Browsing by Author "Romero Parra, Javier Hernán"
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- ItemA combined CoMFA and CoMSIA 3D-QSAR study of benzamide type antibacterial inhibitors of the FtsZ protein in drug-resistant Staphylococcus aureus(2015) Andrades, J.; Campanini, J.; Vasquez, D.; Silvestri, C.; Morales, C.; Romero Parra, Javier Hernán; Mella, J.
- ItemDesign, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles—A New Family of High Affinity CB1 Cannabinoid Ligands(2013) Espinosa Bustos, Christian; Iturriaga Vásquez, Patricio; Lagos, Carlos; Mella Raipán, Jaime; Pessoa Mahana, Carlos David; Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo Iván; Romero Parra, Javier HernánA series of novel 2-pyridylbenzimidazole derivatives was rationally designed and synthesized based on our previous studies on benzimidazole 14, a CB1 agonist used as a template for optimization. In the present series, 21 compounds displayed high affinitie
- ItemDesign, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1(2015) Espinosa Bustos, Christian Marcelo; Lagos, Carlos F.; Romero Parra, Javier Hernán; Zárate Méndez, Ana María; Mella Raipán, Jaime Alberto; Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo; Iturriaga Vásquez, Patricio; Tapia Apati, Ricardo; Pessoa Mahana, Carlos David
- ItemSynthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor(2016) Romero Parra, Javier Hernán; Mella Raipán, Jaime Alberto; Palmieri, Vittoria; Allarà, Marco; Torres Torres, María José; Pessoa Mahana, Hernán; Iturriaga Vásquez, Patricio; Escobar, Rossy; Faundez, Mario; Di Marzo, Vicenzo; Pessoa Mahana, Carlos David
- ItemSynthesis, characterization, and electrochemical studies of new 5- and 6-nitro N-acyl-1H-indazoles(2011) Recabarren Gajardo, Gonzalo; Gacitúa Santelices, Manuel Alejandro; Murueva, I.; Romero Parra, Javier Hernán; Espinosa Bustos, Christian Marcelo; Mella Raipán, Jaime Alberto; Valle de la Cortina, María Angélica del; Pessoa Mahana, Carlos David; Tapia, Raymundo