Browsing by Author "Viteri Espinoza, Rafael Antonio"

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    Bioactive compounds in Apis mellifera monofloral honeys
    (2021) Viteri Espinoza, Rafael Antonio; Zacconi, Flavia C. M.; Montenegro Rizzardini, Gloria; Giordano Villatoro, Ady Iveth
    Honey is a natural product with a sweet flavor. Honey is made by the honeybee (Apis mellifera L.) from the nectar of flowers or other plant secretions that are collected near the hive. These products are mixed with bee saliva and stored. Several studies have demonstrated that honey exhibits antioxidant, antimicrobial, nematicidal, antifungal, anticancer, and anti-inflammatory activities. These properties are influenced by the plants from which the secretions are harvested, from the naturally occurring compounds present in the nectar. Studies of the properties and applications of honey have distinguished honey from other natural products due to the presence of certain compounds and due its bioactive properties. The focus of this review is to discuss the identified and isolated compounds from monofloral honey produced by A. mellifera, with specific emphasis on antioxidant and antimicrobial properties of honey and its therapeutic health benefits.
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    Flavonoids and triterpenes isolated from Eucryphia cordifolia (Cunoniaceae)
    (2022) Viteri Espinoza, Rafael Antonio; Giordano Villatoro, Ady; Montenegro Rizzardini, Gloria; Zacconi, Flavia C. M.
    The phytochemical study of the leaves of Eucryphia cordifolia (Cunoniaceae) allowed for the isolation of six compounds: the triterpenes betulin (1) and 28-acetoxy betulin (3), the steroid β-sitosterol (2), the flavonol quercetrin (4), the flavanonol astilbine (5) and the flavanol catechin (6). The structures of the isolated compounds were clearly assigned through 1D and 2D-NMR, MS studies, and compared to previously described data. This is the first report on the isolation of compounds 1–4 and 6 from the genus Eucryphia. The chemotaxonomic importance of the isolated compounds within the family of Cunoniaceae-related plants is discussed.
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    Metabolomic Profiling and Antioxidant Properties of Chilean Eucryphia cordifolia Cav.: Insights from Leaves, Flowers, and Monofloral Honey
    (2025) Viteri Espinoza, Rafael Antonio; Giordano Villatoro, Ady; Montenegro Rizzardini, Gloria; Simirgiotis, Mario J.; Zacconi, Flavia C. M.
    This study aimed to characterize the metabolomic profile of monofloral honey from Eucryphia cordifolia (ulmo) and evaluate the potential transfer of bioactive compounds from the plant parts, including the leaves and flowers, to the honey. Using UHPLC/ Q-TOF-MS analysis, various flavonoids and phenolic acids were identified and quantified in extracts from the leaves, flowers, and honey from E. cordifolia. Given their rich polypheAcademicEditor: Elisabeta Irina Geana Received: 11January2025 Revised: 24February2025 Accepted: 26February2025 Published: 28 February2025 Citation: Viteri, R.; Giordano, A.; Montenegro,G.;Simirgiotis, M.J.; Zacconi, F.C. MetabolomicProfiling andAntioxidantProperties ofChilean Eucryphia cordifolia Cav.: Insights from Leaves, Flowers, andMonofloral Honey. Antioxidants 2025, 14, 292. https://doi.org/10.3390/ antiox14030292 Copyright: ©2025bytheauthors. Licensee MDPI,Basel,Switzerland. This article is an open access article distributed under the termsand conditions of the Creative Commons Attribution (CC BY)license (https://creativecommons.org/ licenses/by/4.0/). nolic composition, E. cordifolia leaves were included in this study to assess their potential contribution to the antioxidant properties and chemical markers of ulmo honey. Additionally, the polyphenolic compounds in honey samples were quantified. Chromatographic analysis via UHPLC-MS/MS revealed that ulmo honey contains phenolic acids such as gallic, syringic, ferulic, chlorogenic, caffeic, and coumaric acid, as well as flavonoids including pinocembrin, quercetin, luteolin, kaempferol, epicatechin, apigenin, and isorhamnetin. The results indicate that pinocembrin and gallic acid are the main chemical markers of ulmo honey, while isorhamnetin could complement its characterization as a complementary marker. UHPLC/Q-TOF-MS analysis was also utilized to compare the compounds present in the honey with those found in the plant parts (leaves and flowers), respectively. A total of 10 shared compounds were identified, 9 of which were preliminarily identified, while 1remainsunknown. Notably,dihydroquercetin3-O-rhamnoside,quercetin3-O-rhamnoside, cyanidin 3-(p-coumaroyl)-glucoside, and eupatorin were detected in ulmo honey for the f irst time. Along with gallic acid, pinocembrin, and isorhamnetin, these compounds could contribute to a characteristic fingerprint for identifying the botanical origin of the honey. Overall, these findings provide valuable insights into the chemical composition of ulmo honey and its potential application as a functional product with antioxidant properties.