Prognostic assessment in COPD: Health related quality of life and the BODE index

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dc.contributor.authorMarin, Jose M.
dc.contributor.authorCote, Claudia G.
dc.contributor.authorDiaz, Orlando
dc.contributor.authorLisboa, Carmen
dc.contributor.authorCasanova, Ciro
dc.contributor.authorLopez, Maria V.
dc.contributor.authorCarrizo, Santiago J.
dc.contributor.authorPinto Plata, Victor
dc.contributor.authorDordelly, Luis J.
dc.contributor.authorNekach, Hafida
dc.contributor.authorCelli, Bartolome R.
dc.date.accessioned2024-01-10T13:16:43Z
dc.date.available2024-01-10T13:16:43Z
dc.date.issued2011
dc.description.abstractRationale: COPD is a debilitating disease with increasing mortality worldwide. The BODE index evaluates disease severity and the St George's Respiratory Questionnaire (SGRQ) measures health status.
dc.description.abstractObjective: To identify the relationship between BODE index and the SGRQ and to test the predictive value of both tools against survival.
dc.description.abstractMethods: Open cohort study of 1398 COPD patients (85% male) followed for up to 10 years. Measurements and main results: At the time of the inclusion, clinical data, forced spirometry and 6 min walking distance were determined and BODE index and SGRQ were calculated. Vital status and cause of death were documented at the end of follow-up.
dc.description.abstractResults: The cohort's mean of FEV1% predicted was 46 +/- 18%, BODE index was 3.6 +/- 2.5, and SGRQ% total score was 49 +/- 20. The SGRQ scores increased progressively as severity of COPD increased by BODE quartiles. The correlation between SGRQ and BODE index was good (r = 0.58, p < 0.0001). Both tests correlated with COPD survival (BODE = -0.4 vs. SGRQ = -0.20, p < 0.0001). The area under the curve (AUC) for the BODE index was 0.77 vs. 0.66 for the SGRQ% total score (p < 0.001).
dc.description.abstractConclusions: Health status as measured by SGRQ worsens with disease severity evaluated by the BODE index. Both tools predict mortality and provide complimentary information in the evaluation of patients with COPD. (C) 2011 Elsevier Ltd. All rights reserved.
dc.fechaingreso.objetodigital17-04-2024
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.rmed.2011.01.007
dc.identifier.eissn1532-3064
dc.identifier.issn0954-6111
dc.identifier.pubmedidMEDLINE:21282050
dc.identifier.urihttps://doi.org/10.1016/j.rmed.2011.01.007
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/78607
dc.identifier.wosidWOS:000291136800014
dc.information.autorucMedicina;Diaz O ;S/I;78564
dc.information.autorucMedicina;Lisboa C;S/I;98551
dc.issue.numero6
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final921
dc.pagina.inicio916
dc.publisherW B SAUNDERS CO LTD
dc.revistaRESPIRATORY MEDICINE
dc.rightsacceso restringido
dc.subjectCOPD
dc.subjectBODE index
dc.subjectQuality of life
dc.subjectMortality
dc.subjectOBSTRUCTIVE PULMONARY-DISEASE
dc.subjectEXERCISE CAPACITY
dc.subjectMORTALITY
dc.subjectDYSPNEA
dc.subjectREHABILITATION
dc.subjectPREDICTOR
dc.subjectDIAGNOSIS
dc.subjectDISTANCE
dc.subjectTIME
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titlePrognostic assessment in COPD: Health related quality of life and the BODE index
dc.typeartículo
dc.volumen105
sipa.codpersvinculados78564
sipa.codpersvinculados98551
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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