Browsing by Author "Bertrand N., Pablo"
Now showing 1 - 9 of 9
Results Per Page
Sort Options
- ItemActividad física y obesidad en niños con asma(2007) Brockmann Veloso, Pablo Edmundo; Caussade Larraín, Marie Solange; Holmgren Palmen, Nils Linus Anders; Prado Atlogic, Francisco Javier; Reyes M., Bernardita; Viviani García, Paola; Bertrand N., PabloExercise- induced asthma is frequent among children. Objective: To compare physical activity (PA) and nutritional status in asthmatic (A) versus healthy (H) children. Methods: 81 school children were enrolled (40 A and 41 H). A validated interview with opinions and attitude towards PA was performed to parents in both groups. Nutritional status was classified according to body mass index. Answers were associated with χ2 test. Results: 44% girls, average age 9 years-old. Average hours per week of PA = 2.4 in H and 1.9 in A (p=NS); 88% of A versus 56% of H performed < 2 hours per week of PA (p < 0.05). 85% of A reported frequent symptoms associated to PA. Overweight and obesity were diagnosed in 15/40 A and 11/41 H (p < 0.05). Parents of A thought that PA was "dangerous" more frequently than parents of H (p < 0.05). Conclusions: Asthmatic children practice less PA than recommendations. There is an association between asthma, obesity and less PA level. Parents of asthmatic children have a negative opinion about PA, explaining the diminished PA performed by this group.
- ItemAtresia Esofágica y Fístula Traqueoesofágica. Evolución y Complicaciones Postquirúrgicas(2010) Jakubson S., Leticia; Paz C., Fernando; Zavala Busquets, Alejandro Luis; Harris D., Paul R.; Bertrand N., PabloLa Atresia esofágica (AE) con o sin fístula traqueoesofágica (FTE) es una malformación congénita que se asocia a complicaciones respiratorias y digestivas. Objetivo: Describir las características de estos pacientes, su morbilidad respiratoria, digestiva y hospitalizaciones en su evolución a largo plazo. Materiales y Métodos: Se revisaron en forma retrospectiva 15 fi chas de pacientes con diagnóstico de FTE evaluados por el equipo de Neumología Pediátrica de la Universidad Católica de Chile entre 1995 y 2007. Resultados: N = 15 pacientes, sexo masculino 9 diagnóstico el primer día de vida 13/15 pacientes. Clasifi cación de Gross: A= 0, B= 0, C= 12, D= 2, E= 1. Clasifi cación de Waterston A1: 6, B1: 1, B2: 4 y C2: 4 Malformaciones asociadas: en 7/15. Complicaciones respiratorias: Neumonía recurrente 8/15, sibilancias recurrentes 12/15, Recurrencia de fístula: 3 /15 pacientes, Apnea: 1 paciente, Traqueomalacia (TM) (9/15). Complicaciones digestivas: Refl ujo gastroesofágico 15/15, Estenosis esofágica: 7/ 15. Un paciente requirió cirugía de Nissen. Todos los pacientes se hospitalizaron en al menos una oportunidad y en el 12/15 la causa fue respiratoria. Conclusión: La FTE es una enfermedad de resolución quirúrgica con alta morbilidad respiratoria, digestiva y frecuentes hospitalizaciones en los primeros años de vida.
