Browsing by Author "Echevarría, Ghislaine C."

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    Bloqueio perioperatório do plexo lombar e isquemia cardíaca em pacientes com fratura de quadril: ensaio clínico randomizado
    (2018) Altermatt, Fernando; Echevarría, Ghislaine C.; Cuadra F., Juan Carlos de la; Baeza Vergara, Ricardo Gabriel; Ferrada, Marcela; De La Cuadra Fontaine, Juan Carlos; Corvetto Aqueveque, Marcia Antonia
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    Chitotriosidase is a Biomarker for the Resistance to World Trade Center Lung Injury in New York City Firefighters
    (2013) Cho, Soo Jung; Nolan, Anna; Echevarría, Ghislaine C.; Kwon, Sonia; Naveed, Bushra; Schenck, Schenck; Tsukiji, Jun; Prezant, David J, Rom, William N, Weiden, Michael D.
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    Desarrollo y validación prospectiva de un sistema TCI a sitio efecto para propofol en niños
    (2008) León Muñoz, Paula; Fuentes Henríquez, Ricardo Sergio; Echevarría, Ghislaine C.; Cortínez Fernández, Luis Ignacio
    INTRODUCCIÓN: Aunque puede ofrecer ventajas respecto a las formas tradicionales de administración de propofol, no hay un sistema de TCI a sitio efecto de esta droga en niños. OBJETIVO: Desarrollar este sistema y evaluarlo prospectivamente. MATERIAL Y MÉTODO: Luego la aprobación por el Comité de Ética y de obtener consentimiento informado, se estudiaron niños entre 3 y 11 años, sometidos a cirugía con anestesia general, ASA I y sin premedicación. Además de la monitorización habitual en todos se colocó un monitor A2000 BIS® XP, version 3.2 con electrodos pediátricos BIS™ Sensor. El registro del monitor fue descargado a un computador para análisis externo de la información. El estudio se efectuó en 2 fases consecutivas. Fase 1 (n=25), luego de obtener una señal de BIS estable y preoxigenar, se administró un bolo de propofol de 3 mg x kg-1. Esto produjo una caída y recuperación del BIS que permitió la detección del tiempo de efecto máximo (tpeak). Fase 2 (n=40), el sistema TCI consistió en una bomba jeringa Fresenius Pilot 2 con una velocidad máxima de 1500 ml x hr-1 controlada por un computador cargado con el software Anestfusor® Serie II Pro. Usando el tpeak medido en la Fase 1 y el algoritmo de Minto1, la concentración en sitio efecto (Ce) de propofol fue inicialmente fijada en 5 µg x ml-1; cuando el sistema TCI había administrado el propofol necesario para alcanzar esta Ce y la bomba estaba detenida, se cambió la Ce a 4 µg x ml-1 que se mantuvo por 3 minutos hasta el final del estudio. Así, se obtuvo una Ce peak de 5 µg x ml-1 y luego un período estable en 4 µg x ml-1. Los 40 pacientes fueron randomizados para utilizar el modelo farmacocinético (PK) de Kataria2 o del Paedfusor3. Se midió el tiempo desde el inicio de la infusión hasta que se produjo la Ce peak (tpeak Ce) y hasta que se produjo el mínimo BIS (tpeak BIS). Además se midió el tiempo desde el fin de la infusión hasta que la Ce alcanzó 4 µg x ml-1 (tCe SS) y hasta que el BIS estuvo estable (tBIS SS). La performance del sistema TCI en condiciones dinámicas fue medida por la diferencia entre tpeak Ce y tpeak BIS (terror) y por el Error de Predicción (PE, %) (100*(tpeak BIS - tpeak Ce)/tpeak Ce). De estos valores se utilizó la mediana (MD terror y MDPE, respectivamente) y la mediana del valor absoluto (MDA terror y MDAPE, respectivamente), como índices de performance4. En el caso de la condición de pseudo equilibrio (SS), se calcularon similares índices con tCe SS y tBIS SS. Estadísticas: En la Fase 1 y 2 se utilizó estadísticas descriptivas. En la Fase 2 además los datos paramétricos fueron analizadon con test de Student no pareado y los no paramétricos con test de MannWhitney. Una p <0,05 fue considerada significativa. Los datos son media ± DE o mediana (rango). RESULTADOS: Fase 1: la edad de los pacientes fue de 6,5 (4-11) años y el tpeak de 65±14 s (n=25). Fase 2: la edad en el grupo Kataria fue 6,6 (4-11) años y en el Paedfusor 6,8 (4-11) años (NS). Parámetros de performance en Tabla. CONCLUSIONES: Durante la inducción, el sistema TCI se comporta dentro de lo clínicamente aceptable con ambos modelos PK. Sin embargo, durante la fase de mantención, mientras el modelo del Paedfusor se comporta dentro de rangos aceptables, el de Kataria no. Esto sugiere que el sistema TCI desarrollado para propofol en niños debiera ser usado a sitio efecto con el modelo PK del Paedfusor.
