reactive" for HIV. The ORT showed a sensitivity of 98.4% (95.7%-99.9%, 95% Confidence Interval) and specificity of 100%. The Kappa test produced K = 0.983 (P < 0.0001). Of the 344 participants whose HIV status was unknown at the start of the study, 55 failed to return for their ELISA results. Participants positively perceived ORT as having reduced both waiting time and anxiety over obtaining their test results. ORT oral swabbing appeared more practical and less invasive than drawing blood for the ELISA.
dc.description.abstractConclusions. The ORT and ELISA were statistically equal in specificity and sensitivity. ORT provides quicker results, potentially ensuring that more people receive them, and does not require handling of or exposure to potentially hazardous blood products.
dc.description.funderFOGARTY INTERNATIONAL CENTER
dc.description.funderNATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES
dc.description.funderNATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
dc.description.funderNational Institute on Minority Health and Health Disparities
dc.description.funderFIC NIH HHS
dc.description.funderNIAID NIH HHS
dc.description.funderNIMHD NIH HHS
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.issn1020-4989
dc.identifier.pubmedidMEDLINE:23939368
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/87083
dc.identifier.wosidWOS:000323099100007
dc.information.autorucEscuela de Enfermería; Ferrer Lagunas, Lilian Marcela; S/I; 70272
dc.information.autorucActividades Universitarias-Dri; Reed Reiley, Diane; S/I; 180931
dc.information.autorucEscuela de Medicina; Perez Cortes, Carlos Miguel; S/I; 66650
dc.information.autorucEscuela de Enfermería; Irarrazabal Vargas, Lisette Paola; S/I; 2904
dc.issue.numero6
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final432
dc.pagina.inicio427
dc.publisherPAN AMER HEALTH ORGANIZATION
dc.revistaREVISTA PANAMERICANA DE SALUD PUBLICA-PAN AMERICAN JOURNAL OF PUBLIC HEALTH
dc.rightsacceso restringido
dc.subjectHIV infections, diagnosis
dc.subjectAIDS serodiagnosis
dc.subjectHIV seroprevalence
dc.subjectClinical laboratory techniques
dc.subjectDisease prevention
dc.subjectChile
dc.subjectHIV-1/2 Test
dc.subjectWhole-blood
dc.subjectPerformance
dc.subjectPreferences
dc.subjectExperience
dc.subjectAccuracy
dc.subjectProgram
dc.subject.ddc610
dc.subject.deweyMedicina y salud
dc.titleOral rapid test: an alternative to traditional HIV screening in Chile
dc.typeartículo
dc.volumen33
sipa.codpersvinculados70272
sipa.codpersvinculados180931
sipa.codpersvinculados66650
sipa.codpersvinculados2904
sipa.trazabilidadWOS;05-06-2021
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