Browsing by Author "Rada G., Gabriel"

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    A comparative evaluation of PDQ-Evidence
    (2018) Johansen, Marit; Rada G., Gabriel; Rosenbaum, Sarah; Paulsen, Elizabeth; Motaze, Nkengafac V.; Opiyo, Newton; Wiysonge, Charles S.; Ding, Yunpeng; Mukinda, Fidele K.; Oxman, Andrew D.
    Abstract Background A strategy for minimising the time and obstacles to accessing systematic reviews of health system evidence is to collect them in a freely available database and make them easy to find through a simple ‘Google-style’ search interface. PDQ-Evidence was developed in this way. The objective of this study was to compare PDQ-Evidence to six other databases, namely Cochrane Library, EVIPNet VHL, Google Scholar, Health Systems Evidence, PubMed and Trip. Methods We recruited healthcare policy-makers, managers and health researchers in low-, middle- and high-income countries. Participants selected one of six pre-determined questions. They searched for a systematic review that addressed the chosen question and one question of their own in PDQ-Evidence and in two of the other six databases which they would normally have searched. We randomly allocated participants to search PDQ-Evidence first or to search the two other databases first. The primary outcomes were whether a systematic review was found and the time taken to find it. Secondary outcomes were perceived ease of use and perceived time spent searching. We asked open-ended questions about PDQ-Evidence, including likes, dislikes, challenges and suggestions for improvements. Results A total of 89 people from 21 countries completed the study; 83 were included in the primary analyses and 6 were excluded because of data errors that could not be corrected. Most participants chose PubMed and Cochrane Library as the other two databases. Participants were more likely to find a systematic review using PDQ-Evidence than using Cochrane Library or PubMed for the pre-defined questions. For their own questions, this difference was not found. Overall, it took slightly less time to find a systematic review using PDQ-Evidence. Participants perceived that it took less time, and most participants perceived PDQ-Evidence to be slightly easier to use than the two other databases. However, there were conflicting views about the design of PDQ-Evidence. Conclusions PDQ-Evidence is at least as efficient as other databases for finding health system evidence. However, using PDQ-Evidence is not intuitive for some people. Trial registration The trial was prospectively registered in the ISRCTN registry 17 April 2015. Registration number: ISRCTN12742235 .Abstract Background A strategy for minimising the time and obstacles to accessing systematic reviews of health system evidence is to collect them in a freely available database and make them easy to find through a simple ‘Google-style’ search interface. PDQ-Evidence was developed in this way. The objective of this study was to compare PDQ-Evidence to six other databases, namely Cochrane Library, EVIPNet VHL, Google Scholar, Health Systems Evidence, PubMed and Trip. Methods We recruited healthcare policy-makers, managers and health researchers in low-, middle- and high-income countries. Participants selected one of six pre-determined questions. They searched for a systematic review that addressed the chosen question and one question of their own in PDQ-Evidence and in two of the other six databases which they would normally have searched. We randomly allocated participants to search PDQ-Evidence first or to search the two other databases first. The primary outcomes were whether a systematic review was found and the time taken to find it. Secondary outcomes were perceived ease of use and perceived time spent searching. We asked open-ended questions about PDQ-Evidence, including likes, dislikes, challenges and suggestions for improvements. Results A total of 89 people from 21 countries completed the study; 83 were included in the primary analyses and 6 were excluded because of data errors that could not be corrected. Most participants chose PubMed and Cochrane Library as the other two databases. Participants were more likely to find a systematic review using PDQ-Evidence than using Cochrane Library or PubMed for the pre-defined questions. For their own questions, this difference was not found. Overall, it took slightly less time to find a systematic review using PDQ-Evidence. Participants perceived that it took less time, and most participants perceived PDQ-Evidence to be slightly easier to use than the two other databases. However, there were conflicting views about the design of PDQ-Evidence. Conclusions PDQ-Evidence is at least as efficient as other databases for finding health system evidence. However, using PDQ-Evidence is not intuitive for some people. Trial registration The trial was prospectively registered in the ISRCTN registry 17 April 2015. Registration number: ISRCTN12742235 .Abstract Background A strategy for minimising the time and obstacles to accessing systematic reviews of health system evidence is to collect them in a freely available database and make them easy to find through a simple ‘Google-style’ search interface. PDQ-Evidence was developed in this way. The objective of this study was to compare PDQ-Evidence to six other databases, namely Cochrane Library, EVIPNet VHL, Google Scholar, Health Systems Evidence, PubMed and Trip. Methods We recruited healthcare policy-makers, managers and health researchers in low-, middle- and high-income countries. Participants selected one of six pre-determined questions. They searched for a systematic review that addressed the chosen question and one question of their own in PDQ-Evidence and in two of the other six databases which they would normally have searched. We randomly allocated participants to search PDQ-Evidence first or to search the two other databases first. The primary outcomes were whether a systematic review was found and the time taken to find it. Secondary outcomes were perceived ease of use and perceived time spent searching. We asked open-ended questions about PDQ-Evidence, including likes, dislikes, challenges and suggestions for improvements. Results A total of 89 people from 21 countries completed the study; 83 were included in the primary analyses and 6 were excluded because of data errors that could not be corrected. Most participants chose PubMed and Cochrane Library as the other two databases. Participants were more likely to find a systematic review using PDQ-Evidence than using Cochrane Library or PubMed for the pre-defined questions. For their own questions, this difference was not found. Overall, it took slightly less time to find a systematic review using PDQ-Evidence. Participants perceived that it took less time, and most participants perceived PDQ-Evidence to be slightly easier to use than the two other databases. However, there were conflicting views about the design of PDQ-Evidence. Conclusions PDQ-Evidence is at least as efficient as other databases for finding health system evidence. However, using PDQ-Evidence is not intuitive for some people. Trial registration The trial was prospectively registered in the ISRCTN registry 17 April 2015. Registration number: ISRCTN12742235 .
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    ¿Aceleran los aminoácidos de cadena ramificada la recuperación de la encefalopatía hepática en pacientes con cirrosis?
    (2016) Vergara, Maximiliano; Castro Gutiérrez, Victoria; Rada G., Gabriel
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    Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death
    (2015) Claro, J. C.; Candia Balboa, Roberto; Rada G., Gabriel; Baraona Reyes, Fernando Exequiel; Larrondo Castro, Luis Fernando; Letelier Saavedra, Luz María; Claro, J. C.; Candia Balboa, Roberto; Rada G., Gabriel; Baraona, F.; Larrondo Castro, Luis Fernando; Letelier Saavedra, Luz María
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    Are cannabinoids effective for fibromyalgia?
    (2018) Rocco, Matías; Rada G., Gabriel
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    Are oral estrogens effective in preventing urinary tract infection in postmenopausal women?
    (2020) Castro, V.; Canales, J. P.; Rada G., Gabriel
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    Are probiotics effective in preventing urinary tract infection?
    (2018) Canales, Juan; Rada G., Gabriel
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    Arteterapia, ¿es efectiva en la esquizofrenia?
    (2017) Ruiz, M.; Aceituno Farías, David; Rada G., Gabriel
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    Bautismo y sociedad.
    (1974) Rada G., Gabriel
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    Bipolar or monopolar transurethral resection for benign prostatic hyperplasia?
    (2018) Inzunza, Gabriel; Rada G., Gabriel; Majerson Grinberg, Alejandro
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    ¿Cabergolina o bromocriptina para el prolactinoma?
