Browsing by Author "Iturriaga Vásquez, Patricio"
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- ItemDesign, Synthesis, Binding and Docking-Based 3D-QSAR Studies of 2-Pyridylbenzimidazoles—A New Family of High Affinity CB1 Cannabinoid Ligands(2013) Espinosa Bustos, Christian; Iturriaga Vásquez, Patricio; Lagos, Carlos; Mella Raipán, Jaime; Pessoa Mahana, Carlos David; Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo Iván; Romero Parra, Javier HernánA series of novel 2-pyridylbenzimidazole derivatives was rationally designed and synthesized based on our previous studies on benzimidazole 14, a CB1 agonist used as a template for optimization. In the present series, 21 compounds displayed high affinitie
- ItemDesign, synthesis, biological evaluation and binding mode modeling of benzimidazole derivatives targeting the cannabinoid receptor type 1(2015) Espinosa Bustos, Christian Marcelo; Lagos, Carlos F.; Romero Parra, Javier Hernán; Zárate Méndez, Ana María; Mella Raipán, Jaime Alberto; Pessoa Mahana, Hernán; Recabarren Gajardo, Gonzalo; Iturriaga Vásquez, Patricio; Tapia Apati, Ricardo; Pessoa Mahana, Carlos David
- ItemExperimental and theoretical study on the oxidation mechanism of dopamine in n-octyl pyridinium based ionic liquids-carbon paste modified electrodes(2013) Díaz Navarro, Carlos Patricio; García, Camilo; Iturriaga Vásquez, Patricio; Aguirre, María Jesús; Muena, Juan; Contreras, Renato; Ormazabal Toledo, Rodrigo; Isaacs Casanova, Mauricio
- ItemSynthesis and docking of novel 3-indolylpropyl derivatives as new polypharmacological agents displaying affinity for 5-HT1AR/SERT(2016) Pessoa Mahana, Hernán; Silva Matus, Paul; Pessoa Mahana, Carlos David; Chung, Hery; Iturriaga Vásquez, Patricio; Quiroz, Gabriel; Möller Acuña, Patricia; Zapata Torres, Gerald; Saitz Barría, Claudio Antonio; Araya Maturana, Ramiro; Reyes Parada, Miguel
- ItemSynthesis, 5-Hydroxytryptamine(1A) Receptor Affinity and Docking Studies of 3-[3-(4-Aryl-1-piperazinyl)-propyl]-1H-Indole Derivatives(2012) Pessoa Mahana, Hernán; Ugarte Núñez, Catalina; Araya Maturana, Ramiro; Saitz Barría, Claudio Antonio; Zapata Torres, Gerald; Pessoa Mahana, Carlos David; Iturriaga Vásquez, Patricio; Mella Raipán, Jaime Alberto; Reyes Parada, Miguel; Celis Barros, Cristian
- ItemSynthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor(2016) Romero Parra, Javier Hernán; Mella Raipán, Jaime Alberto; Palmieri, Vittoria; Allarà, Marco; Torres Torres, María José; Pessoa Mahana, Hernán; Iturriaga Vásquez, Patricio; Escobar, Rossy; Faundez, Mario; Di Marzo, Vicenzo; Pessoa Mahana, Carlos David