Browsing by Author "Pessoa Mahana, Hernán"
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- Item1-benzoyl-2-(2-nitrophenyl)-1H-benzimidazole derivatives: A novel approach to the development of new HIV-1 reverse transcriptase inhibitors(2007) Vásquez Velásquez, David; Lagos Arévalo, Carlos Fernando; Mella Raipán, Jaime Alberto; González Contreras, Luis Gerardo; Ebensperger González, Roberto Alejandro; Alvarez Figueroa, María Javiera; Sáez Moya, Edmundo Alfredo; Pessoa Mahana, Hernán; Araya Secchi, Raul; Gonzalez Wong, Angel; Perez-Acle, Tomas; Pessoa Mahana, Carlos David
- ItemA facile approach for new dibenzo [b,f][1,5] diazocinones(2005) Pessoa Mahana, Hernán; Martínez Aránguiz, Karen G.; Araya Maturana, Ramiro; Pessoa Mahana, Carlos David
- ItemA Synthetic Overview of New Molecules with 5-HT1A Binding Affinities(2003) Pessoa Mahana, Hernán; Araya Maturana, Ramiro; Saitz Barría, Claudio Antonio; Pessoa Mahana, Carlos David
- ItemAccess to quinazolines from 2-nitrobenzaldehyde and arylamines(1999) Valderrama Guerrero, Jaime Adolfo; Pessoa Mahana, Hernán; Sarras, G.; Tapia Apati, Ricardo
- ItemBiological evaluation of novel 6-arylbenzimidazo [1,2-c]quinazoline derivatives as inhibitors of LPS-induced TNF-alpha secretion(2008) Galarce, Gloria D.; Foncea Ávila, Rocío Eugenia; EdwardsM., Ana M; Pessoa Mahana, Hernán; Pessoa Mahana, Carlos David; Ebensperger González, Roberto Alejandro
- ItemDesign, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles—A New Family of High Affinity CB1 Cannabinoid Ligands(2013) Espinosa Bustos, Christian; Iturriaga Vásquez, Patricio; Lagos, Carlos; Mella Raipán, Jaime; Pessoa Mahana, Carlos David; Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo Iván; Romero Parra, Javier HernánA series of novel 2-pyridylbenzimidazole derivatives was rationally designed and synthesized based on our previous studies on benzimidazole 14, a CB1 agonist used as a template for optimization. In the present series, 21 compounds displayed high affinitie
- ItemDesign, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1(2015) Espinosa Bustos, Christian Marcelo; Lagos, Carlos F.; Romero Parra, Javier Hernán; Zárate Méndez, Ana María; Mella Raipán, Jaime Alberto; Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo; Iturriaga Vásquez, Patricio; Tapia Apati, Ricardo; Pessoa Mahana, Carlos David
- ItemErratum: Synthesis of 1-benzyl-3-[4-(aryl-1-piperazinyl) carbonyl]-1h-indoles. Novel ligands with potential d4 dopaminergic activity (Journal of the Chilean Chemical Society (2012) 56:4 (866-869))(2012) Pessoa Mahana, Hernán; Ignacio, C.M.; Pessoa Mahana, Carlos David; Araya Maturana, Ramiro; Almodovar, Iriux; Saitz Barría, Claudio Antonio
- ItemFURAN RING-OPENING REACTIONS OF 5-HYDROXY-2,3-DIHYDROBENZO[B]FURANS(1993) Valderrama Guerrero, Jaime Adolfo; Gonzalez, M.F.; Arias, P.; Pessoa Mahana, Hernán; Tapia Apati, Ricardo
- ItemSolvent-free microwave-promoted Michael addition of aza-nucleophiles to benzo[b] thiophen-2-yl-2-propenone(2009) Pessoa Mahana, Hernán; González, Marcos; González Cisterna, Pablo Marcelo; Pessoa Mahana, Carlos David; Araya Maturana, Ramiro; Ron Higuera, Nadia Betsabé; Saitz Barría, Claudio Antonio
- ItemSolvent-free synthesis of 6-arylbenzimidazo[1,2-c]quinazolines under microwave irradiation(2004) Pessoa Mahana, Hernán; Pessoa Mahana, Carlos David; Salazar, Ricardo; Valderrama Guerrero, Jaime Adolfo; Saez, Edmundo; Araya Maturana, Ramiro
- ItemSTUDIES ON QUINONES .25. SYNTHETIC APPROACHES TO 6,9-DIOXYGENATED-BENZAZEPINONES(1993) Valderrama Guerrero, Jaime Adolfo; Pessoa Mahana, Hernán; Tapia Apati, Ricardo
- ItemStudies on Quinones. Part 22.' Synthesis of 1-Benzazepine-6,9-Quinone Derivatives(1992) Valderrama Guerrero, Jaime Adolfo; Pessoa Mahana, Hernán; Tapia Apati, Ricardo
- ItemStudies on quinones. Part 23. Synthesis of azepinones fused to quinone systems(1992) Valderrama Guerrero, Jaime Adolfo; Pessoa Mahana, Hernán; Tapia Apati, Ricardo
- ItemStudies on quinones. Part 36. Synthesis and trypanocidal activity of 2-alkoxycarbonylbenzo[b]thiophene-4,7-quinones(2002) Pessoa Mahana, Carlos David; Valderrama Guerrero, Jaime Adolfo; Olmos, María G.; Espinoza, Omar A.; Pessoa Mahana, Hernán; Rojas de Arias, Antonieta; Nakayama, Héctor David; Torres de Ortíz, Susana; Miret, Jorge
- ItemSynthesis and biological evaluation of potential acetylcholinesterase inhibitors based on a benzoxazine core(2018) Mendez Rojas, C.; Quiroz, G.; Faúndez Cáceres, Mario; Gallardo Garrido, C.; Pessoa Mahana, Carlos David; Chung, H.; Gallardo Toledo, E.; Saitz Barría, Claudio Antonio; Araya Maturana, Ramiro; Kogan, M.; Muniga Lopez, M.; Iturriaga Vasquez, P.; Valenzuela Gutierrez, C.; Pessoa Mahana, Hernán
- ItemSynthesis and docking of novel 3-indolylpropyl derivatives as new polypharmacological agents displaying affinity for 5-HT1AR/SERT(2016) Pessoa Mahana, Hernán; Silva Matus, Paul; Pessoa Mahana, Carlos David; Chung, Hery; Iturriaga Vásquez, Patricio; Quiroz, Gabriel; Möller Acuña, Patricia; Zapata Torres, Gerald; Saitz Barría, Claudio Antonio; Araya Maturana, Ramiro; Reyes Parada, Miguel
- ItemSynthesis of 1-benzyl-3-[4-(aryl-1-piperazinyl) carbonyl]-1h-indoles. novel ligands with potential D4 dopaminergic activity(2011) Pessoa Mahana, Hernán; Cuevas, Ignacio M.; Pessoa Mahana, Carlos David; Araya Maturana, Ramiro; Fajardo, Iriux Almodovar; Barria, Claudio Saitz
- ItemSynthesis of 2-benzothienyl carbonyl 4-arylpiperazines as novel delavirdine analogs(2007) Pessoa Mahana, Hernán; Acevedo, R. Rodrigo; Saitz Barría, Claudio Antonio; Araya Maturana, Ramiro; Pessoa Mahana, Carlos David
- ItemSynthesis of 4-arylpiperazine derivatives of moclobemide: Potential antidepressants with a dual mode of action(2004) Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo; Araya Maturana, Ramiro; Kosche Cárcamo, Johann Albert; Pessoa Mahana, Carlos David