Browsing by Author "Salas Sanchez, Cristian Osvaldo"
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- ItemA New Smoothened Antagonist Bearing the Purine Scaffold Shows Antitumour Activity In Vitro and In Vivo(2021) Ana María Zárate; Christian Espinosa-Bustos; Simon Guerrero; Angélica Fierro; Felipe Oyarzún-Ampuero; Andrew Quest; LUCIA DI MARCOTULLIO; Elena Loricchio; Miriam Caimano; Andrea CALCATERRA; Matias Eduardo González Quiroz; Adam Aguirre; Jaime Meléndez; Salas Sanchez, Cristian Osvaldo
- ItemConvergent synthesis, drug target prediction, and docking studies of new 2,6,9-trisubstituted purine derivatives(2021) Villegas, A.; Satheeshkumar, R.; Ballesteros-Casallas, A.; Paulino, M.; Castro, A.; Espinosa-Bustos, C.; Salas Sanchez, Cristian Osvaldo
- ItemCytotoxic Activity, Topoisomerase I Inhibition and In Silico Studies of New Sesquiterpene-aryl Ester Derivatives of (-) Drimenol(2023) Ileana Araque; Javiera Ramírez; Rut Vergara; jaime mella; Pablo Aránguiz; Luis Espinoza; Vera, W.; ivan montenegro; Salas Sanchez, Cristian Osvaldo; Joan Villena; Mauricio A. Cuellar
- ItemDesign, Synthesis, In Silico Studies and Inhibitory Activity towards Bcr-Abl, BTK and FLT3-ITD of New 2,6,9-Trisubstituted Purine Derivatives as Potential Agents for the Treatment of Leukaemia(2022) Jeanluc Bertrand; Hana Dostálová; Vladimir Krystof; Radek Jorda; Thalía Delgado; Alejandro Castro-Alvarez; jaime mella; David Cabezas; Mario Faúndez; Christian Espinosa-Bustos; Salas Sanchez, Cristian Osvaldo
- ItemIntramolecular diels-alder furan-mediated synthesis of 8-Aryl-3,4-di- hydroisoquinolin-1(2 H)-ones, convenient precursors of indeno[1,2,3- ij ]isoquinolines(2013) Treus, M.; Harwood, L.; Estévez, J.; Salas Sanchez, Cristian Osvaldo; Drew, M.B.; Estévez, R.
- ItemKey proteins in the polyamine-trypanothione pathway as drug targets against Trypanosoma cruzi(2014) Maya, J.D.; Salas Sanchez, Cristian Osvaldo; Aguilera-Venegas, B.; Diaz, M.V.; López-Muñoz, R.
- ItemMolecular modeling of Trypanosoma cruzi glutamate cysteine ligase and investigation of its interactions with glutathione(2012) Lagos, C.F.; Araya-Secchi, R.; Thomas, P.; Pérez-Acle, T.; Tapia, R.A.; Salas Sanchez, Cristian Osvaldo
- ItemNatural and synthetic naphthoquinones active against Trypanosoma cruzi: An initial step towards new drugs for chagas disease(2011) Salas Sanchez, Cristian Osvaldo; Faúndez, M.; Morello, A.; Maya, J.D.; Tapia, R.A.
- ItemNew Amino Naphthoquinone Derivatives as Anti-Trypanosoma cruzi Agents Targeting Trypanothione Reductase(2022) Christian Espinosa-Bustos; Mariana Ortiz Pérez; Alonzo Gonzalez-Gonzalez; Ana María Zárate; Gildardo Rivera; Javier A. Belmont-Díaz; Emma Saavedra; Mauricio A. Cuellar; Karina Vázquez; Salas Sanchez, Cristian Osvaldo
- ItemState of the art of Smo antagonists for cancer therapy: Advances in the target receptor and new ligand structures(2019) Espinosa-Bustos, C.; Mella, J.; Soto-Delgado, J.; Salas Sanchez, Cristian Osvaldo
- ItemSubstituted Purines as High-Affinity Histamine H3 Receptor Ligands(2022) Christian Espinosa-Bustos; Luisa Leitzbach; Tito Añazco; María J. Silva; Andrea del Campo; Alejandro Castro-Alvarez; Holger STARK; Salas Sanchez, Cristian Osvaldo
- ItemTrypanothione reductase: A target for the development of anti-Trypanosoma cruzi drugs(2017) Vázquez, K.; Paulino, M.; Salas Sanchez, Cristian Osvaldo; Zarate-Ramos, J.J.; Vera, B.; Rivera, G.
- ItemUnveiling interactions between DNA and cytotoxic 2-arylpiperidinyl-1,4-naphthoquinone derivatives: A combined electrochemical and computational study(2020) Espinosa-Bustos, C.; Canales, C.; Ramírez, G.; Jaque, P.; Salas Sanchez, Cristian Osvaldo