Whole-heart non-rigid motion corrected coronary MRA with autofocus virtual 3D iNAV

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dc.contributor.authorSchneider, Alina
dc.contributor.authorCruz, Gastao
dc.contributor.authorMunoz, Camila
dc.contributor.authorHajhosseiny, Reza
dc.contributor.authorKuestner, Thomas
dc.contributor.authorKunze, Karl P.
dc.contributor.authorNeji, Radhouene
dc.contributor.authorBotnar, Rene M.
dc.contributor.authorPrieto, Claudia
dc.date.accessioned2024-01-10T13:44:55Z
dc.date.available2024-01-10T13:44:55Z
dc.date.issued2022
dc.description.abstractPurpose: Respiratory motion-corrected coronary MR angiography (CMRA) has shown promise for assessing coronary disease. By incorporating coronal 2D image navigators (iNAVs), respiratory motion can be corrected for in a beat-to-beat basis using translational correction in the foot-head (FH) and right-left (RL) directions and in a bin-to-bin basis using non-rigid motion correction addressing the remaining FH, RL and anterior-posterior (AP) motion. However, with this approach beat-to-beat AP motion is not corrected for. In this work we investigate the effect of remaining beat-to-beat AP motion and propose a virtual 3D iNAV that exploits autofocus motion correction to enable beat-to-beat AP and improved RL intra-bin motion correction. Methods: Free-breathing 3D whole-heart CMRA was acquired using a 3-fold undersampled variable-density Cartesian trajectory. Beat-to-beat 3D translational respiratory motion was estimated from the 2D iNAVs in FH and RL directions, and in AP direction with autofocus assuming a linear relationship between FH and AP movement of the heart. Furthermore, motion in RL was also refined using autofocus. This virtual 3D (v3D) iNAV was incorporated in a non-rigid motion correction (NRMC) framework. The proposed approach was tested in 12 cardiac patients, and visible vessel length and vessel sharpness for the right (RCA) and left (LAD) coronary arteries were compared against 2D iNAV-based NRMC. Results: Average vessel sharpness and length in v3D iNAV NRMC was improved compared to 2D iNAV NRMC (vessel sharpness: RCA: 56 +/- 1% vs 52 +/- 11%, LAD: 49 +/- 8% vs 49 +/- 7%; visible vessel length: RCA: 5.98 +/- 1.37 cm vs 5.81 +/- 1.62 cm, LAD: 5.95 +/- 1.85 cm vs 4.83 +/- 1.56 cm), however these improvements were not statistically significant. Conclusion: The proposed virtual 3D iNAV NRMC reconstruction further improved NRMC CMRA image quality by reducing artefacts arising from residual AP motion, however the level of improvement was subject-dependent.
dc.description.funderEPSRC
dc.description.funderNational Institute for Health Research (NIHR) Cardiovascular Health Technology Cooperative (HTC)
dc.description.funderBiomedical Research Centre based at Guy's and St. Thomas'NHS Foundation Trust and King's College London
dc.description.funderWellcome Trust
dc.fechaingreso.objetodigital03-04-2024
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.mri.2022.01.007
dc.identifier.eissn1873-5894
dc.identifier.issn0730-725X
dc.identifier.pubmedidMEDLINE:34999163
dc.identifier.urihttps://doi.org/10.1016/j.mri.2022.01.007
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/78957
dc.identifier.wosidWOS:000747904600004
dc.information.autorucFacultad de Ingeniería; Prieto Vasquez, Claudia Del Carmen; S/I; 14195
dc.language.isoen
dc.nota.accesocontenido completo
dc.pagina.final176
dc.pagina.inicio169
dc.publisherELSEVIER SCIENCE INC
dc.revistaMAGNETIC RESONANCE IMAGING
dc.rightsacceso abierto
dc.subjectRespiratory motion
dc.subjectCMRA
dc.subjectWhole heart
dc.subjectAutofocus
dc.subjectNon -rigid motion correction
dc.subjectMAGNETIC-RESONANCE ANGIOGRAPHY
dc.subjectIMAGE-BASED NAVIGATORS
dc.subjectRESPIRATORY MOTION
dc.subjectDEFORMATION
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleWhole-heart non-rigid motion corrected coronary MRA with autofocus virtual 3D iNAV
dc.typeartículo
dc.volumen87
sipa.codpersvinculados14195
sipa.indexWOS
sipa.trazabilidadCarga SIPA;09-01-2024
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