Browsing by Author "Urzúa Acevedo, Marcela del Pilar"
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- ItemAdsorption Behavior of Hydrophobically Modified Polyelectrolytes onto Amino- or Methyl-Terminated Surfaces(2011) Briones O., Ximena; Encinas, Maria V.; Petri, Denise F.S.; Pavez, Jorge E.; Tapia Apati, Ricardo; Yazdani-Pedram, M.; Urzúa Acevedo, Marcela del Pilar
- ItemBlends containing amphiphilic polymers VI. Compatibilization of N-alkylitaconamic acid-co-styrene copolymers with poly(hydroxypropyl methacrylate) and poly(4-vinylphenol)(2007) Urzúa Acevedo, Marcela del Pilar; Leiva Campusano, Ángel; Alegría Aguirre, Luz Katiushka; Gargallo Gómez, Ligia Teresita; Radić Foschino, Deodato D.
- ItemBlends containing amphiphilic polymers. V. Compatibilization of N-alkylitaconamic acid-co-styrene copolymers with interacting polymers(2006) Urzúa Acevedo, Marcela del Pilar; Sandoval, Claudia; Gonzalez-Nilo, Fernando; Leiva Campusano, Ángel; Gargallo Gómez, Ligia Teresita; Radić Foschino, Deodato D.
- ItemChromium retention properties of N-alkyl quaternized poly(4-vinylpyridine)(2009) Toral, Maria Ines; Gonzalez-Navarrete, Javier; Leiva Campusano, Ángel; Ríos, Hernán E.; Urzúa Acevedo, Marcela del Pilar
- ItemCopolymers of Phenoxyethyl Methacrylate with Butyl Methacrylate: Synthesis, Characterization and Reactivity Ratios(2009) Basha, Kottur Anver; Balakrishnan, Thavikkannu; Urzúa Acevedo, Marcela del Pilar; Leiva Campusano, Ángel; Alegría Aguirre, Luz Katiushka; Gargallo Gómez, Ligia Teresita; Radić Foschino, Deodato D.
- ItemCopolymers of Phenoxyethyl Methacrylate with Glycidyl Methacrylate: Synthesis, Characterization and Reactivity Ratios(2008) Basha, Kottur Anver; Balakrishnan, Thavikkannu; Urzúa Acevedo, Marcela del Pilar; Leiva Campusano, Ángel; Alegría Aguirre, Luz Katiushka; Gargallo Gómez, Ligia Teresita; Radić Foschino, Deodato D.
- ItemCopolymers of phenoxyethyl methacrylate with n-vinyl-2-pyrrolidone: Synthesis, characterization and reactivity ratios(2007) Basha, Kottur Anver; Balakrishnan, T.; Urzúa Acevedo, Marcela del Pilar; Leiva Campusano, Ángel; Gargallo Gómez, Ligia Teresita; Radić Foschino, Deodato D.
- ItemGold-copolymer nanoparticles: Poly(epsilon-caprolactone)/poly(N-vinyl-2-pyrrolydone) Biodegradable triblock copolymer as stabilizer and reductant(2009) Leiva Campusano, Ángel; Saldías, César; Quezada, Caterina; Toro Labbé, Alejandro; Espinoza-Beltran, Francisco J.; Urzúa Acevedo, Marcela del Pilar; Gargallo Gómez, Ligia Teresita; Radić Foschino, Deodato D.
- ItemInteraction energy in polymer blends containing N-1-alkylitaconamic acids moiety(2003) Gonzalez-Nilo, F.D.; Urzúa Acevedo, Marcela del Pilar; Leiva Campusano, Ángel; Gargallo Gómez, Ligia Teresita; Radić Foschino, Deodato D.
- ItemInterim report: Safety and immunogenicity of an inactivated vaccine against SARS-CoV-2 in healthy chilean adults in a phase 3 clinical trial(2021) Bueno Ramírez, Susan; Abarca Villaseca, Katia; González Adonis, Pablo Andrés; Gálvez Arriagada, Nicolás Marcelo Salvador; Soto Ramírez, Jorge Andrés; Duarte Peñaloza, Luisa Fernanda; Schultz Lombardic, Bárbara M.; Pacheco, Gaspar A.; González Carreño, Liliana Andrea; Vázquez, Yaneisi; Ríos Raggio, Mariana; Melo González, Felipe; Rivera Pérez, Daniela; Iturriaga, Carolina; Urzúa Acevedo, Marcela del Pilar; Domínguez De Landa, María Angélica; Andrade Parra, Catalina Andrea; Berríos Rojas, Roslye; Canedo Marroquín, Giselda; Covián, CamilaThe ongoing COVID-19 pandemic has had a significant impact worldwide, with an incommensurable social and economic burden. The rapid development of safe and protective vaccines against this disease is a global priority. CoronaVac is a vaccine prototype based on inactivated SARS-CoV-2, which has shown promising safety and immunogenicity profiles in pre-clinical studies and phase 1/2 trials in China. To this day, four phase 3 clinical trials are ongoing with CoronaVac in Brazil, Indonesia, Turkey, and Chile. This article reports the safety and immunogenicity results obtained in a subgroup of participants aged 18 years and older enrolled in the phase 3 Clinical Trial held in Chile.
- ItemPrevalence of filaggrin loss-of-function variants in Chilean population with and without atopic dermatitis(2021) Cárdenas, Geovanna V.; Iturriaga Ortiz, Carollina Alejandra; Hernández Vargas, Caroll Daffner; Tejos Bravo, Macarena; Perez Mateluna, Guillermo; Cabalín Arenas, Carolina Andrea; Urzúa Acevedo, Marcela del Pilar; Venegas Salas, Luis F.; Fraga Cerda, Juan Pablo; Borzutzky Schachter, Arturo; Pontificia Universidad Católica de Chile. Escuela de MedicinaBackground Filaggrin (FLG) loss-of-function variants are major genetic risk factors for atopic dermatitis (AD), but these have not been studied in Latin American populations with and without AD. Methods FLG variants R501X and 2282del4 were genotyped in 275 Chilean adults with and without AD from the “Early origins of allergy and asthma” (ARIES) cohort and in 227 patients from an AD cohort based in Santiago, Chile. Results Among adults in the ARIES cohort, 3.3% were carriers of R501X and 2.9% of 2282 del 4 variants, all heterozygotes. In this cohort, 6.2% were FLG variant carriers: 11.1% of subjects reporting AD were carriers of FLG variants vs. 5.2% in those without AD (P = 0.13). In this first cohort, FLG variants were not significantly associated with asthma, allergic rhinitis, or food allergy. In the AD cohort, the prevalence of FLG variants was 7% for R501X, 2.2% for the 2282del4 variant, and 9.3% for the combined genotype. In this cohort, FLG variants were present in 15.5% of severe AD vs. 7.1% of mild-to-moderate AD subjects (P = 0.056). Evaluation of Chilean population from both cohorts combined (n = 502) revealed that FLG variants were not significantly associated with AD (OR = 1.92 [95% CI 0.95–3.9], P = 0.067) but were associated with asthma (OR = 2.16 [95% CI 1.02–4.56], P = 0.039). Conclusions This is the first study to evaluate FLG loss-of-function variants R501X and 2282del4 in Latin American population, revealing a similar prevalence of these FLG variant carriers to that of European populations. Among Chileans, FLG variants were significantly associated with asthma but not AD.