Browsing by Author "Schuenemann, Holger"

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    A guide for health professionals to interpret and use recommendations in guidelines developed with the GRADE approach
    (2016) Neumann, Ignacio; Santesso, Nancy; Akl, Elie A.; Rind, David M.; Vandvik, Per Olav; Alonso-Coello, Pablo; Agoritsas, Thomas; Mustafa, Reem A.; Alexander, Paul Elias; Schuenemann, Holger; Guyatt, Gordon H.
    An increasing number of organizations worldwide are using new and improved standards for developing trustworthy clinical guidelines. One of such approaches, developed by the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) working group, offers systematic and transparent guidance in moving from evidence to recommendations. The GRADE strategy concentrates on four factors: the balance between benefits and harms, the certainty of the evidence, values and preferences, and resource considerations. However, it also considers issues around feasibility, equity, and acceptability of recommendations. GRADE distinguishes two types of recommendations: strong and weak. Strong recommendations reflect a clear preference for one alternative and should apply to all or almost all patients, obviating the need for a careful review of the evidence with each patient. Weak recommendations are appropriate when there is a close balance between desirable and undesirable consequences of alternative management strategies, uncertainty regarding the effects of the alternatives, uncertainty or variability in patients' values and preferences, or questionable cost-effectiveness. Weak recommendations usually require accessing the underlying evidence and a shared decision-making approach. Clinicians using GRADE recommendations should understand the meaning of the strength of the recommendation, be able to critically appraise the recommendation, and apply trustworthy recommendations according to their strength. (C) 2016 Elsevier Inc. All rights reserved.
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    ASH, ABHH, ACHO, Grupo CAHT, Grupo CLAHT, SAH, SBHH, SHU, SOCHIHEM, SOMETH, Sociedad Panamena de Hematologia, SPH, and SVH 2021 guidelines for management of venous thromboembolism in Latin America
    (ELSEVIER, 2021) Neumann, Ignacio; Izcovich, Ariel; Aguilar, Ricardo; Leon Basantes, Guillermo; Casais, Patricia; Colorio, Cecilia C.; Guillermo Esposito, Maria Cecilia; Garcia Lazaro, Pedro P.; Meillon Garcia, Luis A.; Pereira, Jaime; Rezende, Suely Meireles; Carlos Serrano, Juan; Tejerina Valle, Mario L.; Vera, Felipe; Karzulovic, Lorena; Rada, Gabriel; Schuenemann, Holger
    Background: Venous thromboembolism (VTE) is a common disease in Latin American settings. Implementing international guidelines in Latin American settings requires additional considerations.
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    Low Anonymous Voting Compliance With the Novel Policy for Managing Conflicts of Interest Implemented in the 9th Version of the American College of Chest Physicians Antithrombotic Guidelines
    (2013) Neumann, Ignacio; Akl, Elie A.; Valdes, Macarena; Bravo, Stephanie; Araos, Silvana; Kairouz, Victor; Schuenemann, Holger; Guyatt, Gordon H.
    Background: The executive committee of the Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (AT9) developed a strategy to limit the impact of conflict of interest (COI) on recommendations. This policy excluded conflicted panelists from voting on recommendations with which they had conflicts. The objective of the study is to explore the compliance of the attendees of the AT9 final conference.
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    Methodology for adaptation of the ASH Guidelines for Management of Venous Thromboembolism for the Latin American context
    (2021) Neumann, Ignacio; Izcovich, Ariel; Alexander, Kendall E.; Castano, Jenny; Plovnick, Robert; Kunkle, Robert; Zhang, Yuan; Aguilar, Ricardo; Leon Basantes, Guillermo; Casais, Patricia; Colorio, Cecilia C.; Guillermo Esposito, Maria Cecilia; Garcia Lazaro, Pedro P.; Pereira, Jaime; Meillon-Garcia, Luis A.; Rezende, Suely Meireles; Carlos Serrano, Juan; Tejerina Valle, Mario L.; Schuenemann, Holger
    Background: From 2017 to 2020, the American Society of Hematology (ASH) collaborated with 12 hematology societies in Latin America to adapt the ASH guidelines on venous thromboembolism (VTE).