Common mental disorders and psychological distress in systemic lupus erythematosus are not associated with disease activity

Simple item page
dc.contributor.authorJarpa, E.
dc.contributor.authorBabul, M.
dc.contributor.authorCalderon, J.
dc.contributor.authorGonzalez, M.
dc.contributor.authorMartinez, M. E.
dc.contributor.authorBravo Zehnder, M.
dc.contributor.authorHenriquez, C.
dc.contributor.authorJacobelli, S.
dc.contributor.authorGonzalez, A.
dc.contributor.authorMassardo, L.
dc.date.accessioned2024-01-10T13:46:59Z
dc.date.available2024-01-10T13:46:59Z
dc.date.issued2011
dc.description.abstractPsychiatric diagnosis in patients with systemic lupus erythematosus (SLE) is controversial: variations have been reported in frequency, diagnostic assays, associations with disease activity, autoantibodies, and contributing social factors. Eighty-three consecutive non-selected Chilean patients with SLE were evaluated for: (i) 26 common mental disorders according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), using the Mini-International Neuropsychiatric Interview (MINI-plus); (ii) psychological suffering measured by Hospital Anxiety and Depression Scale (HADS); (iii) ACR 1999 neuropsychiatric (NP) SLE criteria; (iv) SLE disease activity (SLEDAI-2K); (v) cumulative damage (SLICC/ACR); and (vi) anti-ribosomal P antibodies by enzyme-linked immunoassay and immunoblot. Psychiatric diagnoses occurred in 44.6% of patients; the most frequent (21.7%) was major depressive episode (MDE). No association with lupus activity was observed in patients with a DSM-IV diagnosis or MDE or psychological suffering. ACR 1999 NPSLE criteria were present in 42.2% of patients, the majority corresponding to mood (28.9%) or anxiety disorders (15.6%). Suicidal risk was present in 9.6% of patients. Anti-ribosomal P antibodies (13.3%) were not associated with DSM-IV diagnosis. Severe psychiatric disorders in SLE are common and not associated with disease activity. Lupus (2011) 20, 58-66.
dc.description.funderFondo Nacional de Ciencia y Tecnologia; Fondo Nacional de A Areas Prioritarias; Programa de Financiamiento Basal para Centros Cientificos y Tecnologicos de Excelencia
dc.description.funderMillennium Institute for Fundamental and Applied Biology 'Ministerio de Planificacion'
dc.fechaingreso.objetodigital2024-05-20
dc.format.extent9 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1177/0961203310381773
dc.identifier.eissn1477-0962
dc.identifier.issn0961-2033
dc.identifier.pubmedidMEDLINE:21078764
dc.identifier.urihttps://doi.org/10.1177/0961203310381773
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79221
dc.identifier.wosidWOS:000286180700009
dc.information.autorucMedicina;Babul M ;S/I;8096
dc.information.autorucMedicina;Bravo-Zehnder M ;S/I;1567
dc.information.autorucMedicina;Calderon J ;S/I;1001318
dc.information.autorucMedicina;Jarpa E ;S/I;159748
dc.information.autorucMedicina;Massardo L ;S/I;100068
dc.issue.numero1
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final66
dc.pagina.inicio58
dc.publisherSAGE PUBLICATIONS LTD
dc.revistaLUPUS
dc.rightsacceso restringido
dc.subjectautoantibodies
dc.subjectmental disorders
dc.subjectnervous system
dc.subjectsystemic lupus erythematosus
dc.subjectP-PROTEIN ANTIBODIES
dc.subjectNEUROPSYCHIATRIC SYNDROMES
dc.subjectRHEUMATOID-ARTHRITIS
dc.subjectINCEPTION COHORT
dc.subjectPSYCHIATRIC MANIFESTATIONS
dc.subjectDEPRESSIVE SYMPTOMS
dc.subjectPREVALENCE
dc.subjectCLASSIFICATION
dc.subjectCOLLEGE
dc.subjectMINI
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCommon mental disorders and psychological distress in systemic lupus erythematosus are not associated with disease activity
dc.typeartículo
dc.volumen20
sipa.codpersvinculados8096
sipa.codpersvinculados1567
sipa.codpersvinculados1001318
sipa.codpersvinculados159748
sipa.codpersvinculados100068
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Common mental disorders and psychological distress in systemic lupus erythematosus are not associated with disease activity.pdf
Size:
2.98 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas