Browsing by Author "Padilla, O."

Now showing 1 - 7 of 7
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    Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis
    (2015) Pizarro, M.; Solís, Nancy; Quintero, P.; Barrera Martínez, Francisco José; Cabrera, D.; Rojas-de Santiago, P.; Arab Verdugo, Juan Pablo; Padilla, O.; Roa Strauch, Juan Carlos Enrique; Moshage, H.; Wree, A.; Inzaugarat, E.; Feldstein, A.; Fardella B., Carlos; Baudrand Biggs, René; Riquelme, A.; Arrese Jiménez, Marco
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    Gestational Hypothyroidism Improves the Ability of the Female Offspring to Clear Streptococcus pneumoniae Infection and to Recover From Pneumococcal Pneumonia
    (2016) Nieto Pacheco, Pamela Andrea; Penaloza, H.; Salazar, F.; Castellanos, R.; Opazo, M.; Venegas, L.; Padilla, O.; Kalergis Parra, Alexis Mikes; Riedel, C.; Bueno Ramírez, Susan
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    Impact of cognitive impairment, depression, disease activity, and disease damage on quality of life in women with systemic lupus erythematosus
    (2017) Calderón, J.; Flores, P.; Aguirre, J.; Valdivia Cabrera, Gonzalo; Padilla, O.; Barra, I.; Iscoriels, L.; Herrera, S.; González Arellano, Alejandro; Massardo Vega, Loreto
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    Methacholine challenge test by wheezing and oxygen saturation in preschool children with asthma
    (2015) Caussade Larraín, Marie Solange; Castro Rodríguez, José Antonio; Contreras, S.; Bugueño, R.; Ramírez, R.; Padilla, O.; Einisman, H.; Holmgren, N.; Caussade Larraín, Marie Solange; Castro Rodríguez, José Antonio; Contreras, S.; Bugueño, R.; Ramírez, R.; Padilla, O.; Einisman, H.; Holmgren, N.
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    Prevalence of emotional symptoms in Chilean oncology patients before the start of chemotherapy: Potential of the distress thermometer as an ultra-brief screening instrument
    (2014) Calderón, J.; Campla, C.; D'Aguzan, N.; Barraza, S.; Padilla, O.; Sánchez, C.; Palma, S.; González, M.
    Emotional distress (ED) is greater for oncology patients in comparison with the general population, and this has implications for the quality of life of the patient and his/her family, adherence to the treatment, and eventually, survivorship. In general, the detection of these symptoms is low, which explains the need for detection systems appropriate to the clinical reality of the oncology team. The objective of this study is to evaluate for the first time the usefulness of an ultra-brief screening instrument [distress thermometer (DT)], in a group of Chilean oncology patients. A total of 166 outpatients were evaluated at the Cancer Center of the Pontificia Universidad Católica de Chile, before starting chemotherapy. Two screening instruments were applied: Hospital Anxiety and Depression Scale (HADS) and DT. The application of HADS resulted in a prevalence of 32.7% of anxiety symptoms (HADS-A ≥ 8), 15.7% of depression symptoms (HADS-D ≥ 8), and 39.8% had a total score of HADS-T ≥ 11. The DT resulted in the prevalence of 32.5% of distress or ED (DT ≥ 5). The validity of the DT was evaluated as a screening tool in comparison with HADS, observing, in relation to the anxiety scale (HADS-A), a sensitivity of 88.9% and specificity of 78.4% (DT ≥ 4); depression (HADS-D), a sensitivity of 69.2% and specificity of 74.3% (DT ≥ 5); and in relation to the total scale (HADS-T), a sensitivity of 68.2% and specificity of 73.0% (DT ≥ 4). This study demonstrates the elevated prevalence of emotional symptoms in Chilean oncology patients, before the start of chemotherapy, and confirms the potential of the DT as a brief screening instrument with easy application. The DT will allow the clinician to increase the detection threshold in the Chilean oncology population, intervene in a timely manner, and contribute to the comprehensive handling of the oncology patient without affecting the time needed for assistance.
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    Quality of life in women with cervical cancer
    (2014) Urrutia, M. T.; Concha, X.; Padilla, O.
    Background: Quality of life (QOL) in women with cervical cancer can be affected by different reasons, because those women face not only changes in the physical and sexual domains, but also in social and psychosocial. Aim: To describe the QOL of a group of women with cervical cancer (CC) and to relate its different dimensions to the treatment and stage of cancer. Method: Analytical study was conducted on a group of 127 women with CC. Results: The age of women negatively correlated with the physical dimension. The type of treatment correlated negatively the physical, role and social domain, and it correlated positively with the fatigue symptom. The FIGO stage does not correlate in the univariate analysis. The type of treatment, with or without age interaction, predicts the physical, role, emotional domain and some symptoms such as insomnia and diarrhea in the multivariate analysis. Conclusion: QOL assessments during the course of CC disease are useful to projecting health outcomes to medium and long term and it should be incorporated as a routinely and standardized evaluation in order to make appropriate interventions.
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    Simulated training program in abdominal paracentesis for undergraduate medical students,Programa de entrenamiento simulado en paracentesis abdominal para estudiantes de medicina de pregrado
    (2019) Tejos, R.; Chahuán, J.; Uslar, T.; Inzunza, M.; Villagrán, I.; Riquelme, V.; Padilla, O.; Pizarro, M.; Corvetto, M.; Varas, J.; Riquelme, A.
    Background and aims: Abdominal paracentesis is an area that every general physician should know about, and the current learning model is unsafe for patients. Simulation allows students to develop their skills prior to clinical confrontation with minimal risks. The aims of this study were to design and evaluate a paracentesis simulation workshop for undergraduate students.