Browsing by Author "Duarte, L."
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- Itemn-3 polyunsaturated fatty acids in the regulation of adipose tissue browning and thermogenesis in obesity: Potential relationship with gut microbiota(2021) Zapata, J.; Gallardo, A.; Romero, C.; Valenzuela, R.; Garcia-Diaz, D. F.; Duarte, L.; Bustamante, A.; Gasaly, N.; Gotteland, M.; Echeverría González, Francisca CeciliaBackground: Obesity is a worldwide public health problem characterized by fat tissue accumulation, favouring adipose tissue and metabolic alterations. Increasing energy expenditure (EE) through brown adipose tissue activation and white adipose tissue (WAT) browning has gained relevance as a therapeutic approach. Different bioactive compounds, such as n-3 polyunsaturated fatty acids (PUFA), have been shown to induce those thermogenic effects. This process is regulated by the gut microbiota as well. Nevertheless, obesity is characterized by gut microbiota dysbiosis, which can be restored by weight loss and n-3 PUFA intake, among other factors. Knowledge gap: However, the role of the gut microbiota on the n-3 PUFA effect in inducing thermogenesis in obesity has not been fully elucidated. Objective: This review aims to elucidate the potential implications of this interrelation on WAT browning adiposw sittue (BAT), BAT activity, and EE regulation in obesity models.
- ItemNumerical computation of infragravity wave dynamics and velocity profiles using a fully nonlinear Boussinesq model(2010) Cienfuegos Carrasco, Rodrigo Alberto; Duarte, L.; Suarez, L.; Catalán, P.A.We present experimental and numerical analysis of nonlinear processes responsible for generating infragravity waves in the nearshore. We provide new experimental data on random wave propagation and associated velocity profiles in the shoaling and surf zones of a very mild slope beach. We analyze low frequency wave generation mechanisms and dynamics along the beach and examine in detail the ability of the fully nonlinear Boussinesq- type model SERR1D (Cienfuegos et al., 2010) to reproduce the complex dynamics of high frequency wave propagation and energy transfer mechanisms that enhance infragravity wave generation in the laboratory.
- ItemPhenomenology of scotogenic scalar dark matter(2020) Maturana Ávila, Ivania; De Romeri, V.; Duarte, L.; Valle, J. W. F.