Browsing by Author "Trincado M, Patricio"

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    Guidelines of the Chilean Endocrinology Society for the correct clinical use of bone densitometry
    (SOC MEDICA SANTIAGO, 2018) Barberan M, Marcela; Campusano M, Claudia; Trincado M, Patricio; Oviedo G, Sofia; Brantes G, Sergio; Sapunar Z, Jorge; Canessa, Jose; Cid, Pia; Escobar, Freddy; Eugenin, Daniela; Florenzano, Pablo; Gajardo, Hector; Gonzalez, Gilberto; Illanes, Francisca; Jimenez, Beatriz; Martinez, Carolina; Miranda, Edith; Rivera, Sandra; Salman, Patricio; Trejo, Pamela; Velasco, Soledad
    Osteoporosis is a silent and frequent disease, which increases fracture risk Approximately half of women and one of five men over 50 years old will suffer an osteoporotic fracture throughout their lives. Dual-energy x-ray absorptiometry (DXA) allows a real bone mineral density (BMD) measurement in different parts of the skeleton and is considered the "gold standard" for quantifying osteoporosis with high accuracy and precision. The Board of the Chilean Society of Endocrinology and Diabetes (SOCHED) required from the Bone Disease Study Group to develop a consensus about the "Correct use of bone densitometry in clinical practice in Chilean population". Therefore, we elaborated 25 questions which addressed key aspects about the indications for a DXA scan, and the details of how to perform and report this test. Since some of the evidence obtained was of low quality or inconclusive, we decided to create a multidisciplinary group of national experts in osteoporosis to develop a consensus in this subject. The group consisted of 22 physicians including endocrinologists, gynecologists, geriatricians, radiologists, rheumatologists and nuclear medicine specialists. Using the Delphi methodology to analyze previously agreed questions, we elaborated statements that were evaluated by the experts who expressed their degree of agreement. The final report of this consensus was approved by the SOCHED board.
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    Vertebral fractures, osteoporosis and vitamin D levels in Chilean postmenopausal women
    (SOC MEDICA SANTIAGO, 2007) Rodriguez P, Jose A.; Valdivia C, Gonzalo; Trincado M, Patricio
    Background Approximately one-third of vertebral fractures can be clinically diagnosed. Aim: To study the. frequency of vertebral fractures in postmenopausal women. Patients and methods: We recruited 555 postmenopausal women from Santiago, Chile, aged 5584 years, who manifested interest in their bone health. All were healthy by self-declaration and by general clinical and laboratory tests and bad not taken any bone-active therapy. They all underwent a spine and femoral neck (FN) densitometry and a digital lateral spine X-ray from T4 to L4 was obtained. PTH, calcidiol, and other parameters of calcium metabolism were also measured. Results: Overall, 142 of 478 patients with a complete study (29.7%) had at least one vertebral fracture. The proportion of women with fractures increased with age. A T score below -2.5 in the spine and hip was found in 32% and 14% of women, respectively. The proportion of women with spinal opeoporosis doubled between ages 55-70 and remained constant afterwards. In contrast, at the femoral neck, this proportion increased progressively reaching 53.3% at age 80-85. However, 56% of patients with vertebral fractures did not have densitometric osteoporosis in any location. Calcidiol levels were 16.8 +/- 6.8 ng/mL. With a cutoff point of 17 ng/mL, 47.5 +/- 16 of the patients had hypovitaminosis D. There was no association between calcidiol levels and vertebral fractures or bone density at the spine or femoral neck. Patients with fractures differed from those without fractures in that they had significantly lower bone density at the spine and hip and were older (p <0.001). However they did not dyer in weight, body mass index, or calcidiol levels. Conclusions: Thirty percent of postmenopausal women in this series had a vertebral fractures. Osteoporosis and vitamin D deficiency were also common. Most vertebral fractures were observed in women without osteoporosis by densitometric criteria.