Eccentric Contractions of the Diaphragm During Mechanical Ventilation

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dc.catalogadorgrr
dc.contributor.authorGarcía Valdés, Patricio Hernán
dc.contributor.authorFernandez Mincone, Tiziana Rita
dc.contributor.authorJalil Contreras, Yorschua Frederick
dc.contributor.authorPeñailillo, Luis
dc.contributor.authorDamiani Rebolledo, L. Felipe
dc.date.accessioned2024-10-24T20:27:11Z
dc.date.available2024-10-24T20:27:11Z
dc.date.issued2023
dc.description.abstractDiaphragm dysfunction is a highly prevalent phenomenon in patients receiving mechanical ventilation, mainly due to ventilatory over-assistance and the development of diaphragm disuse atrophy. Promoting diaphragm activation whenever possible and facilitating an adequate interaction between the patient and the ventilator is encouraged at the bedside to avoid myotrauma and further lung injury. Eccentric contractions of the diaphragm are defined as muscle activation while muscle fibers are lengthening within the exhalation phase. There is recent evidence that suggests that eccentric activation of the diaphragm is very frequent and may occur during post-inspiratory activity or under different types of patient-ventilator asynchronies, which include ineffective efforts, premature cycling, and reverse triggering. The consequences of this eccentric contraction of the diaphragm may have opposite effects, depending on the level of breathing effort. For instance, during high or excessive effort, eccentric contractions can result in diaphragm dysfunction and injured muscle fibers. Conversely, when eccentric contractions of the diaphragm occur along with low breathing effort, a preserved diaphragm function, better oxygenation, and more aerated lung tissue are observed. Despite this controversial evidence, evaluating the level of breathing effort at the bedside seems crucial and is highly recommended to optimize ventilatory therapy. The impact of eccentric contractions of the diaphragm on the patient's outcome remains to be elucidated.
dc.fuente.origenWOS
dc.identifier.doi10.4187/respcare.11040
dc.identifier.eissn1943-3654
dc.identifier.issn0020-1324
dc.identifier.pubmedid37402586
dc.identifier.scopusidSCOPUS_ID:2-s2.0-85169594573
dc.identifier.urihttps://doi.org/10.4187/respcare.11040
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/88361
dc.identifier.wosidWOS:001162438800018
dc.information.autorucDepartamento de Ciencias de la Salud; García Valdés, Patricio Hernán; S/I; 1006675
dc.information.autorucDepartamento de Ciencias de la Salud; Fernandez Mincone, Tiziana Rita; 0000-0002-0865-9198; 205468
dc.information.autorucDepartamento de Ciencias de la Salud; Jalil Contreras, Yorschua Frederick; 0000-0002-4993-7158; 1079709
dc.information.autorucDepartamento de Ciencias de la Salud; Damiani Rebolledo, L. Felipe; 0000-0002-8338-0488; 237645
dc.issue.numero12
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final1762
dc.pagina.inicio1757
dc.revistaRespiratory Care
dc.rightsacceso restringido
dc.subjectDiaphragm
dc.subjectVentilator weaning
dc.subjectReverse triggering
dc.subjectReverse trigger
dc.subjectEccentric contraction
dc.subjectMechanical ventilation
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleEccentric Contractions of the Diaphragm During Mechanical Ventilation
dc.typeartículo
dc.volumen68
sipa.codpersvinculados1006675
sipa.codpersvinculados205468
sipa.codpersvinculados1079709
sipa.codpersvinculados237645
sipa.trazabilidadWOS;2024-03-30
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