Hyperhidrosis in sleep disorders - A narrative review of mechanisms and clinical significance

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dc.contributor.authorIdiaquez, Juan
dc.contributor.authorCarlos Casar, Juan
dc.contributor.authorArnardottir, Erna S.
dc.contributor.authorAugust, Elias
dc.contributor.authorSantin, Julia
dc.contributor.authorIturriaga, Rodrigo
dc.date.accessioned2024-01-10T14:25:45Z
dc.date.available2024-01-10T14:25:45Z
dc.date.issued2022
dc.description.abstractHyperhidrosis is characterized by excessive sweating beyond thermoregulatory needs that affects patients' quality of life. It results from an excessive stimulation of eccrine sweat glands in the skin by the sympathetic nervous system. Hyperhidrosis may be primary or secondary to an underlying cause. Nocturnal hyperhidrosis is associated with different sleep disorders, such as obstructive sleep apnea, insomnia, restless legs syndrome/periodic limb movement during sleep and narcolepsy. The major cause of the hyperhidrosis is sympathetic overactivity and, in the case of narcolepsy type 1, orexin deficiency may also contribute. In this narrative review, we will provide an outline of the possible mechanisms underlying sudomotor dysfunction and the resulting nocturnal hyperhidrosis in these different sleep disorders and explore its clinical relevance.
dc.description.funderGrant Fondecyt
dc.fechaingreso.objetodigital2024-05-09
dc.fuente.origenWOS
dc.identifier.doi10.1111/jsr.13660
dc.identifier.eissn1365-2869
dc.identifier.issn0962-1105
dc.identifier.urihttps://doi.org/10.1111/jsr.13660
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/80370
dc.identifier.wosidWOS:000811369100001
dc.information.autorucFacultad de Ciencias Biológicas; Iturriaga Aguera, Rodrigo Manuel; S/I; 59784
dc.language.isoen
dc.nota.accesoSin adjunto
dc.publisherWILEY
dc.rightsregistro bibliográfico
dc.subjecthyperhidrosis
dc.subjectinsomnia
dc.subjectnarcolepsy
dc.subjectperiodic limb movement
dc.subjectrestless legs syndrome
dc.subjectsleep apnea
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleHyperhidrosis in sleep disorders - A narrative review of mechanisms and clinical significance
dc.typereseña
sipa.codpersvinculados59784
sipa.indexWOS
sipa.trazabilidadCarga SIPA;09-01-2024
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