Browsing by Author "Speisky, Hernán"
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- ItemA Polyvinylpolypyrrolidone (PVPP)-Assisted Folin-Ciocalteu Assay to Assess Total Phenol Content of Commercial Beverages(2014) Bridi, Raquel; Troncoso, M.; Folch Cano, C.; Fuentes, J.; Speisky, Hernán; López Alarcón, Camilo Ignacio
- ItemAnalytical Parameters of the Microplate-Based ORAC-Pyrogallol Red Assay(2011) Ortiz, Rocio; Antilén Lizana, Mónica; Speisky, Hernán; Aliaga Miranda, Margarita Elly; López Alarcón, Camilo Ignacio
- ItemAntioxidant capacity of phenolic compounds in acidic medium : a pyrogallol red-based ORAC (oxygen radical absorbance capacity) assay(2013) Atala, Elias; Aspee, Alexis; Speisky, Hernán; Lissi, Eduardo; López Alarcón, Camilo Ignacio
- ItemAntioxidant effect of 5-amino salicylic acid on copper-mediated LDL oxidation(2007) López Alarcón, Camilo Ignacio; Speisky, Hernán; Lissi, Eduardo
- ItemAntioxidant screening of medicinal herbal teas(2006) Speisky, Hernán; Rocco, C.; Carrasco, C.; Lissi, E.A.; López Alarcón, Camilo Ignacio
- ItemApplication of a Microplate-Based ORAC-Pyrogallol Red Assay for the Estimation of Antioxidant Capacity: First Action 2012.03(2012) Ortiz, Rocio; Antilén Lizana, Mónica; Speisky, Hernán; Aliaga Miranda, Margarita Elly; López Alarcón, Camilo Ignacio; Baugh, Steve
- ItemAssessment of the redox cycling properties of nitrocompounds using a superoxide-dependent pyrogallol red bleaching assay(2012) López Alarcón, Camilo Ignacio; Speisky, Hernán; Aliaga Miranda, Margarita Elly; Lissi, E.; Rojas, M.; Faúndez Cáceres, Mario
- ItemContent of flavonoids and phenolic compounds in Chilean honeys. Orac index.(2007) Munoz, O; Copaja, S; Speisky, Hernán; Pena, RC; Montenegro Rizzardini, Gloria
- ItemCu(I)-glutathione complex: A potential source of superoxide radicals generation(2008) Speisky, Hernán; Gomez, Maritza; Carrasco-Pozo, Catalina; Pastene, Edgar; López Alarcón, Camilo Ignacio; Olea-Azar, Claudio
- ItemCu(II)-disulfide complexes display simultaneous superoxide dismutase- and catalase-like activities(2013) Aliaga Miranda, Margarita Elly; Andrade Acuña, Daniela; López Alarcón, Camilo Ignacio; Sandoval Acuña, Cristián; Speisky, Hernán
- ItemDouble edge redox-implications for the interaction between endogenous thiols and copper ions: In vitro studies(2008) Carrasco-Pozo, Catalina; Aliaga Miranda, Margarita Elly; Olea-Azar, Claudio; Speisky, Hernán
- ItemFirst Web-Based Database on Total Phenolics and Oxygen Radical Absorbance Capacity (ORAC) of Fruits Produced and Consumed within the South Andes Region of South America(2012) Speisky, Hernán; López Alarcón, Camilo Ignacio; Gomez, Maritza; Fuentes, Jocelyn; Sandoval-Acuna, Cristian
- ItemGeneration of superoxide radicals by copper-glutathione complexes: Redox-consequences associated with their interaction with reduced glutathione(2009) Speisky, Hernán; Gomez, Maritza; Burgos-Bravo, Francesca; López Alarcón, Camilo Ignacio; Jullian, Carolina; Olea-Azar, Claudio; Aliaga Miranda, Margarita Elly
