Early detection of cervical cancer in Chile: time for change

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dc.contributor.authorLeniz Martelli, Javiera
dc.contributor.authorVan De Wyngard, Vanessa
dc.contributor.authorLagos, Marcela
dc.contributor.authorIsabel Barriga, Maria
dc.contributor.authorPuschel Illanes, Klaus
dc.contributor.authorFerreccio Readi, Catterina
dc.date.accessioned2024-01-10T13:47:47Z
dc.date.available2024-01-10T13:47:47Z
dc.date.issued2014
dc.description.abstractMortality rates for cervical cancer (CC) in Chile are higher than those of developed countries and it has an unequal socioeconomic distribution. The recognition of human papilloma virus (HPV) as the causal agent of cervical cancer in the early 80's changed the prevention paradigms. Current goals are to prevent HPV infection by vaccination before the onset of sexual activity and to detect HPV infection in women older than 30 years. This article reviews CC prevention and early detection methods, discusses relevant evidence to support a change in Chile and presents an innovation proposal. A strategy of primary screening based on HPV detection followed by triage of HPV-positive women by colposcopy in primary care or by cytological or molecular reflex testing is proposed. Due to the existence in Chile of a well-organized nationwide CC prevention program, the replacement of a low-sensitivity screening test such as the Papanicolau test with a highly sensitive one such as HPV detection, could quickly improve the effectiveness of the program. The program also has a network of personnel qualified to conduct naked-eye inspections of the cervix, who could easily be trained to perform triage colposcopy. The incorporation of new prevention strategies could reduce the deaths of Chilean women and correct inequities.
dc.fechaingreso.objetodigital2024-06-18
dc.format.extent9 páginas
dc.fuente.origenWOS
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:25424677
dc.identifier.urihttp://dx.doi.org/10.4067/S0034-98872014000800012
dc.identifier.wosidWOS:000342602500012
dc.information.autorucMedicina;Barriga M;S/I;846
dc.information.autorucMedicina;Ferreccio Readi C;S/I;99684
dc.information.autorucMedicina;Lagos M;S/I;72982
dc.information.autorucMedicina;Leniz Martelli J;S/I;16027
dc.information.autorucMedicina;Puschel Illanes K;S/I;83957
dc.information.autorucMedicina;Van De Wyngard V;S/I;17770
dc.issue.numero8
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final1055
dc.pagina.inicio1047
dc.publisherSOC MEDICA SANTIAGO
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsacceso abierto
dc.subjectDelivery of health care
dc.subjectEarly detection of cancer
dc.subjectHuman papiloma virus
dc.subjectUterine cervical neoplasms
dc.subjectHUMAN-PAPILLOMAVIRUS
dc.subjectSCREENING-PROGRAMS
dc.subjectCOST-EFFECTIVENESS
dc.subjectLATIN-AMERICA
dc.subjectWOMEN
dc.subjectSELF
dc.subjectIMMUNOGENICITY
dc.subjectPREVALENCE
dc.subjectINFECTION
dc.subjectSANTIAGO
dc.subject.ods03 Good Health and Well-being
dc.subject.ods05 Gender Equality
dc.subject.odspa03 Salud y bienestar
dc.subject.odspa05 Igualdad de género
dc.titleEarly detection of cervical cancer in Chile: time for change
dc.typeartículo
dc.volumen142
sipa.codpersvinculados846
sipa.codpersvinculados99684
sipa.codpersvinculados72982
sipa.codpersvinculados16027
sipa.codpersvinculados83957
sipa.codpersvinculados17770
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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