Leukocytoclastic Vasculitis as Early Manifestation of Epstein-Barr Virus-Positive Diffuse Large B-Cell Lymphoma of the Elderly

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dc.contributor.authorZoroquiain, Pablo
dc.contributor.authorGonzalez, Sergio
dc.contributor.authorMolgo, Montserrat
dc.contributor.authorRodriguez, Alejandra
dc.contributor.authorValbuena, Jose R.
dc.date.accessioned2024-01-10T13:49:55Z
dc.date.available2024-01-10T13:49:55Z
dc.date.issued2012
dc.description.abstractExtensive necrotizing vasculitis (ENV) is a rare paraneoplastic phenomenon, and the majority of cases reported are associated with hematolymphoid neoplasms. Histologically, most cases of ENV represent leukocytoclastic vasculitis (LCV). Here we report the clinicopahological features of a 68-year-old man with ENV associated to a Epstein Barr virus-positive diffuse large B-cell lymphoma (EBV+DLBCL) of the elderly, a newly recognized lymphoproliferative disorder, most likely representing a paraneoplastic manifestation. The patient was treated with standard chemotherapy regimen for malignant lymphoma. Due to the extensive involvement of the extremities by ENV, surgical debridement was not feasible and a novel therapy based on CHITOSAN apposits was initiated with overall good response and subsequent re-epithelization of the skin lesions. The patient died of sepsis secondary to a Pseudomona pneumonia 17 months after diagnosis.
dc.fechaingreso.objetodigital2024-05-22
dc.format.extent5 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1097/DAD.0b013e3182318dd9
dc.identifier.eissn1533-0311
dc.identifier.issn0193-1091
dc.identifier.pubmedidMEDLINE:22197862
dc.identifier.urihttps://doi.org/10.1097/DAD.0b013e3182318dd9
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79491
dc.identifier.wosidWOS:000303054500021
dc.information.autorucMedicina;Gonzalez S ;S/I;99856
dc.information.autorucMedicina;Molgo M;S/I;100088
dc.information.autorucMedicina;Rodriguez A;S/I;11188
dc.information.autorucMedicina;Valbuena J;S/I;1004589
dc.information.autorucMedicina;Zoroquiain P ;S/I;175130
dc.issue.numero3
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final334
dc.pagina.inicio330
dc.publisherLIPPINCOTT WILLIAMS & WILKINS
dc.revistaAMERICAN JOURNAL OF DERMATOPATHOLOGY
dc.rightsacceso restringido
dc.subjectparaneoplastic vasculitis
dc.subjectleukocytoclastic vasculitis
dc.subjectEBV plus DLBCL
dc.subjectCUTANEOUS VASCULITIS
dc.subjectLYMPHOPROLIFERATIVE DISORDERS
dc.subjectDERMAL BURN
dc.subjectCLASSIFICATION
dc.subjectCHEMOTHERAPY
dc.subjectMICROARRAY
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleLeukocytoclastic Vasculitis as Early Manifestation of Epstein-Barr Virus-Positive Diffuse Large B-Cell Lymphoma of the Elderly
dc.typeartículo
dc.volumen34
sipa.codpersvinculados99856
sipa.codpersvinculados100088
sipa.codpersvinculados11188
sipa.codpersvinculados1004589
sipa.codpersvinculados175130
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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