    (2016) Triantafilo, N.; Castro Gutiérrez, V.; Rada G., Gabriel
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    Cánula nasal de alto flujo en adultos con enfermedades respiratorias crónicas durante el ejercicio físico: protocolo de revisión sistemática y metaanálisis
    (2022) Moya Gallardo, Eduardo Sebastián; Fajardo Gutiérrez, Jennifer; Acevedo Encalada, Karol Stefanie; Verdugo Paiva, Francisca; Bravo Jeria, Rocío; Rada G., Gabriel; Contreras Briceño, Felipe; Espinosa Ramírez, Maximiliano
    Introducción. El entrenamiento físico puede mejorar la capacidad de ejercicio, la disnea y la calidad de vida (CV) en pacientes con enfermedades respiratorias crónicas (ERC). En este contexto, el uso de oxígeno suplementario a través de una cánula nasal de alto flujo (CNAF) podría ser un dispositivo que permita tolerar mayores niveles de actividad con menos síntomas de esfuerzo físico, optimizando en última instancia la capacidad de ejercicio y la CV. Objetivo. Este protocolo pretende conducir una revisión sistemática para evaluar el efecto terapéutico de la CNAF durante el ejercicio físico en pacientes con ERC. Fuente de búsqueda. Se realizarán búsquedas en el Registro Cochrane Central de Ensayos Controlados (CENTRAL), PUBMED, Embase, Lilacs, Physiotherapy Evidence Database (PEDro), International Clinical Trials Registry Platform (ICTRP), ClinicalTrials.gov y literatura gris. Criterios de elegibilidad. Examinaremos los ECA de acuerdo con los criterios de elegibilidad para su inclusión en nuestra revisión. Dos revisores examinarán de forma independiente cada estudio para la elegibilidad, la extracción de datos y la evaluación del riesgo de sesgo. Se combinarán los resultados mediante un metanálisis y se aplicará el sistema GRADE para evaluar la certeza de las pruebas para cada resultado. La medida de resultado primaria será la capacidad de ejercicio, y las medidas de resultado secundarias serán la calidad de vida, la disnea, la funcionalidad, la comodidad, las complicaciones y adherencia. Se realizarán metaanálisis para determinar la diferencia de medias (DM) o la DM estandarizada para los datos continuos y la razón de riesgo para los datos dicotómicos. Se realizarán análisis de subgrupos según los tipos y la gravedad de la enfermedad, las condiciones de ejercicio físico y el estado de los dispositivos de oxigenoterapia. Ética y difusión. Como los investigadores no accederán a información que pueda conducir a la identificación de un participante individual, no fue necesario a obtener aprobación ética.
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    Childhood vaccination communication outcomes unpacked and organized in a taxonomy to facilitate core outcome establishment
    (2017) Kaufman, Jessica; Ryan, Rebecca; Glenton, Claire; Lewin, Simon; Bosch-Capblanch, Xavier; Cartier, Yuri; Cliff, Julie; Oyo-Ita, Angela; Ames, Heather; Rada G., Gabriel; Muloliwa, Artur Manuel; Oku, Afiong; Hill, Sophie
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    ¿Cirugía laparoscópica o abierta para el tratamiento del quiste hidatídico?
    (2016) Ahumada, Vanessa; Moraga, Felipe; Rada G., Gabriel
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    Communication strategies to promote the uptake of childhood vaccination in Nigeria : a systematic map
    (2016) Oku, A.; Oyo-Ita, A.; Glenton, C.; Fretheim, A.; Ames, H.; Muloliwa, A.; Rada G., Gabriel; Kaufman, J.; Hill, S.; Cliff, J.; Cartier, Y.; Bosch-Capblanch, X.; Lewin, S.
