Sex differences in mortality in patients with COPD

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dc.contributor.authorde Torres, J. P.
dc.contributor.authorCote, C. G.
dc.contributor.authorLopez, M. V.
dc.contributor.authorCasanova, C.
dc.contributor.authorDiaz, O.
dc.contributor.authorMarin, J. M.
dc.contributor.authorPinto Plata, V.
dc.contributor.authorde Oca, M. M.
dc.contributor.authorNekach, H.
dc.contributor.authorDordelly, L. J.
dc.contributor.authorAguirre Jaime, A.
dc.contributor.authorCelli, B. R.
dc.date.accessioned2024-01-10T13:17:35Z
dc.date.available2024-01-10T13:17:35Z
dc.date.issued2009
dc.description.abstractLittle is known about survival and clinical prognostic factors in females with chronic obstructive pulmonary disease (COPD). The aim of the present study was to determine the survival difference between males and females with COPD and to compare the value of the different prognostic factors for the disease.
dc.description.abstractIn total, 265 females and 272 males with COPD matched at baseline by BODE (body mass index, airflow obstruction, dyspnoea, exercise capacity) and American Thoracic Society/European Respiratory Society/Global Initiative of Chronic Obstructive Lung Disease criteria were prospectively followed. Demographics, lung function, St George's Respiratory Questionnaire, BODE index, the components of the BODE index and comorbidity were determined. Survival was documented and sex differences were determined using Kaplan-Meier analysis. The strength of the association of the studied variables with mortality was determined using multivariate and receiver operating curves analysis.
dc.description.abstractAll-cause (40 versus 18%) and respiratory mortality (24 versus 10%) were higher in males than females. Multivariate analysis identified the BODE index in females and the BODE index and Charlson comorbidity score in males as the best predictors of mortality. The area under the curve of the BODE index was a better predictor of mortality than the forced expiratory volume in one second for both sexes.
dc.description.abstractAt similar chronic obstructive pulmonary disease severity by BODE index and forced expiratory volume in one second, females have significantly better survival than males. For both sexes the BODE index is a better predictor of survival than the forced expiratory volume in one second.
dc.fechaingreso.objetodigital2024-05-15
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1183/09031936.00096108
dc.identifier.eissn1399-3003
dc.identifier.issn0903-1936
dc.identifier.pubmedidMEDLINE:19047315
dc.identifier.urihttps://doi.org/10.1183/09031936.00096108
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/78674
dc.identifier.wosidWOS:000263942400013
dc.information.autorucMedicina;Diaz O;S/I;78564
dc.issue.numero3
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final535
dc.pagina.inicio528
dc.publisherEUROPEAN RESPIRATORY SOC JOURNALS LTD
dc.revistaEUROPEAN RESPIRATORY JOURNAL
dc.rightsacceso restringido
dc.subjectBODE (body mass index, airflow obstruction, dyspnoea, exercise capacity) index
dc.subjectchronic obstructive pulmonary disease
dc.subjectmortality
dc.subjectsex
dc.subjectOBSTRUCTIVE PULMONARY-DISEASE
dc.subjectTERM OXYGEN-THERAPY
dc.subjectBODY-MASS INDEX
dc.subjectQUALITY-OF-LIFE
dc.subjectGENDER
dc.subjectSURVIVAL
dc.subjectDYSPNEA
dc.subjectRISK
dc.subjectHOSPITALIZATION
dc.subjectEMPHYSEMA
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleSex differences in mortality in patients with COPD
dc.typeartículo
dc.volumen33
sipa.codpersvinculados78564
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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