Browsing by Author "Onetto Flores, María Teresa"

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    Hypoglycemia and glycemic variability of people with type 1 diabetes with lower and higher physical activity loads in free-living conditions using continuous subcutaneous insulin infusion with predictive low-glucose suspend system
    (2023) Montt Blanchard, Denise; Sánchez, Raimundo; Dubois Camacho, Karen; Leppe, Jaime; Onetto Flores, María Teresa
    Introduction Maintaining glycemic control during and after physical activity (PA) is a major challenge in type 1 diabetes (T1D). This study compared the glycemic variability and exercise-related diabetic management strategies of adults with T1D achieving higher and lower PA loads in nighttime-daytime and active- sedentary behavior hours in free-living conditions., Research design and methods Active adults (n=28) with T1D (ages: 35 +/- 10 years; diabetes duration: 21 +/- 11 years; body mass index: 24.8 +/- 3.4 kg/m(2); glycated hemoglobin A1c: 6.9 +/- 0.6%) on continuous subcutaneous insulin delivery system with predictive low glucose suspend system and glucose monitoring, performed different types, duration and intensity of PA under free-living conditions, tracked by accelerometer over 14 days. Participants were equally divided into lower load (LL) and higher load (HL) by median of daily counts per minute (61122). Glycemic variability was studied monitoring predefined time in glycemic ranges (time in range (TIR), time above range (TAR) and time below range (TBR)), coefficient of variation (CV) and mean amplitude of glycemic excursions (MAGE). Parameters were studied in defined hours timeframes (nighttime-daytime and active-sedentary behavior). Self-reported diabetes management strategies were analysed during and post-PA., Results Higher glycemic variability (CV) was observed in sedentary hours compared with active hours in the LL group (p <= 0.05). HL group showed an increment in glycemic variability (MAGE) during nighttime versus daytime (p <= 0.05). There were no differences in TIR and TAR across all timeframes between HL and LL groups. The HL group had significantly more TBR during night hours than the LL group (p <= 0.05). Both groups showed TBR above recommended values. All participants used fewer post-PA management strategies than during PA (p <= 0.05)., Conclusion Active people with T1D are able to maintain glycemic variability, TIR and TAR within recommended values regardless of PA loads. However, the high prevalence of TBR and the less use of post-PA management strategies highlights the potential need to increase awareness on actions to avoid glycemic excursions and hypoglycemia after exercise completion.
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    Individualized visual narratives: type 1 diabetes management strategies among three runners in the London Marathon
    (2023) Montt Blanchard, Denise; Onetto Flores, María Teresa; Sánchez, Raimundo
    This study investigates the diabetes management strategies of three high-level athletes with Type 1 Diabetes (t1D) during the 43rd London Marathon. The athletes’ strategies, which included insulin dose adjustments, carbohydrate intake, and monitoring techniques, were analyzed using a collaborative autoethnographic approach and data from medical and running devices. The athletes, two males and one female, used various technologies such as Supersapiens, Freestyle Libre, and the Medtronic Minimed 780g insulin pump to manage their diabetes during the marathon. Despite individual challenges, all three athletes successfully completed the marathon. The study presents the strategies, glycemic data, and major highlights using visual narratives, providing valuable insights into the experiences of athletes with t1D during endurance events. These narratives effectively communicate the challenges faced by athletes with t1D and can help optimize diabetes management during endurance events.
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    Lower versus standard sucrose dose for treating hypoglycemia in patients with type 1 diabetes mellitus in therapy with predictive low glucose suspend (PLGS) augmented insulin pumps: A randomized crossover trial in Santiago, Chile
    (ELSEVIER SCI LTD, 2021) Grassi Corrales, Bruno; Onetto Flores, María Teresa; Zapata Olivares, Yazmin Alejandra; Jofre Mendoza, Paulina Eugenia; Echeverria Errazuriz, Guadalupe
    Background and aims: Recommended hypoglycemia treatment in adults with T1D consists of 15 g of rapid absorption carbohydrates. We aimed to evaluate the response to fewer carbohydrates for treating hypoglycemia in patients with T1D on insulin pumps with predictive suspension technology (PLGS).