Browsing by Author "Urquiaga Reus, Inés"
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- ItemA Chilean Berry Concentrate Protects against Postprandial Oxidative Stress and Increases Plasma Antioxidant Activity in Healthy Humans(2017) Urquiaga Reus, Inés; Avila, F.; Echeverría Errázuriz, Guadalupe; Pérez Pons, Druso Diego; Trejo, S.; Leighton, Federico
- ItemAntioxidant and anti hyperglycemic role of wine grape powder in rats fed with a high fructose diet(2015) Hernández-Salinas, Romina.; Decap, Valerie.; Leguina-Ruzzi, Alberto; Cáceres, Patricio.; Pérez, Druso.; Urquiaga Reus, Inés; Iturriaga Agüera, Rodrigo; Velarde Aliaga, María VictoriaAbstract Background Metabolic syndrome is a growing worldwide health problem. We evaluated the effects of wine grape powder (WGP), rich in antioxidants and fiber, in a rat model of metabolic syndrome induced by a high fructose diet. We tested whether WGP supplementation may prevent glucose intolerance and decrease oxidative stress in rats fed with a high fructose diet. Methods Male Sprague–Dawley rats weighing 180 g were divided into four groups according to their feeding protocols. Rats were fed with control diet (C), control plus 20 % WGP (C + WGP), 50 % high fructose (HF) or 50 % fructose plus 20 % WGP (HF + WGP) for 16 weeks. Blood glucose, insulin and triglycerides, weight, and arterial blood pressure were measured. Homeostasis model assessment (HOMA) index was calculated using insulin and glucose values. A glucose tolerance test was performed 2 days before the end of the experiment. As an index of oxidative stress, thiobarbituric acid reactive substances (TBARS) level was measured in plasma and kidney, and superoxide dismutase was measured in the kidney. Results Thiobarbituric acid reactive substances in plasma and renal tissue were significantly higher when compared to the control group. In addition, the area under the curve of the glucose tolerance test was higher in HF fed animals. Furthermore, fasting blood glucose, plasma insulin levels, and the HOMA index, were also increased. WGP supplementation prevented these alterations in rats fed with the HF diet. We did not find any significant difference in body weight or systolic blood pressure in any of the groups. Conclusions Our results show that WGP supplementation prevented hyperglycemia, insulin resistance and reduced oxidative stress in rats fed with HF diet. We propose that WGP may be used as a supplement in human food as well.Abstract Background Metabolic syndrome is a growing worldwide health problem. We evaluated the effects of wine grape powder (WGP), rich in antioxidants and fiber, in a rat model of metabolic syndrome induced by a high fructose diet. We tested whether WGP supplementation may prevent glucose intolerance and decrease oxidative stress in rats fed with a high fructose diet. Methods Male Sprague–Dawley rats weighing 180 g were divided into four groups according to their feeding protocols. Rats were fed with control diet (C), control plus 20 % WGP (C + WGP), 50 % high fructose (HF) or 50 % fructose plus 20 % WGP (HF + WGP) for 16 weeks. Blood glucose, insulin and triglycerides, weight, and arterial blood pressure were measured. Homeostasis model assessment (HOMA) index was calculated using insulin and glucose values. A glucose tolerance test was performed 2 days before the end of the experiment. As an index of oxidative stress, thiobarbituric acid reactive substances (TBARS) level was measured in plasma and kidney, and superoxide dismutase was measured in the kidney. Results Thiobarbituric acid reactive substances in plasma and renal tissue were significantly higher when compared to the control group. In addition, the area under the curve of the glucose tolerance test was higher in HF fed animals. Furthermore, fasting blood glucose, plasma insulin levels, and the HOMA index, were also increased. WGP supplementation prevented these alterations in rats fed with the HF diet. We did not find any significant difference in body weight or systolic blood pressure in any of the groups. Conclusions Our results show that WGP supplementation prevented hyperglycemia, insulin resistance and reduced oxidative stress in rats fed with HF diet. We propose that WGP may be used as a supplement in human food as well.Abstract Background Metabolic syndrome is a growing worldwide health problem. We evaluated the effects of wine grape powder (WGP), rich in antioxidants and fiber, in a rat model of metabolic syndrome induced by a high fructose diet. We tested whether WGP supplementation may prevent glucose intolerance and decrease oxidative stress in rats fed with a high fructose diet. Methods Male Sprague–Dawley rats weighing 180 g were divided into four groups according to their feeding protocols. Rats were fed with control diet (C), control plus 20 % WGP (C + WGP), 50 % high fructose (HF) or 50 % fructose plus 20 % WGP (HF + WGP) for 16 weeks. Blood glucose, insulin and triglycerides, weight, and arterial blood pressure were measured. Homeostasis model assessment (HOMA) index was calculated using insulin and glucose values. A glucose tolerance test was performed 2 days before the end of the experiment. As an index of oxidative stress, thiobarbituric acid reactive substances (TBARS) level was measured in plasma and kidney, and superoxide dismutase was measured in the kidney. Results Thiobarbituric acid reactive substances in plasma and renal tissue were significantly higher when compared to the control group. In addition, the area under the curve of the glucose tolerance test was higher in HF fed animals. Furthermore, fasting blood glucose, plasma insulin levels, and the HOMA index, were also increased. WGP supplementation prevented these alterations in rats fed with the HF diet. We did not find any significant difference in body weight or systolic blood pressure in any of the groups. Conclusions Our results show that WGP supplementation prevented hyperglycemia, insulin resistance and reduced oxidative stress in rats fed with HF diet. We propose that WGP may be used as a supplement in human food as well.