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    Early Elevation of Serum MMP-3 and MMP-12 Predicts Protection from World Trade Center-Lung Injury in New York City Firefighters : A Nested Case-Control Study
    (2013) Kwon, Sophia; Weiden, Michael D.; Echevarría, Ghislaine C.; Comfort, Ashley L.; Naveed, Bushra; Prezant, David J.; Rom, William N.; Nolan, Anna
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    Effect of acute arterial hypertension on morphine requirements and postsurgical pain
    (2015) Delfino, Alejandro; De La Fuente, Natalia; Altermatt, Fernando; Cortínez Fernández, Luis Ignacio; Echevarría, Ghislaine C.; Delfino, Alejandro; De La Fuente, Natalia; Altermatt, Fernando; Cortínez Fernández, Luis Ignacio; Echevarria, Ghislaine C.
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    Effect of Intrathecal fentanyl on secondary hyperalgesia, in patients undergoing anterior cruciate ligament repair
    (2020) Cuadra F., Juan Carlos de la; Echevarría, Ghislaine C.; Jara, X. P.; Fuente López, Natalia Francisca de la; Puga, V. A.; Miranda Hiriart, Pablo
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    Effect of intravenous fluid therapy on postoperative vomiting in children undergoing tonsillectomy
    (2013) Elgueta Le-Beuffe, María Francisca; Echevarría, Ghislaine C.; De La Fuente, Natalia; Cabrera, F.; Valderrama, A.; Cabezón, R.; Muñoz Letelier, Hernán Rodrigo; Cortínez Fernández, Luis Ignacio
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    Enlarged pulmonary artery is predicted by vascular injury biomarkers and is associated with WTC-Lung Injury in exposed fire fighters : a case control study
    (2014) Schenck, E.; Echevarría, Ghislaine C.; Girvin, F.; Kwon, S.; Comfort, A.; Rom, W.; Prezant, D.; Weiden, M.; Nolan, A.
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    Influencia de la obesidad en la farmacocinética de desflurano versus sevoflurano espirado
    (2008) Echevarría, Ghislaine C.; Cortinez, I.; Fuentes Henríquez, Ricardo Sergio; Muñoz Letelier, Hernán Rodrigo
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    Influencia de la posición en la visualización con ultrasonido del nervio ciático en la fosa poplítea por médicos en formación
    (2020) Miranda Hiriart, Pablo; Elgueta Le-Beuffe, María Francisca; Echevarría, Ghislaine C.; Bravo Bertoglio, María Pía; Cuadra F., Juan Carlos de la
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    Interventional procedures in children and adolescents with chronic non-cancer pain as part of a multidisciplinary pain treatment program
    (2018) Vega P., Eduardo; Rivera, Gonzalo; Echevarría, Ghislaine C.; Prylutskyy, Zakhar; Perez, Jordi; Ingelmo, Pablo
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    Intra-operative lidocaine in the prevention of vomiting after elective tonsillectomy in children
    (2018) Echevarría, Ghislaine C.; Altermatt, Fernando; Paredes, S.; Puga, V.; Auad, H.; Veloso, A.; Elgueta Le-Beuffe, María Francisca
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    Lysophosphatidic acid and apolipoprotein A1 predict increased risk of developing World Trade Center-lung injury : a nested case-control study
    (2014) Tsukiji, J.; Cho, S.; Kwon, S.; Echevarría, Ghislaine C.; Joseph, P.; Schenck, E.; Naveed, B.; Prezant, D.
