Daptomycin: pharmacological characteristics and its role in the treatment of gram positive infections

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dc.contributor.authorAraos, Rafael
dc.contributor.authorGarcia, Patricia
dc.contributor.authorChanqueo, Leonardo
dc.contributor.authorLabarca, Jaime
dc.date.accessioned2024-01-10T12:38:14Z
dc.date.available2024-01-10T12:38:14Z
dc.date.issued2012
dc.description.abstractDaptomycin recently made available in Chile, belongs to a new family of antimicrobials known as lypopeptides. Daptomycin has a unique mechanism of action and a potent bactericidal activity over susceptible agents. It is active against a number of clinically significant Gram positive cocci, including strains of Staphylococcus aureus and Enterococcus spp., both susceptible and resistant to classic antimicrobials. Daptomycin has been approved for clinical use in skin and soft tissue infections, and for S. aureus bacteremia in adult patients. Ongoing trials suggest that daptomycin is also useful in the treatment of other infections such as osteomyelitis, biofilm producing infections, and in immunocompromised patients, particularly onco-hematologic patients. The main adverse reaction associated with daptomycin use is myopathy, usually mild and reversible.
dc.format.extent5 páginas
dc.fuente.origenWOS
dc.identifier.eissn0717-6341
dc.identifier.issn0716-1018
dc.identifier.pubmedidMEDLINE:22689024
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77008
dc.identifier.wosidWOS:000303085500001
dc.information.autorucMedicina;Chanqueo L ;S/I;146071
dc.information.autorucMedicina;Garcia P ;S/I;73909
dc.information.autorucMedicina;Labarca J ;S/I;62874
dc.issue.numero2
dc.language.isoes
dc.nota.accesoSin adjunto
dc.pagina.final131
dc.pagina.inicio127
dc.publisherSOC CHILENA INFECTOLOGIA
dc.revistaREVISTA CHILENA DE INFECTOLOGIA
dc.rightsregistro bibliográfico
dc.subjectDaptomycin
dc.subjectGram-positive infections
dc.subjectpharmacology
dc.subjectresistance
dc.subjectSTAPHYLOCOCCUS-AUREUS
dc.subjectIN-VITRO
dc.subjectENTEROCOCCUS-FAECALIS
dc.subjectEXPERIENCE
dc.subjectENDOCARDITIS
dc.subjectCOMBINATION
dc.subjectMANAGEMENT
dc.subjectBACTEREMIA
dc.subjectRESISTANCE
dc.subjectVANCOMYCIN
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleDaptomycin: pharmacological characteristics and its role in the treatment of gram positive infections
dc.typeartículo
dc.volumen29
sipa.codpersvinculados146071
sipa.codpersvinculados73909
sipa.codpersvinculados62874
sipa.indexWOS
sipa.indexScielo
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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