Browsing by Author "Navarrete, Cristian"

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    Efficacy of topical photodynamic therapy for keratoacanthomas: A case-series of four patients
    (MEDKNOW PUBLICATIONS & MEDIA PVT LTD, 2012) Farias, Maria M.; Hasson, Ariel; Navarrete, Cristian; Nicklas, Claudia; Garcia Huidobro, Isidora; Gonzalez, Sergio
    Topical photodynamic therapy (PDT) is an excellent treatment option for various non-melanoma skin cancers and precancerous lesions, including actinic keratosis, Bowen's disease, and basal cell carcinoma. The clinical use of PDT includes a broad range of neoplastic, inflammatory, and infectious skin diseases. There is also anecdotal evidence suggesting the efficacy of PDT for the treatment of keratoacanthomas (KA). We report a case-series of four patients with solitary KA confirmed by histology, treated with topical PDT with methylaminolevulinic acid (MAL) cream. After three sessions of PDT, the lesions completely disappeared. There was no evidence of recurrence and excellent cosmetic outcome was achieved after three years of follow-up. Topical photodynamic therapy with MAL can be a therapeutic alternative for KA with good clinical and cosmetic outcomes.
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    Periorbital Syringoma Treated With Radiofrequency and Carbon Dioxide (CO2) Laser in 5 Patients
    (JOURNAL OF DRUGS IN DERMATOLOGY, 2012) Hasson, Ariel; Magdalena Farias, Maria; Nicklas, Claudia; Navarrete, Cristian
    Syringomas are common benign eccrine ductal adnexial tumors, commonly found in periorbital area. Periorbital syringomas are aesthetically disturbing difficult to treat. Many treatment modalities are described in the literature, including topical and surgical methods, with potential problems such as postinflammatory hyper- and hypopigmentation, low efficacy, or scar formation. We present 5 patients with syringoma treated with the combination of radiofrequency ablation and carbon dioxide (CO2) lasers. Using low-energy parameters on the CO2 laser, and low energy on the radiofrequency, we could complement both treatments maximizing the destruction of the tumors and minimizing the adverse effects in only two sessions. This is a relatively easy, safe, and less painful treatment, with good cosmetic results on periorbital syringomas.