Changes in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries

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dc.catalogadoraba
dc.contributor.authorCalvert, C.
dc.contributor.authorBrockway, M.M.
dc.contributor.authorZoega, H.
dc.contributor.authorMiller, J.E.
dc.contributor.authorBeen, J.V.
dc.contributor.authorAmegah, A.K.
dc.contributor.authorRacine-Poon, A.
dc.contributor.authorOskoui, S.E.
dc.contributor.authorAbok, I.I.
dc.contributor.authorAghaeepour, N.
dc.contributor.authorAkwaowo, C.D.
dc.contributor.authorAlshaikh, B.N.
dc.contributor.authorAyede, A.I.
dc.contributor.authorBacchini, F.
dc.contributor.authorBarekatain, B.
dc.contributor.authorBarnes, R.
dc.contributor.authorBebak, K.
dc.contributor.authorBerard, A.
dc.contributor.authorBhutta, Z.A.
dc.contributor.authorBrook, J.R.
dc.contributor.authorBryan, L.R.
dc.contributor.authorCajachagua-Torres, K.N.
dc.contributor.authorCampbell-Yeo, M.
dc.contributor.authorChu, D.-T.
dc.contributor.authorConnor, K.L.
dc.contributor.authorCornette, L.
dc.contributor.authorCortés, S.
dc.contributor.authorDaly, M.
dc.contributor.authorDebauche, C.
dc.contributor.authorDedeke, I.O.F.
dc.contributor.authorEinarsdóttir, K.
dc.contributor.authorEngjom, H.
dc.contributor.authorEstrada-Gutierrez, G.
dc.contributor.authorFantasia, I.
dc.contributor.authorFiorentino, N.M.
dc.contributor.authorFranklin, M.
dc.contributor.authorFraser, A.
dc.contributor.authorGachuno, O.W.
dc.contributor.authorGallo, L.A.
dc.contributor.authorGissler, M.
dc.contributor.authorHåberg, S.E.
dc.contributor.authorHabibelahi, A.
dc.contributor.authorHäggström, J.
dc.contributor.authorHookham, L.
dc.contributor.authorHui, L.
dc.contributor.authorHuicho, L.
dc.contributor.authorHunter, K.J.
dc.contributor.authorHuq, S.
dc.contributor.authorKc, A.
dc.contributor.authorKadambari, S.
dc.contributor.authorKelishadi, R.
dc.contributor.authorKhalili, N.
dc.contributor.authorKippen, J.
dc.contributor.authorLe Doare, K.
dc.contributor.authorLlorca, J.
dc.contributor.authorMagee, L.A.
dc.contributor.authorMagnus, M.C.
dc.contributor.authorMan, K.K.C.
dc.contributor.authorMburugu, P.M.
dc.contributor.authorMediratta, R.P.
dc.contributor.authorMorris, A.D.
dc.contributor.authorMuhajarine, N.
dc.contributor.authorMulholland, R.H.
dc.contributor.authorBonnard, L.N.
dc.contributor.authorNakibuuka, V.
dc.contributor.authorNassar, N.
dc.contributor.authorNyadanu, S.D.
dc.contributor.authorOakley, L.
dc.contributor.authorOladokun, A.
dc.contributor.authorOlayemi, O.O.
dc.contributor.authorOlutekunbi, O.A.
dc.contributor.authorOluwafemi, R.O.
dc.contributor.authorOgunkunle, T.O.
dc.contributor.authorOrton, C.
dc.contributor.authorÖrtqvist, A.K.
dc.contributor.authorOuma, J.
dc.contributor.authorOyapero, O.
dc.contributor.authorPalmer, K.R.
dc.contributor.authorPedersen, L.H.
dc.contributor.authorPereira, G.
dc.contributor.authorPereyra, I.
dc.contributor.authorPhilip, R.K.
dc.contributor.authorPruski, D.
dc.contributor.authorPrzybylski, M.
dc.contributor.authorQuezada-Pinedo, H.G.
dc.contributor.authorRegan, A.K.
dc.contributor.authorRhoda, N.R.
dc.contributor.authorRihs, T.A.