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    Composición corporal de neonatos con alteraciones en el crecimiento fetal
    (1999) Mardones, Francisco; Bastías, Gabriel; Farías Jofré, Marcelo; Dinamarca V., Raúl; Olavarría FM., Fernando; Rada G., Gabriel; Rojas González, Álvaro Miguel; Rojas González, Pamela
    Con el objetivo de estudiar la asociación entre la composición corporal en recién nacidos con el peso al nacer y las alteraciones del crecimiento fetal, se estimó las masas magra y grasa de 224 recién nacidos de familias de bajos ingresos en Santiago de Chile, utilizando el método antropométrico de Dauncey. En el total de estos niños sanos de término la proporción de masa grasa fue 16,5%. Hubo una fuerte y significativa asociación positiva del peso al nacer con la masa magra (r2 = 88,9%) y con la masa grasa (r2= 58,2%). Aunque la masa grasa constituyó sólo 16,5% del peso al nacer, explicó una gran proporción de su varianza (58,2%). En los neonatos con retardo del crecimiento fetal o con bajo índice ponderal hubo una composición corporal particular. Esos recién nacidos tuvieron valores absolutos inferiores tanto de la masa grasa como de la masa magra, pero sólo la masa grasa fue proporcionalmente menor que en los niños normales o con sobrepaso. El déficit nutricional de estos niños está asociado con un mayor riesgo de afecciones perinatales, por lo que debiera ser prevenido con una adecuada alimentación de la madre durante el embarazo. Los resultados obtenidos, similares a los de estudios previos en países desarrollados, sugieren que la estimación de la composición corporal podría ser útil para evaluar el crecimiento fetal al momento del nacimiento.
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    ¿Constituyen los cannabinoides una alternativa terapéutica en anorexia nerviosa?
    (2017) Contreras, Tania; Bravo Soto, Gonzalo A.; Rada G., Gabriel
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    Correction to: Users’ experiences with an interactive Evidence to Decision (iEtD) framework: a qualitative analysis
    (2021) Meneses-Echavez, José Francisco; Rosenbaum, Sarah; Rada G., Gabriel; Flottorp, Signe; Moberg, Jenny; Alonso Coello, Pablo; Meneses-Echavez, José Francisco; Rosenbaum, Sarah; Rada G., Gabriel; Flottorp, Signe; Moberg, Jenny; Alonso Coello, Pablo
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    COVID-19 transmission during swimming-related activities : a rapid systematic review
    (2021) Yaacoub, Sally; Khabsa, Joanne; El-Khoury, Rayane; El-Harakeh, Amena; Lotfi, Tamara; Saad, Zahra; Itani, Zeina; Khamis, Assem M.; Verdugo-Paiva, Francisca; Rada G., Gabriel
    Background: There are uncertainties about mitigating strategies for swimming-related activities in the context of the COVID-19 pandemic. There is an opportunity to learn from the experience of previous re-openings to better plan the future one. Our objectives are to systematically review the evidence on (1) the association between engaging in swimming-related activities and COVID-19 transmission; and (2) the efects of strategies for preventing COVID-19 transmission during swimming-related activities. Methods: We conducted a rapid systematic review. We searched in the L-OVE (Living OVerview of Evidence) plat‑form for COVID-19. The searches covered the period from the inception date of each database until April 19, 2021. We included non-randomized studies for the review on association of COVID-19 transmission and swimming-related activities. We included guidance documents reporting on the strategies for prevention of COVID-19 transmission during swimming-related activities. We also included studies on the efcacy and safety of the strategies. Teams of two reviewers independently assessed article eligibility. For the guidance documents, a single reviewer assessed the eligibility and a second reviewer verifed the judgement. Teams of two reviewers extracted data independently. We summarized the fndings of included studies narratively. We synthesized information from guidance documents according to the identifed topics and subtopics, and presented them in tabular and narrative formats. Results: We identifed three studies providing very low certainty evidence for the association between engaging in swimming-related activities and COVID-19 transmission. The analysis of 50 eligible guidance documents identifed 11 topics: ensuring social distancing, ensuring personal hygiene, using personal protective equipment, eating and drinking, maintaining the pool, managing frequently touched surfaces, ventilation of indoor spaces, screening and management of sickness, delivering frst aid, raising awareness, and vaccination. One study assessing the efcacy of strategies to prevent COVID-19 transmission did not fnd an association between compliance with precautionary restrictions and COVID-19 transmission. Conclusions: There are major gaps in the research evidence of relevance to swimming-related activities in the context of the COVID-19 pandemic. However, the synthesis of the identifed strategies from guidance documents can inform public health management strategies for swimming-related activities, particularly in future re-opening plans.
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    Deambulación precoz versus reposo para pacientes con trombosis venosa profunda
    (2016) Izcovich, Ariel; Popoff, Federico; Rada G., Gabriel
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