- ItemAssessment of the reliability of food labeling in Chile [¿Podemos confiar en el etiquetado nutricional de los alimentos en Chile?](2014) Urquiaga Reus, Inés; Echeverría Errázuriz, Guadalupe; Leighton, Federico
- ItemCurrent evidence on health benefits of the mediterranean diet(2016) Dussaillant, C.; Echeverria, G.; Urquiaga Reus, Inés; Velasco Fuentes, Nicolas; Rigotti Rivera, Attilio
- ItemEffect of Mediterranean and occidental diets, and red wine, on plasma fatty acids in humans. An intervention study(2004) Urquiaga Reus, Inés; Guasch Castro, Viviana; Marshall Rivera, Guillermo; San Martin, Alejandra; Castillo Valenzuela, Oscar; Rozowski Narkunska, Samuel Jaime; Leighton Puga, Federico
- ItemEffect of Mediterranean and Occidental Diets, and Red Wine, on Plasma Fatty Acids in Humans. An Intervention Study(2004) Urquiaga Reus, Inés; Marshall Rivera, Guillermo; Rozowski Narkunska, Samuel Jaime; Leighton, Federico
- ItemInverse Associations between a Locally Validated Mediterranean Diet Index, Overweight/Obesity, and Metabolic Syndrome in Chilean Adults(2017) Echeverria, G.; McGee, E.; Urquiaga Reus, Inés; Jimenez, P.; D’Acuña, S.; Villarroel del Pino, Luis A.; Velasco Fuentes, Nicolas; Leighton, Federico; Rigotti Rivera, Attilio
- ItemMediterranean diet and red wine protect against oxidative damage in young volunteers(ELSEVIER IRELAND LTD, 2010) Urquiaga Reus, Inés; Strobel Lobos, Pablo Alberto; Pérez Pons, Druso Diego; Martinez, Carlos; Cuevas Marin, Ada Marisa; Castillo Valenzuela, Oscar; Marshall Rivera, Guillermo; Rozowski Narkunska, Samuel Jaime; Leighton Puga, Federico
- ItemOrigen, componentes y posibles mecanismos de acción de la dieta mediterránea(2017) Urquiaga Reus, Inés; Echeverría Errázuriz, Guadalupe; Dussaillant, C.; Rigotti Rivera, Attilio
- ItemPlant Polyphenol Antioxidants and Oxidative Stress(2000) Urquiaga Reus, Inés; Leighton, Federico
- Item¿Podemos confiar en el etiquetado nutricional de los alimentos en Chile?(2014) Urquiaga Reus, Inés; Lamarca, M.; Jiménez, P.; Echeverría, G.; Leighton, Federico
- ItemRed wine grape pomace attenuates atherosclerosis and myocardial damage and increases survival in association with improved plasma antioxidant activity in a murine model of lethal ischemic heart disease(2019) Rivera Vega, Katherine Solange; Salas Pérez, Francisca Lorena; Echeverría Errázuriz, Guadalupe; Urquiaga Reus, Inés; Dicenta, Sara; Pérez Pons, Druso Diego; De La Cerda, Paula; Gonzáles, Leticia; Andía Kohnenkampf, Marcelo Edgardo; Uribe Arancibia, Sergio A.; Tejos Núñez, Cristián Andrés; Martínez, Gonzalo; Busso, Dolores; Irarrazaval, Pablo; Rigotti Rivera, Attilio
- ItemSerum Ferritin Is Associated with Metabolic Syndrome and Red Meat Consumption(2015) Ávila, Felipe; Echeverría Errázuriz, Guadalupe; Pérez, Druso; Martínez, Carlos; Strobel Lobos, Pablo Alberto; Castillo Valenzuela, Oscar; Villarroel del Pino, Luis A.; Mezzano, Diego; Rozowski Narkunska, Samuel Jaime; Urquiaga Reus, Inés; Leighton, Federico
- ItemThe Chilean diet and the omega-6/omega-3 balance(S.Karger AG, 2011) Leighton, Federico; Echeverría Errázuriz, Guadalupe; Urquiaga Reus, Inés
- ItemThe consumption of beef burgers prepared with wine grape pomace flour improves fasting glucose, plasma antioxidant levels, and oxidative damage markers in humans : a controlled trial(2018) Urquiaga Reus, Inés; Troncoso, Danitza; Mackenna, María José; Urzúa, Catalina; Pérez, Druso; Dicenta, Sara; De la Cerda, Paula María; Amigo, Ludwig; Carreño, Juan Carlos; Echeverría Errázuriz, Guadalupe; Rigotti Rivera, Attilio
- ItemValidación de cuestionario autoaplicable para un índice de alimentación mediterránea en Chile(2016) Echeverría Errázuriz, Guadalupe; Urquiaga Reus, Inés; Concha, María José; Dussaillant, Catalina; Villarroel del Pino, Luis A.; Velasco Fuentes, Nicolas; Leighton, Federico; Rigotti Rivera, Attilio
