Browsing by Author "Silva, L."

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    Characterization of the phone-calls made to a poison center related to household and cosmetics products exposition in pediatrics
    (SOC CHILENA PEDIATRIA, 2019) Gonzalez, F.; Retamal, C.; Silva, L.; Cerda, P.; Medel, P.; Solari, S.; Mellado, R.; Rios, J. C.
    Introduction: Household cleaning products and cosmetics are necessary for daily life and widely used by the population. However, their use may not be risk-free, especially when they are not used or stored as recommended. It is important to characterize exposures, as this is useful for developing strategies to reduce morbidity, mortality, and health costs associated, especially in the child population. Objective: To describe reports associated with household cleaning products and cosmetics exposure in patients under the age of 12, reported to the Poison Information Center of the Catholic University of Chile (CITUC). Patients and Method: Descriptive cross-sectional study of phone calls to CITUC during 2016. The analyzed variables were age, sex, product, caller, caller and incident location, exposure circumstances, exposure route(s), symptoms, and severity from manual records and from the WHO's electronic record software 'INTOX Data Management System'. Results: 3,415 cases met the inclusion criteria. Children under the age of five represented 91% of the exposures, and 58.5% were male. 99.4% were accidental exposures, and 98.6% occurred at home. Family members (57%) and health personnel (42%) made the calls. 68.3% of the patients had no symptoms after exposure. The four products with the highest incidence were household bleach (27.6%), floor cleaners and polishers (13.1%), dish soap (7.9%), and perfume/cologne (5.8%). The main exposure route was by ingestion (89.4%). Conclusions: Household cleaning products and cosmetics are common causes of exposures especially in children under the age of five. Although these products have a low morbidity and mortality rate, it is important to educate the population to prevent possible poisonings in the child population.
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    Comprehensive comparison of models for spectral energy distributions from 0.1 μm to 1mm of nearby star-forming galaxies
    (2019) Hunt, L. K.; De Looze, I; Boquien, M.; Nikutta, R.; Rossi, A.; Bianchil, S.; Dale, D. A.; Granato, G. L.; Kennicutt, R. C.; Silva, L.; Ciesla, L.; Relano, M.; Viaene, S.; Brandl, B.; Calzetti, D.; Croxall, K., V; Draine, B. T.; Galametz, M.; Gordon, K. D.; Groves, B. A.; Helou, G.; Herrera-Camus, R.; Hinz, J. L.; Koda, J.; Salim, S.; Sandstrom, K. M.; Smith, J. D.; Wilson, C. D.; Zibetti, S.
    We have fit the far-ultraviolet (FUV) to sub-millimeter (850 mu m) spectral energy distributions (SEDs) of the 61 galaxies from the Key Insights on Nearby Galaxies: A Far-Infrared Survey with Herschel (KINGFISH). The fitting has been performed using three models: the Code for Investigating GALaxy Evolution (CIGALE), the GRAphite-SILicate approach (GRASIL), and the Multiwavelength Analysis of Galaxy PHYSical properties (MAGPHYS). We have analyzed the results of the three codes in terms of the SED shapes, and by comparing the derived quantities with simple "recipes" for stellar mass (M-star), star-formation rate (SFR), dust mass (M-dust), and monochromatic luminosities. Although the algorithms rely on different assumptions for star-formation history, dust attenuation and dust reprocessing, they all well approximate the observed SEDs and are in generally good agreement for the associated quantities. However, the three codes show very different behavior in the mid-infrared regime: in the 5-10 mu m region dominated by PAH emission, and also between 25 and 70 mu m where there are no observational constraints for the KINGFISH sample. We find that different algorithms give discordant SFR estimates for galaxies with low specific SFR, and that the standard recipes for calculating FUV absorption overestimate the extinction compared to the SED-fitting results. Results also suggest that assuming a "standard" constant stellar mass-to-light ratio overestimates Mstar relative to the SED fitting, and we provide new SED-based formulations for estimating Mstar from WISE W1 (3.4 mu m) luminosities and colors. From a principal component analysis of M-star, SFR, M-dust, and O/H, we reproduce previous scaling relations among Mstar, SFR, and O/H, and find that Mdust can be predicted to within similar to 0.3 dex using only M-star and SFR.
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    ENDOPLASMIC RETICULUM STRESS IN HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS FROM PRE-GESTATIONAL MATERNAL OBESITY
    (W B SAUNDERS CO LTD, 2017) Villalobos Labra, R.; Salsoso, R.; Subiabre, M.; Silva, L.; Farias Jofre, M.; Leiva, A.; Sobrevia, L.
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    Human supraphysiological gestational weight gain and fetoplacental vascular dysfunction
    (2015) Pardo, F.; Silva, L.; Sáez, T.; Salsoso Rodríguez, M. Rocío; Gutiérrez, J.; Sanhueza, C.; Leiva Mendoza, Andrea Alejandra; Sobrevía Luarte, Luis Alberto
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    Intracellular and extracellular pH dynamics in the human placenta from diabetes mellitus
    (2016) Araos, J.; Silva, L.; Salsoso Rodríguez, M. Rocío; Saez, T.; Barros Lamus, Eric Raúl; Toledo, F.; Gutierrez, J.; Pardo, F.; Leiva Mendoza, Andrea Alejandra; Sanhueza C.; Sobrevía Luarte, Luis Alberto
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    Pre-pregnancy maternal obesity associates with endoplasmic reticulum stress in human umbilical vein endothelium
    (2018) Villalobos Labra, Roberto Esteban; Saez, P.; Subiabre Morales, Mario Enrique; Silva, L.; Toledo, F.; Westermeier, F.; Pardo, F.; Farías Jofré, Marcelo Enrique; Sobrevía Luarte, Luis Alberto