Cardiac dyssynchrony correlates with left ventricular remodeling after myocardial infarction

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dc.contributor.authorMcNab, Paul
dc.contributor.authorCastro, Pablo
dc.contributor.authorGabrielli, Luigi
dc.contributor.authorVerdejo, Hugo
dc.contributor.authorCarlos Quintana, Juan
dc.contributor.authorRodriguez, Jose A.
dc.contributor.authorCorbalan, Ramon
dc.date.accessioned2024-01-10T13:10:00Z
dc.date.available2024-01-10T13:10:00Z
dc.date.issued2009
dc.description.abstractBackground: Cardiac dyssynchrony is common in advanced heart failure (HF), but the changes in cardiac synchrony after myocardial infarction (MI) have not been adequately described. Aim: To study the relationship between cardiac synchrony and left ventricular remodeling after acute myocardial infarction. Material and methods: Forty nine patients aged 59+/-10 years (77% men) with a first episode of a ST segment elevation MI were studied. Scintigraphic left ventricular function and synchrony analyses were performed at baseline and after a six months follow-up. Determinations were compared with 33 healthy subjects. Results: At baseline, patients with MI had a decreased left ventricular ejection fraction (LVEF) and significant dyssynchrony, when compared with controls. LVEF was 36.4%+/-10%, left ventricular end-diastolic volume (LVEDV) 127+/-38 mL, interventricular delay (IEV) 29+/-35 milliseconds (ms), and intraventricular delay (IAV), 234+/-89 ms. After 6 months, LVEF significantly improved (38%+/-10%, p = 0.042) without significant changes in LVEDV (129+/-32 mL, p = 0.97), IEV (24+/-17, p = 0.96) or IAV (231 +/- 97, p = 0.34). At baseline there were significant correlations between IAV and LVEF, and between IAV and LVEDV (r = -0.48, p = 0.001 and r = -0.41, p = 0.004, respectively). These correlations remained significant after 6 months. There was a positive correlation between IAV and LVEDV changes at six months (r = 0.403, p = 0.04). Conclusions: The development of cardiac dyssynchrony correlates with adverse left ventricular remodeling after MI (Rev Med Chile 2009; 137: 1457-62).
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:20098804
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77741
dc.identifier.wosidWOS:000273061900007
dc.information.autorucFacultad de Medicina; Verdejo Pinochet, Hugo Eduardo; S/I; 1001175
dc.issue.numero11
dc.language.isoes
dc.nota.accesoSin adjunto
dc.pagina.final1462
dc.pagina.inicio1457
dc.publisherSOC MEDICA SANTIAGO
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsregistro bibliográfico
dc.subjectCardiac dyssynchrony
dc.subjectMyocardial infarction
dc.subjectVentricular remodeling
dc.subjectHEART-FAILURE PATIENTS
dc.subjectINTRAVENTRICULAR DYSSYNCHRONY
dc.subjectRESYNCHRONIZATION THERAPY
dc.subjectDILATED CARDIOMYOPATHY
dc.subjectCONTRACTION
dc.subjectMORTALITY
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCardiac dyssynchrony correlates with left ventricular remodeling after myocardial infarction
dc.typeartículo
dc.volumen137
sipa.codpersvinculados1001175
sipa.indexWOS
sipa.indexPubmed
sipa.trazabilidadCarga SIPA;09-01-2024
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