3D whole-heart grey-blood late gadolinium enhancement cardiovascular magnetic resonance imaging

Simple item page
dc.contributor.authorMilotta, Giorgia
dc.contributor.authorMunoz, Camila
dc.contributor.authorKunze, Karl P.
dc.contributor.authorNeji, Radhouene
dc.contributor.authorFigliozzi, Stefano
dc.contributor.authorChiribiri, Amedeo
dc.contributor.authorHajhosseiny, R.
dc.contributor.authorMasci, Pier Giorgio
dc.contributor.authorPrieto Vásquez, Claudia
dc.contributor.authorBotnar, René Michael
dc.date.accessioned2021-06-02T13:28:11Z
dc.date.available2021-06-02T13:28:11Z
dc.date.issued2021
dc.date.updated2021-05-30T00:02:31Z
dc.description.abstractAbstract Purpose To develop a free-breathing whole-heart isotropic-resolution 3D late gadolinium enhancement (LGE) sequence with Dixon-encoding, which provides co-registered 3D grey-blood phase-sensitive inversion-recovery (PSIR) and complementary 3D fat volumes in a single scan of < 7 min. Methods A free-breathing 3D PSIR LGE sequence with dual-echo Dixon readout with a variable density Cartesian trajectory with acceleration factor of 3 is proposed. Image navigators are acquired to correct both inversion recovery (IR)-prepared and reference volumes for 2D translational respiratory motion, enabling motion compensated PSIR reconstruction with 100% respiratory scan efficiency. An intermediate PSIR reconstruction is performed between the in-phase echoes to estimate the signal polarity which is subsequently applied to the IR-prepared water volume to generate a water grey-blood PSIR image. The IR-prepared water volume is obtained using a water/fat separation algorithm from the corresponding dual-echo readout. The complementary fat-volume is obtained after water/fat separation of the reference volume. Ten patients (6 with myocardial scar) were scanned with the proposed water/fat grey-blood 3D PSIR LGE sequence at 1.5 T and compared to breath-held grey-blood 2D LGE sequence in terms of contrast ratio (CR), contrast-to-noise ratio (CNR), scar depiction, scar transmurality, scar mass and image quality. Results Comparable CRs (p = 0.98, 0.40 and 0.83) and CNRs (p = 0.29, 0.40 and 0.26) for blood-myocardium, scar-myocardium and scar-blood respectively were obtained with the proposed free-breathing 3D water/fat LGE and 2D clinical LGE scan. Excellent agreement for scar detection, scar transmurality, scar mass (bias = 0.29%) and image quality scores (from 1: non-diagnostic to 4: excellent) of 3.8 ± 0.42 and 3.6 ± 0.69 (p > 0.99) were obtained with the 2D and 3D PSIR LGE approaches with comparable total acquisition time (p = 0.29). Similar agreement in intra and inter-observer variability were obtained for the 2D and 3D acquisition respectively. Conclusion The proposed approach enabled the acquisition of free-breathing motion-compensated isotropic-resolution 3D grey-blood PSIR LGE and fat volumes. The proposed approach showed good agreement with conventional 2D LGE in terms of CR, scar depiction and scan time, while enabling free-breathing acquisition, whole-heart coverage, reformatting in arbitrary views and visualization of both water and fat information.
dc.format.extent14 páginas
dc.fuente.origenAutoarchivo
dc.identifier.citationJournal of Cardiovascular Magnetic Resonance. 2021 May 24;23(1):62
dc.identifier.doi10.1186/s12968-021-00751-2
dc.identifier.urihttps://doi.org/10.1186/s12968-021-00751-2
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/60462
dc.issue.numeroNo. 62
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final14
dc.pagina.inicio1
dc.revistaJournal of Cardiovascular Magnetic Resonancees_ES
dc.rightsacceso abierto
dc.rights.holderThe Author(s)
dc.subject3D whole-heartes_ES
dc.subjectRespiratory motion correctiones_ES
dc.subjectLate gadolinium enhancementes_ES
dc.subjectDixon water/fat separationes_ES
dc.subject.ddc616.07548
dc.subject.deweyMedicina y saludes_ES
dc.title3D whole-heart grey-blood late gadolinium enhancement cardiovascular magnetic resonance imaginges_ES
dc.typeartículo
dc.volumenVol. 23
sipa.codpersvinculados14195
sipa.codpersvinculados1015313
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
12968_2021_Article_751.pdf
Size:
1.98 MB
Format:
Adobe Portable Document Format
Description:
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
0 B
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Artículos de revistas