Frequency of Self-Reported COPD Exacerbation and Airflow Obstruction in Five Latin American Cities The Proyecto Latinoamericano de Investigacion en Obstruccion Pulmonar (PLATINO) Study

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dc.contributor.authorMontes de Oca, Maria
dc.contributor.authorTalamo, Carlos
dc.contributor.authorHalbert, Ronald J.
dc.contributor.authorPerez Padilla, Rogelio
dc.contributor.authorVictorina Lopez, Maria
dc.contributor.authorMuino, Adriana
dc.contributor.authorJardim, Jose Roberto B.
dc.contributor.authorValdivia, Gonzalo
dc.contributor.authorPertuze, Julio
dc.contributor.authorMoreno, Dolores
dc.contributor.authorMenezes, Ana Maria B.
dc.date.accessioned2024-01-10T12:39:05Z
dc.date.available2024-01-10T12:39:05Z
dc.date.issued2009
dc.description.abstractBackground: Recurrent exacerbations are common in COPD patients. Limited information exists regarding exacerbation frequency in COPD patients from epidemiologic studies. We examined the frequency of self-reported exacerbations and the factors influencing exacerbation frequency among COPD patients in a population-based study conducted in Latin America.
dc.description.abstractMethods: We used a post-bronchodilator FEV1/FVC ratio of < 0.70 to define COPD. Exacerbation was self-reported and defined by symptoms (deterioration of breathing symptoms that affected usual daily activities or caused missed work).
dc.description.abstractResults.: Spirometry was performed in 5,314 subjects. There were 759 subjects with airflow limitation; of these, 18.2% reported ever having had an exacerbation, 7.9% reported having an exacerbation, and 6.2% reported having an exacerbation requiting at least a doctor visit within the past year. The proportion of individuals with an exacerbation significantly increased by Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages, from 4.2% in stage I to 28.9% in stages 3 and 4. The self-reported exacerbation rate was 0.58 exacerbations per year. The rate of exacerbations requiring at least a doctor visit and length of stay in hospital due to exacerbations also increased as COPD severity progressed. The factors associated with having an exacerbation in the past year were dyspnea, prior asthma diagnosis, receiving any respiratory therapy, and disease severity of GOLD stages 3 and 4.
dc.description.abstractConclusions: The proportion of individuals with airflow limitation and self-reported exacerbation increases as the disease severity progresses. Dyspnea, prior asthma diagnosis, receiving any respiratory therapy, and more severe obstruction were significantly associated with having an exacerbation in the past year. (CHEST 2009; 136:71-78)
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1378/chest.08-2081
dc.identifier.issn0012-3692
dc.identifier.pubmedidMEDLINE:19349388
dc.identifier.urihttps://doi.org/10.1378/chest.08-2081
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77144
dc.identifier.wosidWOS:000267779000013
dc.information.autorucMedicina;Pertuze J ;S/I;99166
dc.information.autorucMedicina;Valdivia G;S/I;57007
dc.issue.numero1
dc.language.isoen
dc.nota.accesoSin adjunto
dc.pagina.final78
dc.pagina.inicio71
dc.publisherELSEVIER SCIENCE BV
dc.revistaCHEST
dc.rightsregistro bibliográfico
dc.subjectDISEASE EXACERBATION
dc.subjectHOSPITAL ADMISSION
dc.subjectRISK-FACTORS
dc.subjectINFLAMMATION
dc.subjectPOPULATION
dc.subjectPREVENTION
dc.subjectPREVALENCE
dc.subjectDIAGNOSIS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleFrequency of Self-Reported COPD Exacerbation and Airflow Obstruction in Five Latin American Cities The Proyecto Latinoamericano de Investigacion en Obstruccion Pulmonar (PLATINO) Study
dc.typeartículo
dc.volumen136
sipa.codpersvinculados99166
sipa.codpersvinculados57007
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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