Chronic Liver Failure and Concomitant Distant Infections Are Associated With High Rates of Neurological Involvement in Pyogenic Spinal Infections

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dc.contributor.authorUrrutia, Julio
dc.contributor.authorBono, Christopher M.
dc.contributor.authorMery, Pablo
dc.contributor.authorRojas, Claudio
dc.contributor.authorGana, Natalia
dc.contributor.authorCampos, Mauricio
dc.date.accessioned2024-01-10T12:04:38Z
dc.date.available2024-01-10T12:04:38Z
dc.date.issued2009
dc.description.abstractStudy Design. A retrospective study of a consecutive series of all patients with pyogenic spinal infections treated at a single institution over a 10-year period.
dc.description.abstractObjective. To investigate risk factors for neurologic impairment with pyogenic spinal infections.
dc.description.abstractSummary of Background Data. Pyogenic spinal infections are frequently associated with neurologic deficit at the time of initial diagnosis. Current evidence suggests that advanced age, diabetes mellitus, rheumatoid arthritis, systemic corticosteroid therapy, impaired immune status, infection with Staphylococcus aureus, and more proximal infections are risk factors for neurologic involvement. To the authors' knowledge, however, the influence of chronic liver failure or concomitant nonspinal infection has not been previously investigated.
dc.description.abstractMethods. A review of all patients discharged with a diagnosis of pyogenic spinal infection was performed. Data were collected, including age, sex, site of infection, degree of neurologic impairment, bacterial organism isolated, and various medical comorbidities such as diabetes mellitus, rheumatoid arthritis, chronic corticosteroid therapy, chronic liver failure, chronic renal failure, smoking, human immunodeficiency virus infection, intravenous drug abuse, cancer, cardiac disease, and the presence of a distant, nonspinal site of infection.
dc.description.abstractResults. Fifty-five consecutive patients with pyogenic spinal infections were identified. Statistical analysis demonstrated that the presence of an epidural abscess, chronic liver failure, or a distant nonspinal infection were the only significant risk factors for neurologic involvement.
dc.description.abstractConclusion. The current data suggest that chronic liver failure and the presence of a distant nonspinal infection are possible risk factors for neurologic involvement in patients with pyogenic spinal infections. These risk factors have not been previously described. This knowledge warrants closer surveillance for neurologic deficit in patients with these conditions.
dc.fechaingreso.objetodigital2024-05-16
dc.format.extent5 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1097/BRS.0b013e3181921508
dc.identifier.eissn1528-1159
dc.identifier.issn0362-2436
dc.identifier.pubmedidMEDLINE:19333086
dc.identifier.urihttps://doi.org/10.1097/BRS.0b013e3181921508
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75847
dc.identifier.wosidWOS:000265677500030
dc.information.autorucMedicina;Urrutia J ;S/I;69910
dc.issue.numero7
dc.language.isoen
dc.nota.accesocontenido parcial
dc.publisherLIPPINCOTT WILLIAMS & WILKINS
dc.revistaSPINE
dc.rightsacceso restringido
dc.subjectpyogenic spinal infections
dc.subjectneurological involvement
dc.subjectrisk factors
dc.subjectvertebral osteomyelitis
dc.subjectEPIDURAL ABSCESS
dc.subjectVERTEBRAL OSTEOMYELITIS
dc.subjectBACTERIAL-INFECTIONS
dc.subjectCLINICAL-FEATURES
dc.subjectCIRRHOSIS
dc.subjectNORFLOXACIN
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleChronic Liver Failure and Concomitant Distant Infections Are Associated With High Rates of Neurological Involvement in Pyogenic Spinal Infections
dc.typeartículo
dc.volumen34
sipa.codpersvinculados69910
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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