Prophylaxis against fungal infections in solid organ and hematopoietic stem cells transplantation

Simple item page
dc.contributor.authorRabagliati, Ricardo
dc.contributor.authorElena Santolaya, M.
dc.date.accessioned2024-01-10T13:52:37Z
dc.date.available2024-01-10T13:52:37Z
dc.date.issued2012
dc.description.abstractInvasive fungal infections are an important cause of morbidity and mortality in SOT and HSCT recipients. The main species involved are Candida spp. and Aspergillus spp, less frequently Cryptococcus spp., causal agents of mucormycosis and Fusarium spp. Usually occur within the first six months post-transplant, but they do it later, especially during episodes of rejection, which maintains the state of immune system involvement. Prophylaxis recommendations are specific to each type of transplant. In liver transplantation use of fluconazole is recommended only in selected cases by high risk factor for invasive fungal infections (A1). If the patient has a high risk of aspergillosis, there are some suggestions for adults population to use amphotericin B-deoxycholate, liposomal amphotericin B or caspofungin (C2) without being validated none of these recommendations in pediatric population. In adult lung transplant patients where the risk of aspergillosis is higher than in other locations, we recommend universal prophylaxis with itraconazole 200 mg/day, nebulised liposomal amphotericin B or voriconazole (C2), no validated recommendations for pediatrics. In HSCT, universal prophylaxis is recommended only in allogeneic and autologous selected cases. The most accepted indication is fluconazole (A1), and posaconazole (A1) or micafungin (A1) in selected cases with high risk of aspergillosis.
dc.fechaingreso.objetodigital2024-05-30
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.doi10.4067/S0716-10182012000500002
dc.identifier.eissn0717-6341
dc.identifier.issn0716-1018
dc.identifier.urihttps://doi.org/10.4067/S0716-10182012000500002
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79675
dc.identifier.wosidWOS:000310561600002
dc.information.autorucMedicina;Rabagliati R;S/I;59169
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final18
dc.pagina.inicio11
dc.publisherSOC CHILENA INFECTOLOGIA
dc.revistaREVISTA CHILENA DE INFECTOLOGIA
dc.rightsacceso abierto
dc.subjectFungus
dc.subjectCandida
dc.subjectAspergillus
dc.subjectyeasts
dc.subjectmoulds
dc.subjectprophylaxis
dc.subjectamphotericin
dc.subjectfluconazole
dc.subjectvoriconazole
dc.subjectposaconazole
dc.subjectcaspofungin
dc.subjectmicafungin
dc.subjecttransplants
dc.subjectsolid organ transplantation
dc.subjecthematopoietic stem cells transplantation
dc.subjectINVASIVE PULMONARY ASPERGILLOSIS
dc.subjectLIPOSOMAL AMPHOTERICIN-B
dc.subjectANTIFUNGAL PROPHYLAXIS
dc.subjectRISK-FACTORS
dc.subjectPROLONGED NEUTROPENIA
dc.subjectORAL ITRACONAZOLE
dc.subjectCONTROLLED-TRIAL
dc.subjectSINGLE-CENTER
dc.subjectDOUBLE-BLIND
dc.subjectRECIPIENTS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleProphylaxis against fungal infections in solid organ and hematopoietic stem cells transplantation
dc.typeartículo
dc.volumen29
sipa.codpersvinculados59169
sipa.indexWOS
sipa.indexScielo
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Prophylaxis against fungal infections in solid organ and hematopoietic stem cells transplantation.pdf
Size:
3.44 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas