Color Doppler Ultrasound Assessment of Subclinical Activity With Scoring of Morphea

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dc.catalogadorjlo
dc.contributor.authorParra Cares, Julio Alejandro
dc.contributor.authorWortsman Canovas, Ximena Loreto
dc.contributor.authorAlfaro Sepúlveda, Daniela Alejandra
dc.contributor.authorMellado Francisco, Gonzalo
dc.contributor.authorRamírez Cornejo, Cristian Alejandro
dc.contributor.authorVera Kellet, Cristián Andrés
dc.date.accessioned2023-08-07T20:15:08Z
dc.date.available2023-08-07T20:15:08Z
dc.date.issued2023
dc.description.abstractBackground: Detection of activity in morphea is paramount for adequately managing the disease. Subclinical ultrasoundinvolvement on inactive lesions or healthy skin areas adjacent to morphea has not been described to date.Objectives: The study aimed to detect morphea’s subclinical activity by Color Doppler ultrasound not identified with theclinical scorings.Materials & methods: This cross-sectional retrospective study was done from January 2014 to July 2019 in patients witha clinicopathological diagnosis of morphea. The modified Localized Scleroderma Skin Severity Index (mLoSSI) and TheUltrasound Morphea Activity Score (US-MAS) were used to correlate clinical and subclinical activity.Results: A total of 36 patients met the inclusion criteria. 54% of cases presented subclinical activity in areas adjacent to theclinically active lesion, 23% in nonadjacent regions, and 23% demonstrated activity at a clinically inactive lesion site.100% of patients with morphea “en coup de sabre” involving the frontal region of the face concomitantly presented bothsubclinical activities of morphea on the frontal facial region and the scalp following the same axis.A positive relationship was observed between the degree of clinical activity measured by mLoSSI and US-MAS scoring.The main limitations of our study were the low number of patients and the inability to detect alterations < 0.1 mm.Conclusions: Subclinical activity is frequent in morphea, can extend beyond the lesional areas, including apparently noninvolved adjacent and distant corporal regions, and can be detected by color Doppler ultrasound.
dc.fechaingreso.objetodigital2023-08-07
dc.format.extent7 páginas
dc.fuente.origenORCID
dc.identifier.doi10.1177/12034754231191474
dc.identifier.eissn1615-7109
dc.identifier.issn1203-4754
dc.identifier.urihttps://doi.org/10.1177/12034754231191474
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/74371
dc.information.autorucEscuela de Medicina; Parra Cares, Julio Alejandro; 0000-0003-1067-3930; 149076
dc.information.autorucEscuela de Medicina; Wortsman Canovas, Ximena Loreto; 0000-0003-3359-5023; 1043349
dc.information.autorucEscuela de Medicina; Alfaro Sepúlveda, Daniela Alejandra; 0000-0002-5747-5483; 223845
dc.information.autorucEscuela de Medicina; Ramírez Cornejo, Cristian Alejandro; S/I; 163756
dc.information.autorucEscuela de Medicina; Vera Kellet, Cristián Andrés; 0000-0001-8697-9245; 9379
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final7
dc.pagina.inicio1
dc.revistaJournal of Cutaneous Medicine and Surgery
dc.rightsacceso restringido
dc.subjectActivity
dc.subjectClinical
dc.subjectMorphea
dc.subjectLocalized scleroderma
dc.subjectSkin ultrasound
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.titleColor Doppler Ultrasound Assessment of Subclinical Activity With Scoring of Morphea
dc.typeartículo
sipa.codpersvinculados149076
sipa.codpersvinculados1043349
sipa.codpersvinculados223845
sipa.codpersvinculados163756
sipa.codpersvinculados9379
sipa.trazabilidadORCID;2023-08-07
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