- ItemImpact of pomegranate peel extract on gut microbiota composition and metabolic health parameters in high-fat diet-fed mice(2024) Duarte, Lissette; Bustamante, Andrés; Orellana, Juan Francisco; Valenzuela, Rodrigo; Magne, Fabien; Fuentes, Jocelyn; Speisky, Hernán; Echeverria Gonzalez, Francisca CeciliaBackground: Gut microbiota (GM) plays a crucial role in obesity pathophysiology and is heavily influenced by dietary factors. Polyphenols have shown a positive effect in preventing and treating obesity, which is blunted in the absence of GM. Pomegranate peel, known for its high content of polyphenols (ellagitannins), has been found to exhibit favorable metabolic effects in obesity. Interestingly, ellagitannins are metabolized by the action of GM. However, the specific impact of pomegranate peel extract (PPE) on GM and metabolism remains unclear.Objective: to evaluate the effect of a PPE (microencapsulated or not) on the composition of GM in high-fat diet (HFD)-fed mice and analyze its association with metabolic parameters.Methods: Male C57BL/6J mice (n = 40) were randomly distributed into five groups: control diet (CD), HFD, HFD + inulin (IN), HFD + PPE (50 mg/kg/d of total polyphenols; TP), and HFD + MPPE (50 mg/kg/d TP), for 14 weeks. Liver and serum antioxidant status were assessed. GM composition, further relative abundances, and biodiversity were calculated from cecal content samples. The bacterial community clustering was analyzed using a canonical-correlation analysis (CCA). GM parameters and metabolic outcomes were evaluated for correlation (Spearman’s correlation), p < 0.05.Results: PPE and MPPE showed increased energy expenditure, reduced liver arachidonic acid content, elevated antioxidant capacity, and higher GM alpha diversity compared to HFD alone.Conclusion: PPE, regardless of encapsulation, ameliorated metabolic alterations induced by HFD, potentially through modulation of GM. These findings provide data on the therapeutic potential of PPE in managing obesityrelated metabolic dysfunction.
- ItemIn vitro interaction between homocysteine and copper ions: Potential redox implications(2006) Carrasco-Pozo, Catalina; Alvarez-Lueje, Alejandro; Olea-Azar, Claudio; López Alarcón, Camilo Ignacio; Speisky, Hernán
- ItemInhibition of mitochondrial complex I by various non-steroidal anti-inflammatory drugs and its protection by quercetin via a coenzyme Q-like action(2012) Sandoval-Acuna, Cristian; López Alarcón, Camilo Ignacio; Aliaga Miranda, Margarita Elly; Speisky, Hernán
- ItemInteraction of 5-aminosalicylic acid with nitrous acid: formation of the diazonium derivative and nitric oxide release(2011) López Alarcón, Camilo Ignacio; Lissi, Eduardo; Hoffmann, Pascal; Mella Raipán, Jaime Alberto; Pessoa Mahana, Carlos David; Speisky, Hernán; Moller, Matias; Ferrer-Sueta, Gerardo; Denicola, Ana
- ItemInternational Regulations of Propolis Quality : Required Assays do not Necessarily Reflect their Polyphenolic‐Related In Vitro Activities(2015) Bridi, Raquel; Montenegro Rizzardini, Gloria; Nunez-Quijada, G.; Giordano Villatoro, Ady; Moran-Romero, M.F.; Jara-Pezoa, I.; Speisky, Hernán; Atala, E.; López Alarcón, Camilo Ignacio
- ItemMechanism of Pyrogallol Red Oxidation Induced by Free Radicals and Reactive Oxidant Species. A Kinetic and Spectroelectrochemistry Study(2013) Atala, E.; Velasquez, G.; Vergara, C.; Mardones, C.; Reyes, J.; Tapia Apati, Ricardo; Quina, F.; Mendes, M.; Speisky, Hernán; Lissi, E.; Ureta Zañartu, M.; Aspee, A.; López Alarcón, Camilo Ignacio
- ItemOxidation of free, peptide and protein tryptophan residues mediated by AAPH-derived free radicals: role of alkoxyl and peroxyl radicals(2016) Fuentes Lemus, Eduardo Felipe; Dorta Pérez, Eva; Escobar Álvarez, Elizabeth; Aspée, A.; Pino, E.; Abasq, M. L.; Speisky, Hernán; Silva, E.; Lissi, E.; Davies, M. J.; López Alarcón, Camilo Ignacio