An Ultrasound Model to Discriminate the Risk of Thyroid Carcinoma

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dc.contributor.authorMiguel Dominguez, Jose
dc.contributor.authorBaudrand, Rene
dc.contributor.authorCerda, Jaime
dc.contributor.authorCampusano, Claudia
dc.contributor.authorFardella, Carlos
dc.contributor.authorArteaga, Eugenio
dc.contributor.authorCruz, Francisco
dc.contributor.authorSolar, Antonieta
dc.contributor.authorArias, Tatiana
dc.contributor.authorMosso, Lorena
dc.date.accessioned2024-01-10T12:37:36Z
dc.date.available2024-01-10T12:37:36Z
dc.date.issued2011
dc.description.abstractRationale and Objectives: Thyroid nodules are common on ultrasonographic examination and are mostly benign. Ultrasound characteristics may help discriminate thyroid carcinoma (TC) from benign nodules. The aims of this study. were to identify ultrasonographic characteristics associated with IC and to validate a previously proposed model based on the presence of three ultrasonographic characteristics.,
dc.description.abstractMaterials and Methods: From a protocolized prospective registry of 1108 fine needle aspiration biopsies performed during a 16-month period at an ambulatory center, the ultrasonographic characteristics of IC and non-TC biopsies were compared. Adjusted odds ratios (ORs) and likelihood ratios for TC were estimated for eight combinations of three previously identified characteristics (microcalcifications, hypoechogenicity, and irregular borders).
dc.description.abstractResults: Microcalcifications (OR, 6.6; 95% confidence interval [CI], 4.4-9.9), hypoechogenicity (OR, 4.7; 95% CI, 2.8-8.0), and irregular borders (OR, 4.3; 95% CI, 2.8-6.5) were independently associated with TC. When added to a logistic regression model, the three ultrasonographic characteristics remained statistically significant. In the absence of these three features, the likelihood ratio for TC was 0.1 (95% CI, 0.0-0.2), while in their simultaneous presence, the likelihood ratio was 11(95% CI, 6.6-19.0).
dc.description.abstractConclusions: The absence or simultaneous presence of three simple ultrasonographic characteristics generates a large change of pretest probability of TC and could avoid unnecessary fine needle aspiration biopsy.
dc.fechaingreso.objetodigital2024-03-18
dc.format.extent4 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.acra.2010.09.018
dc.identifier.eissn1878-4046
dc.identifier.issn1076-6332
dc.identifier.pubmedidMEDLINE:21075018
dc.identifier.urihttps://doi.org/10.1016/j.acra.2010.09.018
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/76884
dc.identifier.wosidWOS:000286699200016
dc.information.autorucMedicina;Arias T ;S/I;136
dc.information.autorucMedicina;Arteaga E ;S/I;98586
dc.information.autorucMedicina;Baudrand R;S/I;1024
dc.information.autorucMedicina;Campusano C ;S/I;75485
dc.information.autorucMedicina;Cerda J ;S/I;3935
dc.information.autorucMedicina;Dominguez JM;S/I;9629
dc.information.autorucMedicina;Fardella C ;S/I;66235
dc.information.autorucMedicina;Mosso L ;S/I;88201
dc.information.autorucMedicina;Solar A ;S/I;6498
dc.issue.numero2
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final245
dc.pagina.inicio242
dc.publisherELSEVIER SCIENCE INC
dc.revistaACADEMIC RADIOLOGY
dc.rightsacceso restringido
dc.subjectThyroid nodule
dc.subjectthyroid cancer
dc.subjectbiopsy
dc.subjectfine needle
dc.subjectultrasonography
dc.subjectFINE-NEEDLE-ASPIRATION
dc.subjectNODULE SHAPE
dc.subjectBIOPSY
dc.subjectMALIGNANCY
dc.subjectMANAGEMENT
dc.subjectSYSTEM
dc.subjectUS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleAn Ultrasound Model to Discriminate the Risk of Thyroid Carcinoma
dc.typeartículo
dc.volumen18
sipa.codpersvinculados136
sipa.codpersvinculados98586
sipa.codpersvinculados1024
sipa.codpersvinculados75485
sipa.codpersvinculados3935
sipa.codpersvinculados9629
sipa.codpersvinculados66235
sipa.codpersvinculados88201
sipa.codpersvinculados6498
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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