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    One airway: Biomarkers of protection from upper and lower airway injury after World Trade Center exposure
    (2014) Cho, Soo Jung; Echevarría, Ghislaine C.; Kwon, Sophia; Naveed, Bushra; Schenck, Edward J.; Tsukiji, Jun; Rom, William N.; Prezant, David J.; Nolan, Anna; Weiden, Michael D.
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    The relationship between neuraxial anesthesia and advanced ovarian cancer-related outcomes in the chilean population
    (2013) Lacassie Quiroga, Héctor; Cartagena, J.; Brañes, Jorge; Assel, M.; Echevarría, Ghislaine C.
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    Validation and piloting of direct observation of practical skills tool to assess intubation in the Chilean context
    (2013) Delfino, Alejandro; Chandratilake, M.; Altermatt, Fernando; Echevarría, Ghislaine C.
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    Which types of peripheral nerve blocks should be included in residency training programs?
    (2015) Corvetto Aqueveque, Marcia Antonia; Echevarría, Ghislaine C.; Altermatt, Fernando; Espinoza, Ana M.; Corvetto Aqueveque, Marcia Antonia; Echevarria, Ghislaine C.; Altermatt, Fernando; Espinoza, Ana M.
    Abstract Background Despite the increasing use of regional anesthesia, specific recommendations regarding the type of procedures to be included in residency training programs are not currently available. We aimed to determine the nerve block techniques that practicing Chilean anesthesiologists perceived as essential to master during residency training. Methods After institutional ethics committee approval, an online survey was sent to 154 anesthesiologists that graduated between 2005–2012, from the two largest university residency programs in Chile. Multiple-choice questions elicited responses concerning the use of regional anesthesia. Results A total of 109 questionnaires were completed, which corresponded to a response rate of 70.8%. Almost all (98.2%) of the respondents used regional anesthesia in their clinical practice, 86.7% regularly performed peripheral nerve blocks (PNBs) and 51% used continuous PNB techniques. Residency programs represented their primary source of training. The most common PNB techniques performed were interscalene (100%), femoral (98%), popliteal sciatic (93%), and Bier block (90%). Respondents indicated that they were most confident performing femoral (98%), Bier block (90%), interscalene (90%), and popliteal sciatic (85%) blocks. The PNBs perceived as essential for their actual clinical practice were femoral (81%), interscalene (80%), popliteal sciatic (76%), and Bier blocks (62%). Conclusions Requesting information from former anesthesiology residents may be a source of information, guiding the specific types of PNBs that should be included in residency training. Other groups can easily replicate this methodology to create their own evidence and clinical practice based guidelines for residency training programs.Abstract Background Despite the increasing use of regional anesthesia, specific recommendations regarding the type of procedures to be included in residency training programs are not currently available. We aimed to determine the nerve block techniques that practicing Chilean anesthesiologists perceived as essential to master during residency training. Methods After institutional ethics committee approval, an online survey was sent to 154 anesthesiologists that graduated between 2005–2012, from the two largest university residency programs in Chile. Multiple-choice questions elicited responses concerning the use of regional anesthesia. Results A total of 109 questionnaires were completed, which corresponded to a response rate of 70.8%. Almost all (98.2%) of the respondents used regional anesthesia in their clinical practice, 86.7% regularly performed peripheral nerve blocks (PNBs) and 51% used continuous PNB techniques. Residency programs represented their primary source of training. The most common PNB techniques performed were interscalene (100%), femoral (98%), popliteal sciatic (93%), and Bier block (90%). Respondents indicated that they were most confident performing femoral (98%), Bier block (90%), interscalene (90%), and popliteal sciatic (85%) blocks. The PNBs perceived as essential for their actual clinical practice were femoral (81%), interscalene (80%), popliteal sciatic (76%), and Bier blocks (62%). Conclusions Requesting information from former anesthesiology residents may be a source of information, guiding the specific types of PNBs that should be included in residency training. Other groups can easily replicate this methodology to create their own evidence and clinical practice based guidelines for residency training programs.Abstract Background Despite the increasing use of regional anesthesia, specific recommendations regarding the type of procedures to be included in residency training programs are not currently available. We aimed to determine the nerve block techniques that practicing Chilean anesthesiologists perceived as essential to master during residency training. Methods After institutional ethics committee approval, an online survey was sent to 