Browsing by Author "Andrade Andrade, David Cristóbal"
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- ItemAblation of brainstem C1 neurons improves cardiac function in volume overload heart failure(2019) Andrade Andrade, David Cristóbal; Toledo, Camilo; Díaz, Hugo S.; Lucero, Claudia; Arce Álvarez, Alexis; Oliveira, Luis M.; Takakura, Ana C.; Moreira, Thiago S.; Schultz, Harold D.; Del Rio, Rodrigo; Marcus, Noah J.; Alcayaga Urbina, Julio Andrés
- ItemAcute effects of high-intensity interval training session and endurance e8xercise on pulmonary function and cardiorespiratory coupling(2020) Andrade Andrade, David Cristóbal; Arce Álvarez, Alexis; Parada, Felipe; Uribe, Sebastián; Gordillo, Pamela; Dupré, Anita; Ojeda, Carla; Palumbo, Fiorella; Castro, Guillermo; Vásquez Muñoz, Manuel; Del Rio, Rodrigo; Ramírez Campillo, Rodrigo; Izquierdo, Mikel
- ItemAcute Effects of Systemic Erythropoietin Injections on Carotid Body Chemosensory Activity Following Hypoxic and Hypercapnic Stimulation(2018) Andrade Andrade, David Cristóbal; Iturriaga Agüera, Rodrigo; Jeton, Florine; Alcayaga Urbina, Julio Andrés; Voituron, Nicolas; Del Rio, Rodrigo
- ItemBaroreflex Modulation During Acute High-Altitude Exposure in Rats(2020) Beltrán, A. R.; Arce Alvarez, A.; Ramírez Campillo, R.; Vásquez Muñoz, M.; Von Igel, M.; Ramírez, M. A.; Río, R. del; Andrade Andrade, David Cristóbal
- ItemBenefits of oxytocin administration in obstructive sleep apnea(2017) Jain, Vivek; Marbach, Joseph; Kimbro, Shawn; Andrade Andrade, David Cristóbal; Jain, Arad; Capozzi, Eleanor; Mele, Kyle; Del Rio, Rodrigo; Kay, Matthew W.; Mendelowitz, David
- ItemCardiac remodeling and arrhythmogenesis are ameliorated by administration of Cx43 mimetic peptide Gap27 in heart failure rats(2020) Lucero, C. M.; Andrade Andrade, David Cristóbal; Toledo, C.; Diaz, H. S.; Pereyra, K. V.; Díaz Jara, Esteban; Schwarz Flores, Karla Gabriele; Marcus, N. J.; Retamal, M. A.; Quintanilla Gómez, Rodrigo Arthur; Del Río, R.
- ItemCarotid Body-Mediated Chemoreflex Drive in the Setting of low and High Output Heart Failure(2017) Del Río, R.; Andrade Andrade, David Cristóbal; Toledo, C.; Díaz, H.|Lucero, C.; Arce Álvarez, A.; Marcus, N.; Schultz, H.
- ItemCognitive impairment in heart failure is associated with altered Wnt signaling in the hippocampus(2019) Toledo, C.; Lucero, C.; Andrade Andrade, David Cristóbal; Diaz, H.S.; Schwarz Flores, Karla Gabriele; Pereyra, K.V.; Arce-Alvarez, A.; Lopez, N.A.; Martinez, M.; Inestrosa Cantín, Nibaldo; Del Rio, R.
- ItemCOMMENT ON "PRECEDENCE AND AUTOCRACY IN BREATHING CONTROL"(2015) Del Río, R.; Andrade Andrade, David Cristóbal
- ItemCorrection to : Effects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure(2022) Schwarz Flores, Karla Gabriele; Pereyra Florián, Katherin Vanessa; Toledo, Camilo; Andrade Andrade, David Cristóbal; Díaz, Hugo S.; Díaz Jara, Esteban; Ortolani, Domiziana; Ríos Gallardo, Angélica; Arias, Paulina; Las Heras, AlexandraAn amendment to this paper has been published and can be accessed via the original article.
