Surgery for high-grade gliomas in a developing country: survival estimation using a simple stratification system

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dc.contributor.authorLorenzoni, Jose
dc.contributor.authorTorrico, Alejandro
dc.contributor.authorVillanueva, Pablo
dc.contributor.authorGederlini, Alessandra
dc.contributor.authorTorrealba, Gonzalo
dc.date.accessioned2024-01-10T14:21:47Z
dc.date.available2024-01-10T14:21:47Z
dc.date.issued2008
dc.description.abstractBackground: In spite of great technological advances in diagnostic and therapeutic tools, Survival in patients with HGG has not changed significantly in the last years. Judicious management in each case needs Survival estimation after surgery. We used a simple stratification system evaluating the histology, patient's age, and the KPS.
dc.description.abstractMethods: We retrospectively made an analysis of survival in 103 patients with HGG operated in a 10-year period (1990-1999). Three significant prognostic variables were studied: histology, patient's age, and KPS. The BS-MG was calculated, adding the partial score (0 or 1) obtained for each variable. This score ranges from 0 (worse condition) to 3 (best condition).
dc.description.abstractResults: Overall, MS was 12 months. For glioblastoma multiforme, AA, and ODS, it was 10, 20, and 19 months, respectively (P = .0001). Patients 44 years old or younger had an MS of 28 months, higher than 10 months for patients older than 45 years (P < .0001). Median Survival was 20 months for patients with KPS 80 or higher, and 9 months for those with KPS 70 or lower (P =.02). It was 3.5 months in patients with BS-MG = 0, 9 months for BS-MG = 1, 22 months for BS-MG = 2, and 55 months for BS-MG = 3 (P < .0001.).
dc.description.abstractConclusions: Survival presented here is comparable with those previously reported despite lacking the most sophisticated surgical technique. The stratification score that includes the 3 most important variables for survival seems to be simple and reliable for survival estimation. (C) 2008 Elsevier Inc. All rights reserved.
dc.fechaingreso.objetodigital11-04-2024
dc.format.extent7 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.surneu.2007.08.004
dc.identifier.issn0090-3019
dc.identifier.pubmedidMEDLINE:18440602
dc.identifier.urihttps://doi.org/10.1016/j.surneu.2007.08.004
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/79778
dc.identifier.wosidWOS:000261701000006
dc.information.autorucMedicina;Gederlini A;S/I;5555
dc.information.autorucMedicina;Lorenzoni J;S/I;80739
dc.information.autorucMedicina;Torrealba G;S/I;98641
dc.information.autorucMedicina;Torrico A;S/I;129236
dc.information.autorucMedicina;Villanueva P;S/I;5368
dc.issue.numero6
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final597
dc.pagina.inicio591
dc.publisherELSEVIER SCIENCE INC
dc.revistaSURGICAL NEUROLOGY
dc.rightsacceso restringido
dc.subjectHigh-grade gliomas
dc.subjectSurvival
dc.subjectPrognostic
dc.subjectSurgery
dc.subjectGLIOBLASTOMA-MULTIFORME
dc.subjectMULTIVARIATE-ANALYSIS
dc.subjectPROGNOSTIC-FACTORS
dc.subjectMALIGNANT GLIOMA
dc.subjectRESECTION
dc.subjectMANAGEMENT
dc.subjectEXTENT
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleSurgery for high-grade gliomas in a developing country: survival estimation using a simple stratification system
dc.typeartículo
dc.volumen70
sipa.codpersvinculados5555
sipa.codpersvinculados80739
sipa.codpersvinculados98641
sipa.codpersvinculados129236
sipa.codpersvinculados5368
sipa.indexWOS
sipa.trazabilidadCarga SIPA;09-01-2024
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