154 anesthesiologists that graduated between 2005–2012, from the two largest university residency programs in Chile. Multiple-choice questions elicited responses concerning the use of regional anesthesia. Results A total of 109 questionnaires were completed, which corresponded to a response rate of 70.8%. Almost all (98.2%) of the respondents used regional anesthesia in their clinical practice, 86.7% regularly performed peripheral nerve blocks (PNBs) and 51% used continuous PNB techniques. Residency programs represented their primary source of training. The most common PNB techniques performed were interscalene (100%), femoral (98%), popliteal sciatic (93%), and Bier block (90%). Respondents indicated that they were most confident performing femoral (98%), Bier block (90%), interscalene (90%), and popliteal sciatic (85%) blocks. The PNBs perceived as essential for their actual clinical practice were femoral (81%), interscalene (80%), popliteal sciatic (76%), and Bier blocks (62%). Conclusions Requesting information from former anesthesiology residents may be a source of information, guiding the specific types of PNBs that should be included in residency training. Other groups can easily replicate this methodology to create their own evidence and clinical practice based guidelines for residency training programs.Abstract Background Despite the increasing use of regional anesthesia, specific recommendations regarding the type of procedures to be included in residency training programs are not currently available. We aimed to determine the nerve block techniques that practicing Chilean anesthesiologists perceived as essential to master during residency training. Methods After institutional ethics committee approval, an online survey was sent to 154 anesthesiologists that graduated between 2005–2012, from the two largest university residency programs in Chile. Multiple-choice questions elicited responses concerning the use of regional anesthesia. Results A total of 109 questionnaires were completed, which corresponded to a response rate of 70.8%. Almost all (98.2%) of the respondents used regional anesthesia in their clinical practice, 86.7% regularly performed peripheral nerve blocks (PNBs) and 51% used continuous PNB techniques. Residency programs represented their primary source of training. The most common PNB techniques performed were interscalene (100%), femoral (98%), popliteal sciatic (93%), and Bier block (90%). Respondents indicated that they were most confident performing femoral (98%), Bier block (90%), interscalene (90%), and popliteal sciatic (85%) blocks. The PNBs perceived as essential for their actual clinical practice were femoral (81%), interscalene (80%), popliteal sciatic (76%), and Bier blocks (62%). Conclusions Requesting information from former anesthesiology residents may be a source of information, guiding the specific types of PNBs that should be included in residency training. Other groups can easily replicate this methodology to create their own evidence and clinical practice based guidelines for residency training programs.Abstract Background Despite the increasing use of regional anesthesia, specific recommendations regarding the type of procedures to be included in residency training programs are not currently available. We aimed to determine the nerve block techniques that practicing Chilean anesthesiologists perceived as essential to master during residency training. Methods After institutional ethics committee approval, an online survey was sent to 154 anesthesiologists that graduated between 2005–2012, from the two largest university residency programs in Chile. Multiple-choice questions elicited responses concerning the use of regional anesthesia. Results A total of 109 questionnaires were completed, which corresponded to a response rate of 70.8%. Almost all (98.2%) of the respondents used regional anesthesia in their clinical practice, 86.7% regularly performed peripheral nerve blocks (PNBs) and 51% used continuous PNB techniques. Residency programs represented their primary source of training. The most common PNB techniques performed were interscalene (100%), femoral (98%), popliteal sciatic (93%), and Bier block (90%). Respondents indicated that they were most confident performing femoral (98%), Bier block (90%), interscalene (90%), and popliteal sciatic (85%) blocks. The PNBs perceived as essential for their actual clinical practice were femoral (81%), interscalene (80%), popliteal sciatic (76%), and Bier blocks (62%). Conclusions Requesting information from former anesthesiology residents may be a source of information, guiding the specific types of PNBs that should be included in residency training. Other groups can easily replicate this methodology to create their own evidence and clinical practice based guidelines for residency training programs.
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    World Health Organization (WHO) surgical safety checklist implementation and its impact on perioperative morbidity and mortality in an academic medical center in Chile
    (2016) Lacassie Quiroga, Héctor; Ferdinand Olivares, Constanza; Guzmán, Sergio; Camus Bustos, Lorena Beatriz; Echevarría, Ghislaine C.