- ItemWine grape pomace flour improves blood pressure, fasting glucose and protein damage in humans: a randomized controlled trial(2015) Urquiaga Reus, Inés; D’Acuña, Sonia.; Pérez Pons, Druso Diego; Dicenta, Sara.; Echeverría Errázuriz, Guadalupe; Rigotti Rivera, Attilio; Leighton, FedericoAbstract Background The Mediterranean diet is a healthy diet with positive scientific evidence of preventing chronic diseases. Bioactive components support the healthy properties of the Mediterranean diet. Antioxidants and fiber, two components of the Mediterranean diet, are key functional nutrients for healthy eating and nutrition. Wine grape pomace is a rich source of these dietary constituents and may be beneficial for human health. Our hypothesis was that the intake of red wine grape pomace flour (WGPF) prepared from red wine grapes (Cabernet Sauvignon variety) reduced the metabolic syndrome in humans. To evaluate the effect of WGPF on components of metabolic syndrome we design a 16-week longitudinal intervention study. Thirty-eight males, 30–65 years of age, with at least one component of metabolic syndrome, were randomly assigned to either the intervention group (n = 25) or the control group (n = 13). At lunch, the intervention group was given 20 g of WGPF per day, which contained 10 g of dietary fiber, 822 mg of polyphenols and an antioxidant capacity of 7258 ORAC units. Both groups were asked to maintain their regular eating habits and lifestyles. Clinical evaluation, anthropometric measurements and biochemical blood analyses were done at the beginning and the end of the study. Results WGPF intake significantly decreased systolic and diastolic blood pressure as well as fasting glucose levels. Plasma γ-tocopherol and δ-tocopherol increased and carbonyl group in plasma protein decreased in WGPT group, significantly. No significant effect was observed for waist circumference, HDL cholesterol, triglycerides, total antioxidant capacity and vitamin C in and between groups. The group-dependent magnitude of the differences between the baseline and final postprandial insulin values and γ-tocopherol concentrations was statistically significant. Conclusions The consumption of WGPF-rich in fiber and polyphenol antioxidants, as a food supplement in a regular diet improves blood pressure, glycaemia and postprandial insulin. In addition, increased antioxidant defenses and decreased oxidative protein damage indicating attenuation of oxidative stress. WGPF might be a useful food ingredient for health promotion and chronic disease prevention.Abstract Background The Mediterranean diet is a healthy diet with positive scientific evidence of preventing chronic diseases. Bioactive components support the healthy properties of the Mediterranean diet. Antioxidants and fiber, two components of the Mediterranean diet, are key functional nutrients for healthy eating and nutrition. Wine grape pomace is a rich source of these dietary constituents and may be beneficial for human health. Our hypothesis was that the intake of red wine grape pomace flour (WGPF) prepared from red wine grapes (Cabernet Sauvignon variety) reduced the metabolic syndrome in humans. To evaluate the effect of WGPF on components of metabolic syndrome we design a 16-week longitudinal intervention study. Thirty-eight males, 30–65 years of age, with at least one component of metabolic syndrome, were randomly assigned to either the intervention group (n = 25) or the control group (n = 13). At lunch, the intervention group was given 20 g of WGPF per day, which contained 10 g of dietary fiber, 822 mg of polyphenols and an antioxidant capacity of 7258 ORAC units. Both groups were asked to maintain their regular eating habits and lifestyles. Clinical evaluation, anthropometric measurements and biochemical blood analyses were done at the beginning and the end of the study. Results WGPF intake significantly decreased systolic and diastolic blood pressure as well as fasting glucose levels. Plasma γ-tocopherol and δ-tocopherol increased and carbonyl group in plasma protein decreased in WGPT group, significantly. No significant effect was observed for waist circumference, HDL cholesterol, triglycerides, total antioxidant capacity and vitamin C in and between groups. The group-dependent magnitude of the differences between the baseline and final postprandial insulin values and γ-tocopherol concentrations was statistically significant. Conclusions The consumption of WGPF-rich in fiber and polyphenol antioxidants, as a food supplement in a regular diet improves blood pressure, glycaemia and postprandial insulin. In addition, increased antioxidant defenses and decreased oxidative protein damage indicating attenuation of oxidative stress. WGPF might be a useful food ingredient for health promotion and chronic disease prevention.Abstract Background The Mediterranean diet is a healthy diet with positive scientific evidence of preventing chronic diseases. Bioactive components support the healthy properties of the Mediterranean diet. Antioxidants and fiber, two components of the Mediterranean