Quantitative cellular automaton model for biofilms

Simple item page
dc.contributor.authorPizarro, G
dc.contributor.authorGriffeath, D
dc.contributor.authorNoguera, DR
dc.date.accessioned2024-01-10T13:16:55Z
dc.date.available2024-01-10T13:16:55Z
dc.date.issued2001
dc.description.abstractA fully quantitative cellular automaton (CA) biofilm model was developed. The model describes substrate and biomass as discrete particles existing and interacting in a specified physical domain. Substrate particles move by random walks, simulating molecular diffusion. Microbial particles grow attached to a surface or to other microbial particles, consume substrate particles, and duplicate if a sufficient amount of substrate is consumed. The dynamics of the system are simulated using stochastic processes that represent the occurrence of specific events, such as substrate diffusion, substrate utilization, biofilm growth, and biofilm decay and detachment. The ability of the CA model to predict substrate gradients and fluxes was evaluated by comparing model simulations to predictions from a traditional differential equations model. One and 2D CA models were evaluated. In general, CA model predictions of steady-state flux, biofilm thickness, and substrate gradients inside the biofilm fitted well the differential equations model results; the 2D model had a better agreement at high substrate concentrations. Fully quantitative CA biofilm models offer an alternative approach to simulate biofilm activity and development. Specific advantages of CA modeling include the ability to simulate growth of heterogeneous biofilms with irregular boundary conditions, and the possibility of developing computationally efficient parallel processing algorithms for the quantitative simulation of biofilms in two and three dimensions.
dc.fechaingreso.objetodigital2024-04-25
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1061/(ASCE)0733-9372(2001)127:9(782)
dc.identifier.issn0733-9372
dc.identifier.urihttps://doi.org/10.1061/(ASCE)0733-9372(2001)127:9(782)
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/78623
dc.identifier.wosidWOS:000170511500005
dc.information.autorucIngeniería;Pizarro G;S/I;83223
dc.issue.numero9
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final789
dc.pagina.inicio782
dc.publisherASCE-AMER SOC CIVIL ENGINEERS
dc.revistaJOURNAL OF ENVIRONMENTAL ENGINEERING-ASCE
dc.rightsacceso restringido
dc.subjectDIFFUSION-LIMITED AGGREGATION
dc.subjectSIMULATION
dc.subjectEQUATION
dc.subjectGROWTH
dc.subjectFILMS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleQuantitative cellular automaton model for biofilms
dc.typeartículo
dc.volumen127
sipa.codpersvinculados83223
sipa.indexWOS
sipa.trazabilidadCarga SIPA;09-01-2024
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
2024-04-25. Quantitative cellular automaton model for biofilms.pdf
Size:
2.87 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas