Publicaciones académicas

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Esta colección incluye artículos de profesores de la Pontificia Universidad Católica de Chile, publicados en revistas nacionales y extranjeras.

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1, 2, 3, 4, 5 . . . 43: Justice! Ay! Ay! Ayotzinapa: A Challenge for New Critical Qualitative Inquiry
(2016) Cisneros Puebla, Cesar A.; Alatorre, Francisco; Allen, Mitchell; Benard, Silvia; Castaneda, Dolores; Castaneda, Yvette; Charmaz, Kathy; Davidson, Judy; de la Garza, Sarah Amira; Espinoza, Adriana; Faulkner, Sandra L.; Ferreyra, Gabriel; Gilgun, Jane; Gutierrez, Luis Felipe Gonzalez; Hein, Serge F.; Hernandez, Doris; Biber, Sharlene Hesse; Labarthe, Vanessa Jara; Johnson, John M.; Keller, Reiner; Lather, Patti; Long, Tanya A.; Pourreau, Leslie; Rawlins, William K.; Rinehart, Robert E.; Donoso, Gabriela Rubilar; Ryen, Anne; Orozco, Miguel Angel Soto; Tamas, Sophie; Tilley-Lubbs, Gresilda A.
1,1′:4′,1′′-Terphenyl-2′,5′-dicarb-oxy- lic acid dimethyl sulfoxide-d6 disolvate
(2012) Pop, L.C.; Preite, Marcelo Daniel; Manríquez M., Juan Manuel; Vega, A.; Chávez Madariaga, Ivonne
1,2,3,4,5-PENTAMETHYLCYCLOPENTADIENE
(1982) Manríquez M., Juan Manuel; Fagan, Paul J.; Schertz, Larry D.; Marks, Tobin J.; Bercaw, John; Mcgrady, Nancy
1,4-Dihydropyridines: Reactivity of nitrosoaryl and nitroaryl derivatives with alkylperoxyl radicals and ABTS radical cation
(2004) Valenzuela, V.; Santander, P.; Camargo, C.; Squella, J.A.; López Alarcón, Camilo Ignacio; Nuñez Vergara, L.J.
1-[1-(4-Chlorobenzenesulfonyl)-1H-indole-3-yl]-3[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one
(2018) Diethelm Varela, Benjamín Manuel; Almendras Riesco, Sebastián Ignacio; Recabarren Gajardo, Gonzalo
1-benzoyl-2-(2-nitrophenyl)-1H-benzimidazole derivatives: A novel approach to the development of new HIV-1 reverse transcriptase inhibitors
(2007) Vásquez Velásquez, David; Lagos Arévalo, Carlos Fernando; Mella Raipán, Jaime Alberto; González Contreras, Luis Gerardo; Ebensperger González, Roberto Alejandro; Alvarez Figueroa, María Javiera; Sáez Moya, Edmundo Alfredo; Pessoa Mahana, Hernán; Araya Secchi, Raul; Gonzalez Wong, Angel; Perez-Acle, Tomas; Pessoa Mahana, Carlos David
1-D memristor-based cellular automaton for pseudo-random number generation
(IEEE, 2017) Karamani, Rafailia Eleni; Ntinas, Vasileios; Vourkas, Ioannis; Sirakoulis, Georgios C.
Cellular Automata (CAs) is a well-known parallel, bio-inspired, computational model. It is based on the capability of simpler, locally interacting units, i.e. the CAs cells, to evolve in time, giving rise to emergent computation, suitable to model physical system behavior, prediction of natural phenomena and multi-dimensional problem solutions. Moreover, at the same time CAs constitute a promising computing platform, beyond the von Neumann architecture. In this paper, a memristor device is considered to be the basic module of a CA cell circuit implementation, performing as a combined memory and processing element to implement CA-based circuits, able to model sufficiently systems and applications as mentioned above, targeting tentatively to a more energy efficient design compared to the conventional electronics. In particular and as a proof of concept, the results of elementary CAs modeling and simulation for the generation of pseudo-random numbers are presented using a 1-D memristor-based CAs array to illustrate the robustness and the efficacy of the proposed computing approach.
1-THz bandwidth of 70-krad/s endless optical polarization control
(2014) Koch, Benjamin; Noe, Reinhold; Mirvoda, Vitali; Sandel, David
10 Years of Digital Journalism (Studies): The Past, the Present, the Future
(ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD, 2023) Westlund, Oscar; Hess, Kristy; Saldana, Magdalena; Tandoc, Edson C.
The Digital Journalism editorial team is thrilled to introduce this 10th anniversary special issue. At the beginning of 2022, we invited our international editorial board to contribute to this important collection, which aims to explore the diverse and multi-disciplinary nature of digital journalism studies. We called for contributions that consider the "big picture" of the field and look at the past and the present of digital journalism studies. We also invited articles focusing on digital journalism studies for the future, considering trends, concepts, theories, methodologies, and key issues that will shape research in the decades ahead. This special issue features six articles, advancing systematic empirical assessments of developments in the field, as well as critical discussions around the developments and politics of digital journalism studies.
10-MV SBRT FFF irradiation technique is associated to the lowest peripheral dose: the outcome of 142 treatment plans for the 10 most common tumour locations
(2019) Irazola, Leticia; Sánchez Nieto, Beatriz; García Hernández, M. T.; Terrón, J. A.; Roselló, J.; Ortiz-Seidel, M.; Béjar, M. J.; Linares, Rafael; Velázquez, Santiago; Sánchez Doblado, Francisco
10-year experience in patients operated for acute invasive fungal rhinosinusitis
(2020) Lagos, A.; Ferrada, S.; Muñoz, T.; Maul Fonseca, Ximena; Finkelstein, A.; González, C.; Fonseca Arrieta, María Ximena; Callejas Canepa, Claudio Andrés
100 covers, 100 possibilities
(2018) Valenzuela M, Carolina
100% Efficient three-dimensional coronary MR angiography with two-dimensional beat-to-beat translational and bin-to-bin affine motion correction
(2015) Aitken, A.; Henningsson, M.; Botnar, René Michael; Schaeffter, T.; Prieto Vásquez, Claudia
1000 years of population, warfare, and climate change in pre-Columbian societies of the Central Andes
(2023) Lima, Mauricio; Gayo, Eugenia M.; Gurruchaga, Andone; Estay, Sergio A.; Santoro, Calogero M.
Different Andean societies underwent processes of expansion and collapse during propitious or adverse climate conditions, resource boost or depletion along with population variations. Previous studies have emphasized that demographic collapses of polities in the Central Andes Area were triggered by warfare and the negative impacts of fluctuating climate (droughts) on crop productivity. Nevertheless, the interactions between climatic variability, demography and warfare have been less thoroughly evaluated. We develop population dynamic models to test feedback relationships between population growth, climate change and warfare in the Central Andes, where considerable regional hydroclimate variations have occurred over a millennium. Through population models, we found out that the rise and demise of social polities in the northern coast of the Central Andes appear to be a consequence of climate change. In contrast, for the highlands of Peru and the Titicaca basin, population models suggest that warfare intensity has a negative effect on population growth rates.
100krad/s endless polarisation tracking with miniaturised module card
(2011) Koch, Benjamin; Noé, R.; Mirvoda, V.; Sandel, D.
10Be chronology of the Last Glacial Maximum and Termination in the Andes of central Chile: The record of the Universidad Glacier (34° S)
(Elsevier Ltd., 2024) Fernández Navarro, Hans Andrés; García B., Juan Luis; Nussbaumer, Samuel U.; Tikhomirov, Dmitry; Pérez Mora, Francia Débora; Gartner Roer, Isabelle; Christl, Marcus; Egli, Markus
Reconstructing mid-latitude glacier variations is a prerequisite for unveiling the interhemispheric climate linkages and atmospheric-ocean forcings that triggered those changes during the last glacial cycle. Nonetheless, the timing, magnitude, and structure of glacier fluctuations in the southern mid-latitudes remain incomplete. Here, we present a new Be-10 chronology of the Universidad Glacier in the Andes of central Chile (34 degrees S, 70 degrees W; similar to 2500 m a.s.l.) based on 21 cosmogenic-exposure ages of boulders on discrete moraine ridges defining former ice margins. Our findings include the mapping and dating of three moraines, UNI I, UNI II, and UNI III, located similar to 20 km, 15 km, and 10 km down-valley from the present-day glacier front, respectively. The Be-10 exposure ages of the UNI I moraine range from 135.9 +/- 7.1 to 51.4 +/- 2.7 ka (n = 3). The UNI II moraine gave a mean age of 18.0 +/- 0.9 (n = 15) and the UNI III moraine yielded a mean age of 13.9 +/- 0.8 ka (n = 3). The UNI I moraine implies the largest ice extent during a pre-Last Glacial Maximum (pre-LGM) period, including the penultimate glaciation. The UNI II is a moraine complex that represents cold and humid conditions in central Chile at the end of the LGM, which we attribute to the northward-shift of the Southern Westerly Winds (SWW). The UNI III moraine represents a return to glacial conditions interrupting the Termination, evidencing both a double-step deglacial trend observed through the southern middle and high latitudes at the end of the last ice age. The Andes at this subtropical latitude record a global signal of glacial and climate change.
11 beta-hydroxysteroid dehydrogenase activity in patients with hypertension and low plasma renin activity
(2002) Mosso, L; Carvajal, C; Campino, C; Rojas, A; Gonzalez, A; Barraza, A; Montero, J; Fardella, C; NCD Risk Factor Collaboration (NCD-RisC)
Background: Half of hypertensive patients with, low plasma renin activity have a primary hyperaldosteronism. Among the remaining half 11beta-hydroxysteroid dehydrogenase type 2 (11betaHSD2) deficiency plays all important role. This enzyme catalyzes the conversion of cortisol to cortisone, avoiding the interaction of cortisol with, the mineralocorticoid receptor. If the enzyme fails, cortisol will stimulate sodium and water reabsorption and increase blood pressure. Aim: To determine biochemical alterations, suggestive of 11betaSHSD2 deficiency, in low-renin hypertensive patients. Patients and Methods: Twenty eight hypertensive patients with a plasma renin activity of less than 0.5 ug/ml/h and with a plasma aldosterone of less than 5 ng/dl were studied. Twenty eight normotensive patients were studied as controls. Serum. cortisol (RIA), cortisone (ELISA) and the serum cortisol/cortisone ratio were determined in all of them, between, 9 and 10 AM. Measurements were confirmed by high pressure liquid chromatography. The serum cortisol/cortisone ratio was considered abnormal when its Ln (cortisol/cortisone) value was over 2 standard deviations of the mean. Results: Serum cortisol was higher in hypertensive subjects than in controls (11.1 +/- 3.3 and 9.2 +/- 2.8 mug/dl, respectively; p <0.05). No differences were observed in serum cortisone (3.4 +/- 1.3 and 3.7 +/- 1.2 μg/dl, respectively). Four hypertensive subjects bad all abnormally high Ln (cortisol/cortisone) value (1.86; 1.73; 2.07 and 2.01, considering a normal value of less than 1.61). Conclusions: Four of 28 hypertensive subjects with, low plasma renin activity and aldosterone had biochemical alterations suggestive of 11.1βHSD2 deficiency.
11 beta-Hydroxysteroid Dehydrogenase Type 1 is Overexpressed in Subcutaneous Adipose Tissue of Morbidly Obese Patients
(SPRINGER, 2009) Munoz, Rodrigo; Carvajal, Cristian; Escalona, Alex; Boza, Camilo; Perez, Gustavo; Ibanez, Luis; Fardella, Carlos
11 beta-Hydroxysteroid dehydrogenase type 1 (11 beta-HSD1) enzyme catalyzes interconversion of inactive cortisone to active cortisol. Its expression in adipose tissue has been associated with obesity and some of its metabolic disorders. Controversies regarding which fat depots [subcutaneous adipose tissue (SAT) or visceral adipose tissue (VAT)] have higher expression still remain. The aim of this work was to evaluate 11 beta-HSD1 expression in SAT and VAT of obese patients and evaluate its association to metabolic features of metabolic syndrome.
11 beta-hydroxysteroid dehydrogenase type-2 and type-1 (11 beta-HSD2 and 11 beta-HSD1) and 5 beta-reductase activities in the pathogenia of essential hypertension
(HUMANA PRESS INC, 2010) Campino, Carmen; Carvajal, Cristian A.; Cornejo, Javiera; San Martin, Betty; Olivieri, Oliviero; Guidi, Giancesare; Faccini, Giovanni; Pasini, Francesco; Sateler, Javiera; Baudrand, Rene; Mosso, Lorena; Owen, Gareth I.; Kalergis, Alexis M.; Padilla, Oslando; Fardella, Carlos E.
Cortisol availability is modulated by several enzymes: 11 beta-HSD2, which transforms cortisol (F) to cortisone (E) and 11 beta-HSD1 which predominantly converts inactive E to active F. Additionally, the A-ring reductases (5 alpha- and 5 beta-reductase) inactivate cortisol (together with 3 alpha-HSD) to tetrahydrometabolites: 5 alpha THF, 5 beta THF, and THE. The aim was to assess 11 beta-HSD2, 11 beta-HSD1, and 5 beta-reductase activity in hypertensive patients. Free urinary F, E, THF, and THE were measured by HPLC-MS/MS in 102 essential hypertensive patients and 18 normotensive controls. 11 beta-HSD2 enzyme activity was estimated by the F/E ratio, the activity of 11 beta-HSD1 in compare to 11 beta-HSD2 was inferred by the (5 alpha THF + 5 beta THF)/THE ratio and 5 beta-reductase activity assessed using the E/THE ratio. Activity was considered altered when respective ratios exceeded the maximum value observed in the normotensive controls. A 15.7% of patients presented high F/E ratio suggesting a deficit of 11 beta-HSD2 activity. Of the remaining 86 hypertensive patients, two possessed high (5 alpha THF + 5 beta THF)/THE ratios and 12.8% had high E/THE ratios. We observed a high percentage of alterations in cortisol metabolism at pre-receptor level in hypertensive patients, previously misclassified as essential. 11 beta-HSD2 and 5 beta-reductase decreased activity and imbalance of 11 beta-HSDs should be considered in the future management of hypertensive patients.
112Gb/s PolMux RZ-DQPSK with fast polarization tracking based on interference control
(2009) Wernz, H.; Bayer, S.; Olsson, B.E.; Camera, M.; Griesser, H.; Furst, C.; Koch, Benjamin; Mirvoda, V.; Hidayat, A.; Noe, R.

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