Browsing by Author "Tapia, R.A."
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- ItemMolecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione(2012) Lagos, C.F.; Araya-Secchi, R.; Thomas, P.; Pérez-Acle, T.; Tapia, R.A.; Salas Sanchez, Cristian Osvaldo
- ItemNatural and synthetic naphthoquinones active against Trypanosoma cruzi: An initial step towards new drugs for chagas disease(2011) Salas Sanchez, Cristian Osvaldo; Faúndez, M.; Morello, A.; Maya, J.D.; Tapia, R.A.
- ItemPromising 2,6,9-trisubstituted purine derivatives for anticancer compounds: Synthesis, 3D-QSAR, and preliminary biological assays(2020) Salas, C.O.; Zarate, A.M.; Kryštof, V.; Mella, J.; Faundez, M.; Brea, J.; Loza, M.I.; Brito, I.; Hendrychová, D.; Jorda, R.; Cabrera Caballero, Alan Raul; Tapia, R.A.; Espinosa-Bustos, C.
- ItemSynthesis of furanonaphthazarin derivatives(PERGAMON-ELSEVIER SCIENCE LTD, 1998) Tapia, R.A.; Garate, M.C.; Valderrama, J.A.; Jenkins, P.R.A three-step synthesis of the 58-dihydroxy-2-(1-methylethyl)naphtho[2,3-b]furan-4,9-dione (9) starting from 2-hydroxy-5,8-dimethoxy-1,4-naphthoquinone (4), is described. Further treatment of (9) with selenium dioxide in the presence of pyridine N-oxide as co-oxidant gave 2-(1-hydroxy-1-methylethyl)naphtho[2,3-b]furan-4,9-dione (10).