dc.contributor.authorRiley, T.
dc.contributor.authorRocha, T.A.H.
dc.contributor.authorRolnik, D.L.
dc.contributor.authorSaner, C.
dc.contributor.authorSchneuer, F.J.
dc.contributor.authorSouter, V.L.
dc.contributor.authorStephansson, O.
dc.contributor.authorSun, S.
dc.contributor.authorSwift, E.M.
dc.contributor.authorSzabó, M.
dc.contributor.authorTemmerman, M.
dc.contributor.authorTooke, L.
dc.contributor.authorUrquia, M.L.
dc.contributor.authorvon Dadelszen, P.
dc.contributor.authorWellenius, G.A.
dc.contributor.authorWhitehead, C.
dc.contributor.authorWong, I.C.K.
dc.contributor.authorWood, R.
dc.contributor.authorWróblewska-Seniuk, K.
dc.contributor.authorYeboah-Antwi, K.
dc.contributor.authorYilgwan, C.S.
dc.contributor.authorZawiejska, A.
dc.contributor.authorSheikh, A.
dc.contributor.authorRodriguez, N.
dc.contributor.authorBurgner, D.
dc.contributor.authorStock, S.J.
dc.contributor.authorAzad, M.B.
dc.date.accessioned2024-01-17T19:36:05Z
dc.date.available2024-01-17T19:36:05Z
dc.date.issued2023
dc.description.abstractPreterm birth (PTB) is the leading cause of infant mortality worldwide. Changes in PTB rates, ranging from −90% to +30%, were reported in many countries following early COVID-19 pandemic response measures (‘lockdowns’). It is unclear whether this variation reflects real differences in lockdown impacts, or perhaps differences in stillbirth rates and/or study designs. Here we present interrupted time series and meta-analyses using harmonized data from 52 million births in 26 countries, 18 of which had representative population-based data, with overall PTB rates ranging from 6% to 12% and stillbirth ranging from 2.5 to 10.5 per 1,000 births. We show small reductions in PTB in the first (odds ratio 0.96, 95% confidence interval 0.95–0.98, P value <0.0001), second (0.96, 0.92–0.99, 0.03) and third (0.97, 0.94–1.00, 0.09) months of lockdown, but not in the fourth month of lockdown (0.99, 0.96–1.01, 0.34), although there were some between-country differences after the first month. For high-income countries in this study, we did not observe an association between lockdown and stillbirths in the second (1.00, 0.88–1.14, 0.98), third (0.99, 0.88–1.12, 0.89) and fourth (1.01, 0.87–1.18, 0.86) months of lockdown, although we have imprecise estimates due to stillbirths being a relatively rare event. We did, however, find evidence of increased risk of stillbirth in the first month of lockdown in high-income countries (1.14, 1.02–1.29, 0.02) and, in Brazil, we found evidence for an association between lockdown and stillbirth in the second (1.09, 1.03–1.15, 0.002), third (1.10, 1.03–1.17, 0.003) and fourth (1.12, 1.05–1.19, <0.001) months of lockdown. With an estimated 14.8 million PTB annually worldwide, the modest reductions observed during early pandemic lockdowns translate into large numbers of PTB averted globally and warrant further research into causal pathways.
dc.fechaingreso.objetodigital2024-01-19
dc.format.extent29 páginas
dc.fuente.origenORCID-ene24
dc.identifier.doi10.1038/s41562-023-01522-y
dc.identifier.eissn2397-3374
dc.identifier.urihttps://doi.org/10.1038/s41562-023-01522-y
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/80570
dc.information.autorucEscuela de Medicina; Cortes Arancibia, Sandra Isabel; 0000-0003-3293-1419; 1005970
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final544
dc.pagina.inicio529
dc.revistaNature Human Behaviour
dc.rightsacceso abierto
dc.rights.licenseCC BY 4.0 DEED Attribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleChanges in preterm birth and stillbirth during COVID-19 lockdowns in 26 countries
dc.typeartículo
dc.volumen7
sipa.codpersvinculados1005970
sipa.trazabilidadORCID;2024-01-08
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