diet, are key functional nutrients for healthy eating and nutrition. Wine grape pomace is a rich source of these dietary constituents and may be beneficial for human health. Our hypothesis was that the intake of red wine grape pomace flour (WGPF) prepared from red wine grapes (Cabernet Sauvignon variety) reduced the metabolic syndrome in humans. To evaluate the effect of WGPF on components of metabolic syndrome we design a 16-week longitudinal intervention study. Thirty-eight males, 30–65 years of age, with at least one component of metabolic syndrome, were randomly assigned to either the intervention group (n = 25) or the control group (n = 13). At lunch, the intervention group was given 20 g of WGPF per day, which contained 10 g of dietary fiber, 822 mg of polyphenols and an antioxidant capacity of 7258 ORAC units. Both groups were asked to maintain their regular eating habits and lifestyles. Clinical evaluation, anthropometric measurements and biochemical blood analyses were done at the beginning and the end of the study. Results WGPF intake significantly decreased systolic and diastolic blood pressure as well as fasting glucose levels. Plasma γ-tocopherol and δ-tocopherol increased and carbonyl group in plasma protein decreased in WGPT group, significantly. No significant effect was observed for waist circumference, HDL cholesterol, triglycerides, total antioxidant capacity and vitamin C in and between groups. The group-dependent magnitude of the differences between the baseline and final postprandial insulin values and γ-tocopherol concentrations was statistically significant. Conclusions The consumption of WGPF-rich in fiber and polyphenol antioxidants, as a food supplement in a regular diet improves blood pressure, glycaemia and postprandial insulin. In addition, increased antioxidant defenses and decreased oxidative protein damage indicating attenuation of oxidative stress. WGPF might be a useful food ingredient for health promotion and chronic disease prevention.Abstract Background The Mediterranean diet is a healthy diet with positive scientific evidence of preventing chronic diseases. Bioactive components support the healthy properties of the Mediterranean diet. Antioxidants and fiber, two components of the Mediterranean diet, are key functional nutrients for healthy eating and nutrition. Wine grape pomace is a rich source of these dietary constituents and may be beneficial for human health. Our hypothesis was that the intake of red wine grape pomace flour (WGPF) prepared from red wine grapes (Cabernet Sauvignon variety) reduced the metabolic syndrome in humans. To evaluate the effect of WGPF on components of metabolic syndrome we design a 16-week longitudinal intervention study. Thirty-eight males, 30–65 years of age, with at least one component of metabolic syndrome, were randomly assigned to either the intervention group (n = 25) or the control group (n = 13). At lunch, the intervention group was given 20 g of WGPF per day, which contained 10 g of dietary fiber, 822 mg of polyphenols and an antioxidant capacity of 7258 ORAC units. Both groups were asked to maintain their regular eating habits and lifestyles. Clinical evaluation, anthropometric measurements and biochemical blood analyses were done at the beginning and the end of the study. Results WGPF intake significantly decreased systolic and diastolic blood pressure as well as fasting glucose levels. Plasma γ-tocopherol and δ-tocopherol increased and carbonyl group in plasma protein decreased in WGPT group, significantly. No significant effect was observed for waist circumference, HDL cholesterol, triglycerides, total antioxidant capacity and vitamin C in and between groups. The group-dependent magnitude of the differences between the baseline and final postprandial insulin values and γ-tocopherol concentrations was statistically significant. Conclusions The consumption of WGPF-rich in fiber and polyphenol antioxidants, as a food supplement in a regular diet improves blood pressure, glycaemia and postprandial insulin. In addition, increased antioxidant defenses and decreased oxidative protein damage indicating attenuation of oxidative stress. WGPF might be a useful food ingredient for health promotion and chronic disease prevention.
- ItemWine grape pomace flour in broiler diets effects growth and some meat characteristics(2020) Reyes, P.; Urquiaga Reus, Inés; Echeverría Errázuriz, Guadalupe; Duran, E.; Morales, M. S.; Valenzuela, C.