Treatment of thrombotic thrombocytopenic purpura with rituximab. Report of eight cases

Abstract
Thrombotic thrombocytopenic purpura, an immune/non-immune thrombotic microangiopathy (TTP/TMA) is associated with high morbidity and mortality, even with appropriate treatment. In patients refractory to standard treatment with plasmapheresis there is no certainty about the best therapeutic strategy. This report shows our experience in eight refractory patients who survived after treatment with rituximab.
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Keywords
Purpura, thrombotic thrombocytopenic, rituximab, Thrombotic microangiopathies
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