- ItemCrucial Role of the Carotid Body Chemoreceptors on the Development of High Arterial Blood Pressure During Chronic Intermittent Hypoxia(2015) Iturriaga Agüera, Rodrigo; Andrade Andrade, David Cristóbal
- ItemDietary supplementation of a sulforaphane-enriched broccoli extract protects the heart from acute cardiac stress(2020) Pereyra Florián, Katherin Vanessa; Andrade Andrade, David Cristóbal; Toledo, C.; Schwarz Flores, Karla Gabriele; Uribe-Ojeda, A.; Ríos-Gallardo, A. P.; Quintanilla, Rodrigo A.; Contreras E., Samuel; Mahn, A.; Río Troncoso, Rodrigo Andre del
- ItemEffects of enriched-potassium diet on cardiorespiratory outcomes in experimental non-ischemic chronic heart failure(2021) Schwarz Flores, Karla Gabriele; Pereyra Florián, Katherin Vanessa; Toledo, Camilo; Andrade Andrade, David Cristóbal; Díaz, Hugo S.; Díaz Jara, Esteban; Ortiz Cisternas, Fernando Andrés; Inestrosa Cantín, Nibaldo; Vio Lagos, Carlos P.; Río Troncoso, Rodrigo Andre delChronic heart failure (CHF) is a global health problem. Increased sympathetic outfow, cardiac arrhythmogenesis and irregular breathing patterns have all been associated with poor outcomes in CHF. Several studies showed that activation of the renin-angiotensin system (RAS) play a key role in CHF pathophysiology. Interestingly, potassium (K+) supplemented diets showed promising results in normalizing RAS axis and autonomic dysfunction in vascular diseases, lowering cardiovascular risk. Whether subtle increases in dietary K+ consumption may exert similar efects in CHF has not been previously tested. Accordingly, we aimed to evaluate the efects of dietary K+ supplementation on cardiorespiratory alterations in rats with CHF. Methods: Adult male Sprague–Dawley rats underwent volume overload to induce non-ischemic CHF. Animals were randomly allocated to normal chow diet (CHF group) or supplemented K+ diet (CHF+K+ group) for 6 weeks. Cardiac arrhythmogenesis, sympathetic outfow, barorefex sensitivity, breathing disorders, chemorefex function, respiratory–cardiovascular coupling and cardiac function were evaluated. Results: Compared to normal chow diet, K+ supplemented diet in CHF signifcantly reduced arrhythmia incidence (67.8±15.1 vs. 31.0±3.7 events/hour, CHF vs. CHF+K+), decreased cardiac sympathetic tone (ΔHR to propranolol: −97.4±9.4 vs. −60.8±8.3 bpm, CHF vs. CHF+K+), restored barorefex function and attenuated irregular breathing patterns. Additionally, supplementation of the diet with K+ restores normal central respiratory chemorefex drive and abrogates pathological cardio-respiratory coupling in CHF rats being the outcome an improved cardiac function. Conclusion: Our fndings support that dietary K+ supplementation in non-ischemic CHF alleviate cardiorespiratory dysfunction.
