Sex-related differences in COPD in five Latin American cities: the PLATINO study

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dc.contributor.authorLopez Varela, M. V.
dc.contributor.authorMontes de Oca, M.
dc.contributor.authorHalbert, R. J.
dc.contributor.authorMuino, A.
dc.contributor.authorPerez Padilla, R.
dc.contributor.authorTalamo, C.
dc.contributor.authorJardim, J. R. B.
dc.contributor.authorValdivia, G.
dc.contributor.authorPertuze, J.
dc.contributor.authorMoreno, D.
dc.contributor.authorMenezes, A. M. B.
dc.contributor.authorPLATINO Team
dc.date.accessioned2024-01-10T12:42:34Z
dc.date.available2024-01-10T12:42:34Z
dc.date.issued2010
dc.description.abstractThere is evidence to suggest sex differences exists in chronic obstructive pulmonary disease (COPD) clinical expression. We investigated sex differences in health status perception, dyspnoea and physical activity, and factors that explain these differences using an epidemiological sample of subjects with and without COPD.
dc.description.abstractPLATINO is a cross-sectional, population-based study. We defined COPD as post-bronchodilator forced expiratory volume in 1 s/forced vital capacity ratio <0.70, and evaluated health status perception (Short Form (SF)-12 questionnaire) and dyspnoea (Medical Research Council scale).
dc.description.abstractAmong 5,314 subjects, 759 (362 females) had COPD and 4,555 (2,850 females) did not. In general, females reported more dyspnoea and physical limitation than males. 54% of females without COPD reported a dyspnoea score >= 2 versus 35% of males. A similar trend was observed in females with COPD (63% versus 44%). In the entire study population, female sex was a factor explaining dyspnoea (OR 1.60, 95% CI 1.40-1.84) and SF-12 physical score (OR -1.13, 95% CI -1.56- -0.71). 40% of females versus 28% of males without COPD reported their general health status as fair-to-poor. Females with COPD showed a similar trend (41% versus 34%). Distribution of COPD severity was similar between sexes, but currently smoking females had more severe COPD than currently smoking males.
dc.description.abstractThere are important sex differences in the impact that COPD has on the perception of dyspnoea, health status and physical activity limitation.
dc.description.funderBoehringer Ingelheim GmbH (Ingelheim, Germany)
dc.description.funderAsociacion Latinoamericana de Torax (ALAT)
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1183/09031936.00165409
dc.identifier.eissn1399-3003
dc.identifier.issn0903-1936
dc.identifier.pubmedidMEDLINE:20378599
dc.identifier.urihttps://doi.org/10.1183/09031936.00165409
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77522
dc.identifier.wosidWOS:000283669700012
dc.information.autorucMedicina; Pertuze J;S/I;99166
dc.information.autorucMedicina;Valdivia G;S/I;57007
dc.issue.numero5
dc.language.isoen
dc.nota.accesoSin adjunto
dc.pagina.final1041
dc.pagina.inicio1034
dc.publisherEUROPEAN RESPIRATORY SOC JOURNALS LTD
dc.revistaEUROPEAN RESPIRATORY JOURNAL
dc.rightsregistro bibliográfico
dc.subjectChronic pulmonary disease
dc.subjectepidemiology
dc.subjecthealth status
dc.subjectsex
dc.subjectsusceptibility
dc.subjectOBSTRUCTIVE PULMONARY-DISEASE
dc.subjectAIR-FLOW OBSTRUCTION
dc.subjectGENDER-DIFFERENCE
dc.subjectLUNG HEALTH
dc.subjectPREVALENCE
dc.subjectHYPERRESPONSIVENESS
dc.subjectCOMORBIDITIES
dc.subjectMANAGEMENT
dc.subjectMORTALITY
dc.subjectSMOKING
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleSex-related differences in COPD in five Latin American cities: the PLATINO study
dc.typeartículo
dc.volumen36
sipa.codpersvinculados99166
sipa.codpersvinculados57007
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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