Browsing by Author "Muñoz Schuffenegger, Pablo"
Now showing 1 - 8 of 8
Results Per Page
Sort Options
- ItemCarcinoma escamoso de la conjuntiva con compromiso extraocular : reporte de caso y revision de la literatura(2016) Goñi Espíldora, Ignacio; Jans, Jaime; Petric Guajardo, Militza; Manzor Véliz, Manuel; Flores Pérez, Juan Carlos; Varas Marchant, Gonzalo; Muñoz Schuffenegger, Pablo; Zoroquiain Vélez, José Pablo
- ItemCollective Share Quotas and the Role of Fishermen's Organizations in Ex-Vessel Price Determination(2019) Peña Torres, Julio Alejandro; Dresdner, Jorge; Muñoz Schuffenegger, Pablo; Luzardo, Iván
- ItemDiagnóstico precoz de cáncer gástrico. Propuesta de detección y seguimiento de lesiones premalignas gástricas : protocolo ACHED(2014) Rollán, Antonio; Cortés, Pablo; Calvo, Oscar; Araya, Raúl; Bufadel, María Ester; González Donoso, Robinson; Heredia, Carolina; Muñoz Schuffenegger, Pablo; Squella, Fredy; Parra-Blanco, A.
- ItemIleostomía en asa derivativa y lavado colónico intraoperatorio como alternativa de tratamiento en un caso de colitis grave por Clostridium difficile(2015) Muñoz Schuffenegger, Pablo; Castillo, Richard; Villalón, Constanza; Zúñiga, José Miguel; Manterola, Carla; Molina, María Elena; Bellolio R., Felipe; Urrejola Schmied, Gonzalo Ignacio
- ItemMultimodal assessment of acute cardiac toxicity induced by thoracic radiotherapy in cancer patients : study protocol(2021) Merino Lara, Tomas Rodrigo; Pinto, Mauricio P.; Orellana Vargas, María Paz; Martínez, Gonzalo; Andía Kohnenkampf, Marcelo Edgardo; Muñoz Schuffenegger, Pablo; Acevedo Claros, Francisco Nicolás; Gabrielli, Luigi; Sánchez Rojel, César Giovanni; Pereira, JaimeBackground : Today, cancer ranks as one of the leading causes of death. Despite the large number of novel available therapies, radiotherapy (RT) remains as the most effective non-surgical method to cure cancer patients. In fact, approximately 50% of all cancer patients receive some type of RT and among these 60% receive RT-treatment with a curative intent. However, as occurs with any other oncological therapy, RT treated patients may experience toxicity side effects that range from moderate to severe. Among these, cardiotoxicity represents a significant threat for premature death. Current methods evaluate cardiotoxic damage based on volumetric changes in the Left Ventricle Ejected Fraction (LVEF). Indeed, a 10% drop in LVEF is commonly used as indicator of cardiotoxicity. More recently, a number of novel techniques have been developed that significantly improve specificity and sensitivity of heart’s volumetric changes and early detection of cardiotoxicity even in asymptomatic patients. Among these, the Strain by Speckle Tracking (SST) is a technique based on echocardiographic analysis that accurately evaluates myocardial deformation during the cardiac cycle (ventricular and atrial function). Studies also suggest that Magnetic Resonance Imaging (MRI) is a high-resolution technique that enables a better visualization of acute cardiac damage. Methodology: This protocol will evaluate changes in SST and MRI in cancer patients that received thoracic RT. Concomitantly, we will assess changes in serum biomarkers of cardiac damage in these patients, including: high-sensitivity cardiac Troponin-T (hscTnT), N-Terminal pro-Brain Natriuretic Peptide (NTproBNP) and Circulating Endothelial Cells (CECs), a marker of endothelial dysfunction and vascular damage. Discussion: The presented protocol is to our knowledge the first to prospectively and with a multimodal approach, study serological and image biomarkers off early cardiac damage due to radiotherapy. With a practical clinical approach we will seek early changes that could potentially be in the future be linked to clinical mayor events with consequences for cancer survivors.
- ItemQuantifying Health Utilities in Patients Undergoing Stereotactic Body Radiation Treatment for Liver Metastases for Use in Future Economic Evaluations(2017) Warren, B.; Muñoz Schuffenegger, Pablo; Chan, K. K. W.; Chu, W.; Helou, J.; Erler, D.; Chung, H.
- ItemRadiation recall dermatitis: Report of two cases(2013) Acevedo Claros, Francisco Nicolás; Arriagada, Paula; Ibáñez, Carolina; Ortega Mogilevich, Claudia Beatriz; Muñoz Schuffenegger, Pablo; Borghero Ríos, Yerko Orestes; Bustos Carrasco, Marisa Orietta; Sánchez Rojel, César Giovanni
- ItemThe business management of the Chilean salmon farming industry(2015) Little Orellana, Cedric; Felzensztein, Christian; Gimmon, Eli; Muñoz Schuffenegger, Pablo