- ItemEffects of plyometric training on explosive and endurance performance at sea level and at high altitude(2018) Andrade Andrade, David Cristóbal; Beltrán, Ana Rosa; Labarca Valenzuela, Cristian; Manzo Botarelli, Oscar; Trujillo, Erwin; Otero Farias, Patricio; Álvarez, Cristian; Garcia Hermoso, Antonio; Toledo, Camilo; Del Río, Rodrigo |Silva Urra, Juan; Ramírez Campillo, Rodrigo
- ItemEnhanced carotid body chemosensory activity and the cardiovascular alterations induced by intermittent hypoxia(2014) Iturriaga Agüera, Rodrigo; Andrade Andrade, David Cristóbal
- ItemEpisodic stimulation of central chemoreceptor neurons elicits disordered breathing and autonomic dysfunction in volume overload heart failure(2020) Diaz, HS; Andrade Andrade, David Cristóbal; Toledo, C; Pereyra, KV; Schwarz Flores, Karla Gabriele; Díaz Jara, Esteban; Lucero, C; Arce-Alvarez, A; Schultz, HD; Silva, JN; Takakura, AC; Moreira, TS; Marcus, NJ; Del Rio, R
- ItemExercise training improves cardiac autonomic control, cardiac function, and arrhythmogenesis in rats with preserved-ejection fraction heart failure(2017) Andrade Andrade, David Cristóbal; Arce-Alvarez Alexis; Toledo Camilo; Díaz Hugo S.; Lucero Claudia; Schultz Harold D.; Marcus Noah J.; Del Rio, Rodrigo
- ItemHeart rate and cardiac autonomic responses to concomitant deep breathing, hand grip exercise, and circulatory occlusion in healthy young adult men and women(2021) Andrade Andrade, David Cristóbal; Melipillan, Claudia; Toledo, Camilo; Rios-Gallardo, Angélica; Marcus, Noah J.; Ortiz, Fernando C.; Martinez, Gonzalo; Muñoz Venturelli, Paula; Río Troncoso, Rodrigo Andre delBackground: Deep breathing (DB) and handgrip (HG) exercise -with and without circulatory occlusion (OC) in muscle-, have been shown to have beneficial effects on cardiovascular function; however, the combination of these maneuvers on heart rate (HR) and cardiac sympathovagal balance have not been previously investigated. Therefore, the aim of the present study was to evaluate the effect of simultaneous DB, HG, and OC maneuvers on the sympathovagal balance in healthy women and men subjects. Methods and results: Electrocardiogram and ventilation were measured in 20 healthy subjects (Women: n = 10; age = 27 ± 4 years; weight = 67.1 ± 8.4 kg; and height = 1.6 ± 0.1 m. Men: n = 10; age = 27 ± 3 years; weight = 77.5 ± 10.1 kg; and height = 1.7 ± 0.1 m) at baseline and during DB, DB + HG, or DB + HG + OC protocols. Heart rate (HR) and respiratory rate were continuously recorded, and spectral analysis of heart rate variability (HRV) were calculated to indirectly estimate cardiac autonomic function. Men and women showed similar HR responses to DB, DB + HG and DB + HG + OC. Men exhibited a significant HR decrease following DB + HG + OC protocol which was accompanied by an improvement in cardiac autonomic control evidenced by spectral changes in HRV towards parasympathetic predominance (HRV High frequency: 83.95 ± 1.45 vs. 81.87 ± 1.50 n.u., DB + HG + OC vs. baseline; p < 0.05). In women, there was a marked decrease in HR after completion of both DB + HG and DB + HG + OC tests which was accompanied by a significant increase in cardiac vagal tone (HRV High frequency: 85.29 ± 1.19 vs. 77.93 ± 0.92 n.u., DB + HG vs. baseline; p < 0.05). No adverse effects or discomfort were reported by men or women during experimental procedures. Independent of sex, combination of DB, HG, and OC was tolerable and resulted in decreases in resting HR and elevations in cardiac parasympathetic tone. Conclusions: These data indicate that combined DB, HG and OC are effective in altering cardiac sympathovagal balance and reducing resting HR in healthy men and women.
- ItemHeart rate variability alterations in infants with spontaneous hypertonia(2019) Arce-Alvarez, A.; Melipillan, C.; Andrade Andrade, David Cristóbal; Toledo, C.; Marcus, N.J.; Del Rio, R.
- ItemHigh-speed resistance training is more effective than low-speed resistance training to increase functional capacity and muscle performance in older women(2014) Ramírez-Campillo, Rodrigo; Castillo, Angélica; De la Fuente, Carlos; Campos Jara, Christian Alex; Andrade Andrade, David Cristóbal; Álvarez, Cristian; Martínez Belmar, Cristian Antonio; Castro Sepúlveda, Mauricio; Pereira, Ana; Marques, Mário C.; Izquierdo, Mikel