- ItemIdentification of biomarkers for disease severity in nasopharyngeal secretions of infants with upper or lower respiratory tract viral infectionsBertrand N., Pablo; Vazquez, Yaneisi; Beckhaus, Andrea A.; González Carreño, Liliana Andrea; Contreras Sepúlveda, Ana María; Ferrés Garrido, Marcela Viviana; Padilla Pérez, Oslando; Riedel, Claudia A.; Kalergis Parra, Alexis Mikes; Bueno, Susan M.Lower respiratory tract infections (LRTIs) produced by viruses are the most frequent cause of morbidity and mortality in children younger than 5 years of age. The immune response triggered by viral infection can induce a strong inflammation in the airways and cytokines could be considered as biomarkers for disease severity as these molecules modulate the inflammatory response that defines the outcome of patients. Aiming to predict the severity of disease during respiratory tract infections, we conducted a 1-year follow-up observational study in infants who presented upper or lower respiratory tract infections caused by seasonal respiratory viruses. At the time of enrollment, nasopharyngeal swabs (NPS) were obtained from infants to measure mRNA expression and protein levels of IL-3, IL-8, IL-33, and thymic stromal lymphopoietin. While all cytokines significantly increased their protein levels in infants with upper and lower respiratory tract infections as compared to control infants, IL-33 and IL-8 showed a significant increase in respiratory syncytial virus (RSV)-infected patients with LRTI as compared to patients with upper respiratory tract infection. We also found higher viral loads of RSV-positive samples with a greater IL-8 response at the beginning of the symptoms. Data obtained in this study suggest that both IL-8 and IL-33 could be used as biomarkers for clinical severity for infants suffering from LRTIs caused by the RSV.
- ItemSíndrome de muerte súbita del lactante: prevalencia y cambios en los últimos años en Chile(2013) Brockmann Veloso, Pablo Edmundo; Oyarzún Andrade, María Angélica; Villarroel del Pino, Luis A.; Bertrand N., PabloBackground: The sudden infant's death syndrome (SD) is the leading cause of death in children under one year. Despite advances in its study, the pathogenesis has not been yet fully elucidated. Aim: To assess the prevalence of SD in Chilean infants and its changes in recent years. Material and Methods: Review of birth and death databases of the Ministry of Health from 1997 to 2009. All cases diagnosed as SD, according to the International Classification of Diseases, 10th edition, were selected. A demographic analysis was performed and mortality rates for each year were calculated. Results: We identified 1442 cases of SD (847 males, 517 deaths at home). The median age of death was 2 months (0 to 11.0 months). Ninety six percent of deaths occurred in children aged <6 months. Mortality rate for SD was 0.45/1000 live births. There was a 23% reduction between 1997 and 2009. When analyzing geographic distribution, more cases were found in the Southern latitudes of the country. Conclusions: The overall rate of SD in Chile is higher than in European countries and in North America. The observed decrease in cases over the years is still far from optimal.
- ItemUso de los marcadores moleculares IL-3, IL-33 e IL-12p40 para caracterizar la severidad de infecciones respiratorias por virus respiratorio sincicial y metapneumovirus humanoBueno Ramírez, Susan; Kalergis Parra, Alexis Mikes; Bertrand N., Pablo; Lay, Margarita K.
- ItemUso de los marcadores moleculares IL-3, IL-33, IL-12p40 para caracterizar la severidad de infecciones respiratorias por virus respiratorio sincicial y metapneumovirus humano (China)Bueno Ramírez, Susan; Kalergis Parra, Alexis Mikes; Bertrand N., Pablo; Lay, Margarita K.
- ItemUso de los marcadores moleculares IL-3, IL-33, IL-12p40 para caracterizar la severidad de infecciones respiratorias por virus respiratorio sincicial y metapneumovirus humano (Países bajos, concesión n° 3329019)Bueno Ramírez, Susan; Kalergis Parra, Alexis Mikes; Bertrand N., Pablo; Lay, Margarita K.
- ItemUso de los marcadores moleculares IL-3, IL-33, IL-12p40 para caracterizar la severidad de infecciones respiratorias por virus respiratorio sincicial y metapneumovirus humano (USA)Bueno Ramírez, Susan; Kalergis Parra, Alexis Mikes; Bertrand N., Pablo; Lay, Margarita K.
- ItemUSO DE MARCADORES MOLECULARES IL-3, IL-33 E IL-12P40 PARA CARACTERIZAR AS GRAVIDADES DAS INFECÇÕES RESPIRATÓRIAS POR VÍRUS RESPIRATÓRIO SINCITIAL E METAPNEUMOVÍRUS HUMANO (Brasil, concesión n° 1120180021407)Bueno Ramírez, Susan; Kalergis Parra, Alexis Mikes; Bertrand N., Pablo; Lay, Margarita K.